• A molecular clamp is a polypeptide used to maintain the shape of proteins in some experimental vaccines. On a virus, pre-fusion proteins on their surface...
    6 KB (634 words) - 00:04, 10 November 2023
  • Thumbnail for DNA clamp
    A DNA clamp, also known as a sliding clamp, is a protein complex that serves as a processivity-promoting factor in DNA replication. As a critical component...
    23 KB (2,044 words) - 07:04, 10 March 2024
  • association of alpha and beta tubulin monomers, functioning as a "molecular clamp" rather than inducing neo-associations. In 2000, the revelation that...
    19 KB (2,100 words) - 04:11, 15 April 2024
  • Thumbnail for V451 vaccine
    Limited. The vaccine candidate used the University of Queensland's molecular clamp technology and the MF59 adjuvant. V451 is a protein subunit vaccine...
    6 KB (421 words) - 03:40, 24 November 2023
  • Thumbnail for Hsp90
    Hsp90 (category Molecular chaperones)
    conformational changes that clamp the Hsp90 down onto the substrate. In a reaction similar to that of other molecular clamp proteins like GyrB and MutL...
    51 KB (5,537 words) - 19:57, 8 February 2024
  • Thumbnail for Patch clamp
    The patch clamp technique is a laboratory technique in electrophysiology used to study ionic currents in individual isolated living cells, tissue sections...
    30 KB (3,855 words) - 08:33, 29 February 2024
  • Thumbnail for Electrophysiology
    (Loligo pealei), and were among the first applications of the "voltage clamp" technique. Today, most microelectrodes used for intracellular recording...
    38 KB (4,430 words) - 00:47, 3 April 2024
  • Thumbnail for Voltage clamp
    The voltage clamp is an experimental method used by electrophysiologists to measure the ion currents through the membranes of excitable cells, such as...
    26 KB (3,681 words) - 06:30, 11 January 2024
  • Thumbnail for Xeno nucleic acid
    if it was simply a coincidental occurrence. XNA may be employed as molecular clamps in quantitative real-time polymerase chain reactions (qPCR) by hybridizing...
    14 KB (1,677 words) - 10:31, 24 April 2024
  • and quantifying insulin resistance is the "hyperinsulinemic euglycemic clamp," so-called because it measures the amount of glucose necessary to compensate...
    53 KB (6,297 words) - 13:30, 7 April 2024
  • Thumbnail for Dihydrogen cation
    ten discrete states of the hydrogen molecular ion (clamped nuclei case). For general diatomic and polyatomic molecular systems, the exchange energy is thus...
    29 KB (3,518 words) - 19:59, 19 April 2024
  • Thumbnail for Coalition for Epidemic Preparedness Innovations
    given to the University of Queensland to fund the development of a "molecular clamp" vaccine platform, that CEPI described as a "transformative technology...
    56 KB (5,131 words) - 09:16, 18 April 2024
  • (intracellular recording of the properties of single neurons), such as patch clamp, voltage clamp, extracellular single-unit recording and recording of local field...
    16 KB (1,838 words) - 07:36, 14 April 2024
  • Thumbnail for Chaperone (protein)
    In molecular biology, molecular chaperones are proteins that assist the conformational folding or unfolding of large proteins or macromolecular protein...
    29 KB (3,499 words) - 07:16, 20 February 2024
  • mechanical way. Within this framework the molecular Hamiltonian has been simplified to the so-called clamped nucleus Hamiltonian, also called electronic...
    38 KB (4,808 words) - 23:48, 14 June 2023
  • Thumbnail for GHKL domain
    TRAP1, TRRAP Prodromou C, Roe SM, Piper PW, Pearl LH (June 1997). "A molecular clamp in the crystal structure of the N-terminal domain of the yeast Hsp90...
    7 KB (437 words) - 02:06, 31 July 2023
  • Thumbnail for POU2AF1
    Both the POU-Specific Domain and the POU Homeodomain and Acts as a Molecular Clamp on DNA". Mol. Cell. Biol. 18 (12): 7397–409. doi:10.1128/MCB.18.12...
    12 KB (1,482 words) - 17:44, 2 January 2024
  • such as intracellular recording, patch-clamp, and voltage-clamp technique, pharmacology, confocal imaging, molecular biology, two photon laser scanning microscopy...
    12 KB (1,396 words) - 00:49, 27 February 2024
  • the processivity of the DNA polymerases performing the replication. DNA clamp proteins are integral components of the DNA replication machinery and serve...
    6 KB (826 words) - 20:25, 10 September 2023
  • Thumbnail for DNA replication
    DNA replication (category Molecular biology)
    In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule. DNA replication...
    60 KB (7,306 words) - 20:48, 25 March 2024
  • Thumbnail for DNA polymerase
    catalyze the synthesis of DNA molecules from nucleoside triphosphates, the molecular precursors of DNA. These enzymes are essential for DNA replication and...
    59 KB (7,054 words) - 22:05, 29 March 2024
  • Thumbnail for CBFB
    leukemia-associated AML1 (Runx1)--CBF beta complex functions as a DNA-induced molecular clamp". Nat. Struct. Biol. 8 (4): 371–8. doi:10.1038/86264. PMID 11276260...
    9 KB (1,195 words) - 02:01, 23 December 2023
  • Thumbnail for Soluble NSF attachment protein
    dependent ion channels permits the influx of Ca2+ into the cell where the molecular clamp protein (a SNARE) called synaptotagmin acts in a Ca2+ sensitive manner...
    27 KB (3,344 words) - 10:15, 3 December 2023
  • Thumbnail for Okazaki fragments
    Okazaki fragments (category Molecular biology)
    during DNA replication. They were discovered in the 1960s by the Japanese molecular biologists Reiji and Tsuneko Okazaki, along with the help of some of their...
    33 KB (4,435 words) - 04:51, 11 April 2024
  • quantum chemistry and molecular physics, the Born–Oppenheimer (BO) approximation is the best-known mathematical approximation in molecular dynamics. Specifically...
    30 KB (5,075 words) - 06:31, 15 February 2024
  • Thumbnail for Jackal
    M.; Mikkelsen, T. S.; Karlsson, E. K.; Jaffe, D. B.; Kamal, M. Jdjndnd; Clamp, M.; Chang, J. L.; Kulbokas, E. J.; Zody, M. C.; Mauceli, E.; Xie, X.; Breen...
    17 KB (1,481 words) - 21:25, 16 April 2024
  • voltage clamp, which is an electronic feedback circuit, allows the experimenter to maintain the membrane potential at a fixed point and the voltage clamp then...
    9 KB (1,079 words) - 05:36, 13 October 2022
  • Thumbnail for Endoglin
    intermolecular disulfide, involving cysteine 582, this generates a molecular clamp that secures the ligand via interaction of two copies of OR1 with the...
    25 KB (2,839 words) - 04:28, 11 April 2024
  • Thumbnail for HSP90AB1
    PMID 2925609. Prodromou C, Roe SM, Piper PW, Pearl LH (Jun 1997). "A molecular clamp in the crystal structure of the N-terminal domain of the yeast Hsp90...
    25 KB (3,113 words) - 21:55, 11 April 2024
  • Automated patch clamping is beginning to replace manual patch clamping as a method to measure the electrical activity of individual cells. Different techniques...
    19 KB (2,412 words) - 03:08, 13 April 2024