• Thumbnail for Messenger RNA
    Messenger RNA (redirect from MRNA)
    In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is...
    49 KB (5,922 words) - 00:21, 9 May 2024
  • Thumbnail for MRNA vaccine
    An mRNA vaccine is a type of vaccine that uses a copy of a molecule called messenger RNA (mRNA) to produce an immune response. The vaccine delivers molecules...
    78 KB (7,926 words) - 15:19, 26 April 2024
  • Thumbnail for MRNA display
    mRNA display is a display technique used for in vitro protein, and/or peptide evolution to create molecules that can bind to a desired target. The process...
    16 KB (2,214 words) - 14:05, 2 September 2023
  • mRNA (or messenger RNA) is ribonucleic acid (RNA) that is read by the ribosome to produce a protein. mRNA may also refer to: Mitochondrial DNA (mDNA)...
    314 bytes (76 words) - 17:16, 10 October 2023
  • Thumbnail for Exon
    Exon (redirect from MRNA exon)
    excluded from mature mRNA transcripts by blocking the access of splice-directing small nuclear ribonucleoprotein particles (snRNPs) to pre-mRNA using Morpholino...
    13 KB (1,517 words) - 23:39, 2 April 2024
  • Thumbnail for Moderna COVID-19 vaccine
    those with high-risk medical conditions. It is an mRNA vaccine composed of nucleoside-modified mRNA (modRNA) encoding a spike protein of SARS-CoV-2, which...
    165 KB (13,017 words) - 17:59, 27 April 2024
  • mRNA-4157/V940 is an mRNA based cancer vaccine encapsulated in solid lipid nanoparticles. The 34 mRNA sequences in mRNA-4157/V940 vaccine were generated...
    9 KB (899 words) - 20:37, 28 April 2024
  • Thumbnail for Post-transcriptional modification
    correct translation of eukaryotic genomes because the initial precursor mRNA produced by transcription often contains both exons (coding sequences) and...
    11 KB (1,438 words) - 13:16, 13 April 2024
  • Thumbnail for Solid lipid nanoparticle
    some COVID-19 vaccines that use RNA vaccine technology coat the fragile mRNA strands with PEGylated lipid nanoparticles as their delivery vehicle (including...
    23 KB (2,629 words) - 15:37, 19 March 2024
  • more than a decade to develop. In contrast, mRNA is a molecule that can be made quickly, and research on mRNA to fight diseases was begun decades before...
    192 KB (22,024 words) - 10:32, 9 May 2024
  • Thumbnail for RNA-Seq
    RNA-Seq (redirect from MRNA-seq)
    differences in gene expression in different groups or treatments. In addition to mRNA transcripts, RNA-Seq can look at different populations of RNA to include...
    101 KB (11,031 words) - 07:40, 13 May 2024
  • Thumbnail for Translation (biology)
    anticodon sequences to mRNA codons. The tRNAs carry specific amino acids that are chained together into a polypeptide as the mRNA passes through and is...
    34 KB (3,974 words) - 16:41, 3 April 2024
  • which are: the two ribosomal subunits (50S and 30S subunits); the mature mRNA to be translated; the tRNA charged with N-formylmethionine (the first amino...
    23 KB (2,920 words) - 18:12, 24 April 2024
  • Thumbnail for MRNA-1283
    mRNA-1283 is a COVID-19 vaccine candidate developed by Moderna. An expectation, or hope seems to be that this "next generation" vaccine can be stored at...
    4 KB (275 words) - 09:58, 30 December 2023
  • Thumbnail for RNA splicing
    RNA splicing (redirect from MRNA splicing)
    a newly-made precursor messenger RNA (pre-mRNA) transcript is transformed into a mature messenger RNA (mRNA). It works by removing all the introns (non-coding...
    37 KB (4,480 words) - 08:47, 24 February 2024
  • Thumbnail for Protein biosynthesis
    produced in a premature form (pre-mRNA) which undergoes post-transcriptional modifications to produce mature mRNA. The mature mRNA is exported from the cell nucleus...
    40 KB (4,342 words) - 18:58, 2 April 2024
  • Thumbnail for Gene expression
    processing of pre-mRNA include 5′ capping, which is set of enzymatic reactions that add 7-methylguanosine (m7G) to the 5′ end of pre-mRNA and thus protect...
    81 KB (9,242 words) - 18:03, 29 April 2024
  • Antisense RNA is complementary to coding mRNA and is used to trigger mRNA inactivation to prevent the mRNA from being used in protein translation. RNAi-based...
    76 KB (8,848 words) - 17:12, 2 May 2024
  • mRNA surveillance mechanisms are pathways utilized by organisms to ensure fidelity and quality of messenger RNA (mRNA) molecules. There are a number of...
    29 KB (3,394 words) - 21:28, 16 March 2024
  • theory alleging that people vaccinated against COVID-19, especially with mRNA vaccines, are suffering from a high incidence of fast-developing cancers...
    7 KB (663 words) - 17:07, 27 April 2024
  • Thumbnail for Virus
    complementary to the viral messenger RNA (mRNA). Positive-sense viral RNA is in the same sense as viral mRNA and thus at least a part of it can be immediately...
    152 KB (18,121 words) - 16:36, 23 April 2024
  • Thumbnail for Transcription (biology)
    transcribed into RNA molecules that can encode proteins produce messenger RNA (mRNA). Other segments of DNA are transcribed into RNA molecules called non-coding...
    58 KB (6,780 words) - 13:42, 20 April 2024
  • Thumbnail for Alternative splicing
    messenger RNA (mRNA) produced from that gene. This means the exons are joined in different combinations, leading to different (alternative) mRNA strands. Consequently...
    64 KB (8,058 words) - 19:27, 11 May 2024
  • Thumbnail for Ribosome
    sequence of the amino acids in a protein is transcribed into a messenger RNA (mRNA) chain. Ribosomes bind to messenger RNAs and use their sequences[clarification...
    65 KB (7,265 words) - 21:10, 11 May 2024
  • Thumbnail for Untranslated region
    either of two sections, one on each side of a coding sequence on a strand of mRNA. If it is found on the 5' side, it is called the 5' UTR (or leader sequence)...
    12 KB (1,454 words) - 21:01, 18 January 2024
  • Thumbnail for Katalin Karikó
    vitro-transcribed messenger RNA (mRNA) for protein replacement therapy. Karikó laid the scientific groundwork for mRNA vaccines, overcoming major obstacles...
    39 KB (4,268 words) - 16:13, 10 May 2024
  • Thumbnail for RNA
    assembled as a chain of nucleotides. Cellular organisms use messenger RNA (mRNA) to convey genetic information (using the nitrogenous bases of guanine, uracil...
    64 KB (7,522 words) - 11:03, 8 May 2024
  • In enzymology, a mRNA guanylyltransferase (EC 2.7.7.50) is an enzyme that catalyzes the chemical reaction GTP + (5')ppPur-mRNA ⇌ {\displaystyle \rightleftharpoons...
    3 KB (319 words) - 15:00, 26 August 2023
  • Thumbnail for Gene
    corresponding RNA nucleotide sequence, which either encodes a protein (if it is an mRNA) or forms a 'structural' RNA, such as a transfer RNA (tRNA) or ribosomal...
    112 KB (12,720 words) - 01:27, 2 May 2024
  • Thumbnail for MicroRNA
    complementary sequences in mRNA molecules, then silence said mRNA molecules by one or more of the following processes: Cleavage of the mRNA strand into two pieces...
    146 KB (16,586 words) - 23:13, 26 April 2024