3-Methylglutaconyl-CoA hydratase, also known as MG-CoA hydratase and AUH, is an enzyme (EC 4.2.1.18) encoded by the AUH gene on chromosome 19. It is a...

Enoyl-CoA hydratase (ECH) or crotonase is an enzyme EC 4.2.1.17 that hydrates the double bond between the second and third carbons on 2-trans/cis-enoyl-CoA:...

leucine. It is metabolized into HMG-CoA. Methylcrotonyl-CoA carboxylase Methylglutaconyl-CoA hydratase Wilson JM, Fitschen PJ, Campbell B, Wilson GJ, Zanchi...

catalyzed by four respective enzymes, namely acyl-CoA dehydrogenase, enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, and thiolase. The cycle produces...

precursors are β-methylglutaconyl-CoA (MG-CoA) and β-hydroxy β-methylbutyryl-CoA (HMB-CoA). HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic...

subsequently converted to HMG-CoA by methylglutaconyl-CoA hydratase. HMG-CoA is then cleaved into acetyl-CoA and acetoacetate by HMG-CoA lyase or used in the production...

subsequently converted to HMG-CoA by methylglutaconyl-CoA hydratase. HMG-CoA is then cleaved into acetyl-CoA and acetoacetate by HMG-CoA lyase or used in the production...

3-Methylglutaconic aciduria type I, 3-Methylglutaconic acidemia or 3-Methylglutaconyl-CoA Hydratase Deficiency Mutations in the AUH gene cause 3-methylglutaconic...

CoA, to form 3-methylglutaconyl CoA. MCC is covalently modified and inhibited by intermediates of leucine catabolism including 3-methylglutaconyl-CoA...

diverts methylcrotonyl CoA to 3-hydroxyisovaleryl CoA in a reaction catalyzed by enoyl-CoA hydratase (22, 23). 3-Hydroxyisovaleryl CoA accumulation can inhibit...

Yundong (2017-09-07). "Chromodomain Protein CDYL Acts as a Crotonyl-CoA Hydratase to Regulate Histone Crotonylation and Spermatogenesis". Molecular Cell...

metabolism disorders, among them 4-hydroxybutyric aciduria, 3-methylglutaconyl-Co A hydratase deficiency, multiple carboxylase deficiency, methylmalonic...

diverts methylcrotonyl CoA to 3-hydroxyisovaleryl CoA in a reaction catalyzed by enoyl-CoA hydratase (22, 23). 3-Hydroxyisovaleryl CoA accumulation can inhibit...

butyric aciduria Isobutyryl-CoA dehydrogenase deficiency 2-Methylbutyryl-CoA dehydrogenase deficiency 3-Methylglutaconyl-CoA hydratase deficiency Glutaric acidemia...

methylcrotonic aciduria 3 methylglutaconyl coa hydratase deficiency 3-hydroxy 3-methyl glutaryl-coa lyase deficiency 3-hydroxyacyl-coa dehydrogenase deficiency...

19, threonine ammonia-lyase EC 4.2.1.17: enoyl-CoA hydratase EC 4.2.1.18: methylglutaconyl-CoA hydratase EC 4.2.1.19: imidazoleglycerol-phosphate dehydratase...

enzymology, an isovaleryl-CoA dehydrogenase (EC 1.3.8.4) is an enzyme that catalyzes the chemical reaction 3-methylbutanoyl-CoA + acceptor ⇌ {\displaystyle...

step involves the conversion of HMG-CoA to methyl glutaconyl-CoA via enoyl-CoA hydratase (Fer4). Methyl glutaconyl-CoA is then coupled with hydroxy ornithine...

3-Methylcrotonyl-CoA (β-Methylcrotonyl-CoA or MC-CoA) is an intermediate in the metabolism of leucine. It is found in mitochondria, where it is formed...

Isovaleryl-coenzyme A, also known as isovaleryl-CoA, is an intermediate in the metabolism of branched-chain amino acids. Isovaleryl coenzyme A dehydrogenase...

cofactors present, including cholesterol, acetyl-CoA, isovaleryl-CoA, and other biological molecules. Isovaleryl-CoA is the main compound synthesized from ɑ-KIC...

containing this residue are found at the active site of some nitrile hydratases. Akter, Salma; Fu, Ling; Jung, Youngeun; Conte, Mauro Lo; Lawson, J. Reed;...

of ammonium. In the liver, urocanic acid is transformed by urocanate hydratase (or urocanase) to 4-imidazolone-5-propionic acid and subsequently to glutamic...

relevant to type II diabetes. Formiminoglutamic acid Urocanate Urocanate hydratase Hassall, H.; Greenberg, D. M. (1971). "Preparation and properties of...