• A metabotropic receptor, also referred to by the broader term G-protein-coupled receptor, is a type of membrane receptor that initiates a number of metabolic...
    6 KB (625 words) - 21:20, 9 July 2023
  • Thumbnail for Metabotropic glutamate receptor
    The metabotropic glutamate receptors, or mGluRs, are a type of glutamate receptor that are active through an indirect metabotropic process. They are members...
    34 KB (3,629 words) - 17:37, 18 March 2024
  • Thumbnail for Glutamic acid
    glutamate from the presynaptic cell. Glutamate acts on ionotropic and metabotropic (G-protein coupled) receptors. In the opposing postsynaptic cell, glutamate...
    35 KB (3,213 words) - 03:05, 31 March 2024
  • GABAergic signaling. Alcohol also modulates ionotropic GABA receptors. Metabotropic receptors are often G-protein-coupled receptors such as GABAB receptors...
    22 KB (2,705 words) - 08:12, 8 January 2024
  • Thumbnail for Metabotropic glutamate receptor 5
    Metabotropic glutamate receptor 5 is an excitatory Gq-coupled G protein-coupled receptor predominantly expressed on the postsynaptic sites of neurons....
    27 KB (3,218 words) - 03:13, 22 January 2024
  • Thumbnail for Glutamate receptor
    relaying information, but metabotropic ones are associated with a more prolonged stimulus. The signalling cascade induced by metabotropic receptor activation...
    63 KB (6,876 words) - 08:42, 14 April 2024
  • Thumbnail for Metabotropic glutamate receptor 1
    The glutamate receptor, metabotropic 1, also known as GRM1, is a human gene which encodes the metabotropic glutamate receptor 1 (mGluR1) protein. L-glutamate...
    22 KB (2,342 words) - 08:11, 10 March 2024
  • Thumbnail for Glutamate (neurotransmitter)
    into three major classes, known as AMPA receptors, NMDA receptors, and metabotropic glutamate receptors. A fourth class, known as kainate receptors, are...
    20 KB (2,177 words) - 10:32, 5 February 2024
  • Thumbnail for Metabotropic glutamate receptor 3
    Metabotropic glutamate receptor 3 (mGluR3) is an inhibitory Gi/G0-coupled G-protein coupled receptor (GPCR) generally localized to presynaptic sites of...
    28 KB (3,074 words) - 08:11, 10 March 2024
  • Thumbnail for Metabotropic glutamate receptor 8
    Metabotropic glutamate receptor 8 is a protein that in humans is encoded by the GRM8 gene. L-glutamate is the major excitatory neurotransmitter in the...
    6 KB (708 words) - 16:57, 28 November 2023
  • Thumbnail for Metabotropic glutamate receptor 4
    Metabotropic glutamate receptor 4 is a protein that in humans is encoded by the GRM4 gene. Together with GRM6, GRM7 and GRM8 it belongs to group III of...
    15 KB (1,839 words) - 07:49, 23 December 2023
  • Thumbnail for Metabotropic glutamate receptor 2
    Metabotropic glutamate receptor 2 (mGluR2) is a protein that, in humans, is encoded by the GRM2 gene. mGluR2 is a G protein-coupled receptor (GPCR) that...
    22 KB (2,647 words) - 08:11, 10 March 2024
  • Thumbnail for Metabotropic glutamate receptor 7
    Metabotropic glutamate receptor 7 is a protein that in humans is encoded by the GRM7 gene. L-glutamate is the major excitatory neurotransmitter in the...
    12 KB (1,359 words) - 23:10, 4 April 2024
  • Thumbnail for Metabotropic glutamate receptor 6
    Glutamate receptor, metabotropic 6, also known as GRM6 or mGluR6, is a protein which in humans is encoded by the GRM6 gene. L-glutamate is the major excitatory...
    7 KB (868 words) - 09:00, 18 August 2023
  • Thumbnail for Neurotransmitter receptor
    neurotransmitter receptors: ionotropic and metabotropic. Ionotropic means that ions can pass through the receptor, whereas metabotropic means that a second messenger...
    16 KB (1,590 words) - 01:49, 26 October 2023
  • Thumbnail for GABA receptor
    whereas GABAB receptors are G protein-coupled receptors, also called metabotropic receptors. It has long been recognized that, for neurons that are stimulated...
    35 KB (3,884 words) - 20:11, 11 February 2024
  • receptors for gamma-aminobutyric acid (GABA), therefore making them metabotropic receptors, that are linked via G-proteins to potassium channels. The...
    16 KB (1,564 words) - 20:19, 25 March 2024
  • Thumbnail for Methylene blue
    mGluR6Tooltip Metabotropic glutamate receptor 6 Agonists: Glutamate L-AP4 Antagonists: CPPG MAP4 MPPG MSOP MTPG UBP-1112 mGluR7Tooltip Metabotropic glutamate...
    53 KB (5,598 words) - 11:48, 16 January 2024
  • Thumbnail for Eglumetad
    mechanism. Eglumetad acts as a group-selective agonist for the group II metabotropic glutamate receptors (mGluR2/3). It is unclear whether eglumetad directly...
    17 KB (1,791 words) - 19:31, 20 December 2023
  • Thumbnail for 2F-NENDCK
    Allosteric modulators: AGN-241751 See also: Receptor/signaling modulators Metabotropic glutamate receptor modulators Glutamate metabolism/transport modulators...
    2 KB (167 words) - 00:08, 1 April 2024
  • (InterPro: IPR000337) are a class of G-protein coupled receptors that include the metabotropic glutamate receptors (InterPro: IPR000162) and several additional receptors...
    4 KB (251 words) - 19:09, 28 June 2022
  • Thumbnail for LY-341495
    acts as a potent and selective orthosteric antagonist for the group II metabotropic glutamate receptors (mGluR2/3). It is used in scientific research in...
    11 KB (1,011 words) - 19:32, 20 December 2023
  • Thumbnail for Nitrous oxide
    Allosteric modulators: AGN-241751 See also: Receptor/signaling modulators Metabotropic glutamate receptor modulators Glutamate metabolism/transport modulators...
    96 KB (10,073 words) - 04:52, 11 April 2024
  • Thumbnail for Ibotenic acid
    the NMDA and group I (mGluR1 and mGluR5) and II (mGluR2 and mGluR3) metabotropic glutamate receptors. It is inactive at group III mGluRs. Ibotenic acid...
    16 KB (1,473 words) - 07:42, 26 February 2024
  • Thumbnail for Xenon
    Allosteric modulators: AGN-241751 See also: Receptor/signaling modulators Metabotropic glutamate receptor modulators Glutamate metabolism/transport modulators...
    110 KB (11,984 words) - 06:03, 21 March 2024
  • Thumbnail for Ketamine
    Allosteric modulators: AGN-241751 See also: Receptor/signaling modulators Metabotropic glutamate receptor modulators Glutamate metabolism/transport modulators...
    117 KB (11,325 words) - 19:12, 18 April 2024
  • Thumbnail for Neuron
    that are excitatory at ionotropic receptors and a modulatory effect at metabotropic receptors. Similarly, GABA acts on several types of receptors, but all...
    77 KB (8,964 words) - 12:43, 25 March 2024
  • Thumbnail for Dextromethorphan
    Allosteric modulators: AGN-241751 See also: Receptor/signaling modulators Metabotropic glutamate receptor modulators Glutamate metabolism/transport modulators...
    50 KB (4,560 words) - 21:22, 9 April 2024
  • Thumbnail for G protein-coupled receptor
    (Rhodopsin-like) Class B (or 2) (Secretin receptor family) Class C (or 3) (Metabotropic glutamate/pheromone) Class D (or 4) (Fungal mating pheromone receptors)...
    82 KB (9,376 words) - 08:31, 7 March 2024
  • Thumbnail for Magnesium
    Allosteric modulators: AGN-241751 See also: Receptor/signaling modulators Metabotropic glutamate receptor modulators Glutamate metabolism/transport modulators...
    69 KB (7,703 words) - 09:02, 10 April 2024