E-box (section MYOD1 (MyoD))
An E-box (enhancer box) is a DNA response element found in some eukaryotes that acts as a protein-binding site and has been found to regulate gene expression...
30 KB (3,663 words) - 06:09, 22 November 2023
When expressed, the myoD gene produces a protein referred to as MyoD (or MyoD1), which can bind certain DNA sequences, stop cell division, and elicit an...
19 KB (2,137 words) - 14:13, 14 July 2023
the sensitive detection of desmin, vimentin, muscle specific actin, and MyoD1. Similarly the rhabdomyoblast phenotype can be detected morphologically...
22 KB (2,414 words) - 18:11, 3 December 2023
ENSG00000085274 C2H2 ZF Known motif – High-throughput in vitro [562] AAAWTAARAGYC MYOD1 ENSG00000129152 bHLH Known motif – High-throughput in vitro [563] YGHCAGSTGKYV...
374 KB (81 words) - 02:10, 23 September 2023
context, PAX3-FOXO1 both (1) drives the expression of MYC, MYCN and even MYOD1 (a transcription factor highly expressed in all RMS subtypes) but also (2)...
50 KB (5,950 words) - 11:58, 30 January 2024
factor Mighty, which is negatively regulated by myostatin. We also found Myod1 and follistatin to be increased in response to decorin overexpression. Moreover...
36 KB (4,564 words) - 08:42, 19 February 2024
mutations that can cause ERMS include p53 loss, RAS pathway activation, MYOD1 mutations. Patients in the fusion-negative group had different genetic mutation...
34 KB (3,763 words) - 20:53, 6 January 2024
to interact with: AR, ELP2, EP300, EGFR, HIF1A, JAK1, JUN KHDRBS1, mTOR, MYOD1, NDUFA13, NFKB1, NR3C1, NCOA1, PML, RAC1, RELA, RET, RPA2, STAT1, Stathmin...
30 KB (3,569 words) - 19:52, 18 May 2024
10161 MYOCD HGNC:16067 Q8IZQ8 10162 MYOCOS HGNC:53429 A0A1B0GUC4 10163 MYOD1 HGNC:7611 P15172 10164 MYOF HGNC:3656 Q9NZM1 10165 MYOG HGNC:7612 P15173...
282 KB (17 words) - 23:17, 27 April 2024
MSC; MSGN1; MXD1; MXD3; MXD4; MXI1; MYC; MYCL1; MYCL2; MYCN; MYF5; MYF6; MYOD1; MYOG; NCOA1; NCOA3; NEUROD1; NEUROD2; NEUROD4; NEUROD6; NEUROG1; NEUROG2;...
14 KB (1,402 words) - 02:37, 3 December 2023
(March 1989). "A novel human muscle factor related to but distinct from MyoD1 induces myogenic conversion in 10T1/2 fibroblasts". The EMBO Journal. 8...
18 KB (2,355 words) - 11:57, 21 June 2022
Rinchik EM, Cavenee WK (March 1990). "Rhabdomyosarcoma-associated locus and MYOD1 are syntenic but separate loci on the short arm of human chromosome 11"...
11 KB (1,342 words) - 07:09, 18 December 2023
embryonic fibroblasts and that the activation of a single gene, later named MyoD1, is sufficient for such reprogramming. Compared with iPSCs whose reprogramming...
217 KB (25,002 words) - 18:56, 5 May 2024
from the dermomyotome and then Pax3 expression is turned off as Myf5 and MyoD1 expression is activated. To form other skeletal muscles, Pax3-expressing...
35 KB (4,371 words) - 10:33, 20 January 2024
Piette J., Bessereau J.-L., Huchet M., Changeux J.-P. (1990). Two adjacent MyoD1-binding sites regulate the expression of the acetylcholine receptor delta-subunit...
43 KB (5,468 words) - 06:00, 6 May 2024
suppressor genes p16, CDKN2B, and p14ARF for brain cancer; hypermethylation of MYOD1, CDH1, and CDH13 for cervical cancer; and hypermethylation of p16, p14,...
46 KB (4,969 words) - 10:48, 8 February 2024
with a variety of myoid markers, including desmin, myoglobin, myogenin, MYOD1 and muscle specific actin. They may also be positive with vimentin, smooth...
7 KB (1,049 words) - 22:41, 2 January 2024
PMC 5447133. PMID 28580170. Rekhi B, Upadhyay P, Ramteke MP, Dutt A (2016). "MYOD1 (L122R) mutations are associated with spindle cell and sclerosing rhabdomyosarcomas...
19 KB (2,006 words) - 18:25, 23 April 2024
BHLHE41 and BHLHE40 have been shown to repress myogenesis by blocking MYOD1 transcription. BHLHE40 and BHLHE41 are also known to alter the expression...
27 KB (3,150 words) - 12:41, 23 April 2024