many methods to investigate protein–protein interactions which are the physical contacts of high specificity established between two or more protein molecules...

direct physical interactions between protein pairs, named “binary” methods, while there are other techniques that measure physical interactions among groups...

non-covalent interactions, such as hydrogen bonding, ionic interactions, Van der Waals forces, and hydrophobic packing. To understand the functions of proteins at...

catalog physical interactions between pairs or groups of proteins. Understanding protein–protein interactions is important for the investigation of intracellular...

Protein–protein interaction screening refers to the identification of Protein–protein interaction with high-throughput screening methods such as computer-...

protein crystallization is to optimize the number of bonds one can form with another protein through intermolecular interactions. These interactions depend...

DAP-seq are used in the laboratory to investigate DNA-protein interaction in vivo and in vitro. The protein–DNA interactions can be modulated using stimuli...

interact to form a fully functional quaternary protein. Folding is a spontaneous process that is mainly guided by hydrophobic interactions, formation...

and protein threading.[page needed] These methods involve free modeling without using any structural information about the template. Ab initio methods are...

local compactness in proteins have been used in many of the early methods of domain assignment and in several of the more recent methods. One of the first...

The green fluorescent protein (GFP) is a protein that exhibits green fluorescence when exposed to light in the blue to ultraviolet range. The label GFP...

proteins in proteomics. It can also be used to localize proteins to the various organelles, and determine the interactions between different proteins...

experimental methods such as phage display and in silico computational methods. Knowledge of protein-protein interactions is especially useful in regard to biological...

molecular interactions in a particular cell. The term specifically refers to physical interactions among molecules (such as those among proteins, also known...

biology technique used to discover protein–protein interactions (PPIs) and protein–DNA interactions by testing for physical interactions (such as binding)...

biomolecular interactions, including protein-protein interactions, small molecule/fragment-protein interactions, etc. Its technology is often used to measure...

Antifreeze proteins (AFPs) or ice structuring proteins refer to a class of polypeptides produced by certain animals, plants, fungi and bacteria that permit...

Lattanzi G, Carloni P (June 2009). "G protein inactive and active forms investigated by simulation methods". Proteins. 75 (4): 919–30. doi:10.1002/prot.22303...

The tau proteins (abbreviated from tubulin associated unit) form a group of six highly soluble protein isoforms produced by alternative splicing from the...

fluorescent labeling methods. The method with the highest adoption rate for determining DNA-binding proteins and protein-DNA interactions is the electrophoretic...

electrostatic and hydrogen bonding interactions. Theoretical investigations pointed to correlated effects of protein-binding onto binding affinities during...

typically used to validate protein interactions. It is based on the association of fluorescent protein fragments that are attached to components of the...

genetic interactions between multiple phosphorylating proteins and their targets. This reveals interesting recurring patterns of interactions – network...

experimenter to investigate and select specific types of connections between nuclei. The array of nuclear magnetic resonance experiments used on proteins fall...

"Illuminating insights into protein-protein interactions using bioluminescence resonance energy transfer (BRET)". Nature Methods. 3 (3): 165–74. doi:10.1038/nmeth841...

being adjacent in a folded protein, or even by being adjacent in an oligomer of that protein). Several statistical methods exist to extract from a multiple...

cycle regulator developed through research investigating mechanisms of interactions with E2F family member proteins. Yet, more data generated from biochemical...

express diverse RBPs with unique RNA-binding activity and protein–protein interaction. According to the Eukaryotic RBP Database (EuRBPDB), there are 2961...

known to be relatively weak interactions, small stabilizing interactions can add up to make an important contribution to the overall stability of a conformer...

termed activators of G-protein signalling (AGS). Both the ubiquity of these interactions and the importance of Gα vs. Gβγ subunits to these processes are...