 | Nephrin is a protein necessary for the proper functioning of the renal filtration barrier. The renal filtration barrier consists of fenestrated endothelial... 11 KB (1,352 words) - 07:01, 2 May 2023 |
 | When infants are born with certain defects in these proteins, such as nephrin and CD2AP, their kidneys cannot function. People have variations in these... 17 KB (1,781 words) - 08:50, 19 March 2024 |
 | slits are covered by a diaphragm that includes the transmembrane protein nephrin. Goodpasture's syndrome is also known as anti-glomerular basement membrane... 5 KB (382 words) - 17:45, 21 June 2023 |
 | been implicated in FSGS. These include: NPHS1, which encodes the protein nephrin that contributes to the filtration barrier; NPHS2, which encodes the protein... 20 KB (2,265 words) - 08:29, 26 April 2024 |
 | adult minimal change disease cases exhibited serum autoantibodies against nephrin, a structural protein located in the podocyte slit diaphragm. There has... 16 KB (1,821 words) - 06:51, 26 April 2024 |
 | expressed in the different compartments of the kidney with podocin and nephrin expressed in glomeruli, Solute carrier family protein SLC22A8 expressed... 61 KB (6,896 words) - 17:09, 20 April 2024 |
 | slit diaphragms consisting of a mat of proteins, including podocin and nephrin. In addition, foot processes have a negatively charged coat (glycocalyx)... 17 KB (1,802 words) - 18:09, 14 November 2023 |
 | glomerular disease. CD2AP has been shown to interact with: Cbl gene, NPHS2, Nephrin, and RAB4A. Focal segmental glomerulosclerosis GRCh38: Ensembl release... 11 KB (1,288 words) - 02:16, 24 December 2023 |
and C-terminus, the latter of which interacts with the cytosolic tail of nephrin, with CD2AP serving as an adaptor. Podocin is localized on the membranes... 3 KB (317 words) - 18:57, 31 December 2023 |
 | yet to be discovered. However, mutations in podocyte proteins, such as nephrin, alpha-actinin 4, and podocin, are associated with proteinuria and nephrotic... 7 KB (768 words) - 18:15, 25 March 2024 |
 | humans is encoded by the NPHS2 gene. NPHS2 has been shown to interact with Nephrin and CD2AP. Focal segmental glomerulosclerosis GRCh38: Ensembl release 89:... 8 KB (1,036 words) - 21:47, 27 March 2024 |
 | epithelial cells also seem to secrete an unknown mediator that reduces nephrin synthesis and distribution.[citation needed] Within membranous glomerulonephritis... 22 KB (2,291 words) - 16:52, 1 November 2023 |
syndrome: NPHS1 (Finnish Type): The gene NPHS1 encodes for the protein nephrin. This genetic variant is characterized by severe protein loss in the first... 13 KB (1,401 words) - 17:52, 2 September 2023 |
 | ciliopathies. Another report utilising an isogenic control demonstrated abnormal nephrin localisation in the glomeruli of kidney organoids generated from a patient... 82 KB (9,321 words) - 02:46, 1 May 2024 |
| al., 2003). [supplied by OMIM] KIRREL has been shown to interact with Nephrin and Tight junction protein 1. GRCh38: Ensembl release 89: ENSG00000183853... 6 KB (674 words) - 21:09, 27 March 2024 |
 | β-Catenin, CDH1, CDH2, Collagen, type XVII, alpha 1, Cortactin, FYN, MUC1, Nephrin, PSEN1, PTPN6, PTPRJ, PTPRM, VE-cadherin, YES1, and ZBTB33 δ-Catenin Catenin... 18 KB (2,053 words) - 02:39, 16 April 2024 |
 | congenital nephrotic syndrome is a rare genetic disorder in which the protein nephrin, a component of the glomerular filtration barrier, is altered. Drugs (... 59 KB (6,567 words) - 07:17, 26 April 2024 |
 | B, Kurfis J, Rahmanuddin S, Kanwar YS, Chugh SS (Jul 2003). "Neph1 and nephrin interaction in the slit diaphragm is an important determinant of glomerular... 16 KB (2,033 words) - 19:34, 28 January 2023 |
 | NEPH1 (KIRREL) and NEPH3 (KIRREL2). The NEPH proteins can interact with nephrin and CASK. NEPH2 has been implicated in synapse formation. Disruption of... 6 KB (827 words) - 09:13, 29 March 2024 |
 | with: Beta-catenin, CDH1, Catenin (cadherin-associated protein), alpha 1, Nephrin and Plakoglobin. Cadherin-3 was first described in 1986 by Masatoshi Takeichi's... 11 KB (1,422 words) - 01:43, 3 December 2023 |
 | KCNJ4 APBA1 ATP2B4 CINAP and TBR1 DLG1 DLG4 F11 receptor ID1 KCNJ12 LIN7A Nephrin Parkin (ligase) RPH3A SDC2 CASK Research Foundation - A non-profit based... 26 KB (2,890 words) - 00:48, 3 December 2023 |
 | FYB, FASLG, GNB2L1, GRIN2A, ITK, Janus kinase 2, KHDRBS1, Lck, LKB1, Nephrin, PAG1, PIK3R2, PRKCQ, PTK2B, PTK2, PTPRT UNC119, RICS, SH2D1A, SKAP1, Syk... 40 KB (4,778 words) - 18:07, 30 March 2024 |
| Ahola H, Valtonen E, Holthofer H (Dec 2002). "Filtrin is a novel member of nephrin-like proteins". Biochem Biophys Res Commun. 300 (2): 364–70. doi:10... 4 KB (477 words) - 07:13, 30 November 2023 |
 | Zhang Y, Liang YZ (April 2009). "[Effect of bone morphogenic protein 7 on nephrin expression and distribution in diabetic rat kidneys]". Nan Fang Yi Ke da... 21 KB (2,565 words) - 05:39, 19 March 2024 |
et al. (2005). "Evidence linking glycated albumin to altered glomerular nephrin and VEGF expression, proteinuria, and diabetic nephropathy". Kidney Int... 14 KB (1,404 words) - 11:57, 8 April 2024 |
Karl (1998). "Positionally Cloned Gene for a Novel Glomerular Protein—Nephrin—Is Mutated in Congenital Nephrotic Syndrome". Molecular Cell. 1 (4): 575–582... 16 KB (1,576 words) - 12:57, 16 January 2024 |
 | Sugimoto H, Kalluri R, Grande JP (Apr 2007). "Glomerular expression of nephrin and synaptopodin, but not podocin, is decreased in kidney sections from... 8 KB (1,051 words) - 09:14, 17 November 2023 |
synaptic plasticity and memory formation. Additionally, the protein binds to nephrin and CD2AP within the kidneys, where can help with intracellular signaling... 15 KB (2,092 words) - 08:25, 27 January 2023 |
syndrome). The last project is examining the interactions and pathology of nephrin, a protein found in podocytes. The long-term goal for these three projects... 16 KB (1,797 words) - 09:34, 7 April 2024 |