• Neurotrophic factors (NTFs) are a family of biomolecules – nearly all of which are peptides or small proteins – that support the growth, survival, and...
    16 KB (1,784 words) - 04:08, 6 January 2024
  • Thumbnail for Brain-derived neurotrophic factor
    growth factors, which are related to the canonical nerve growth factor (NGF), a family which also includes NT-3 and NT-4/NT-5. Neurotrophic factors are found...
    45 KB (5,339 words) - 00:15, 22 March 2024
  • Thumbnail for Ciliary neurotrophic factor
    Ciliary neurotrophic factor is a protein that in humans is encoded by the CNTF gene. The protein encoded by this gene is a polypeptide hormone and neurotrophic...
    15 KB (1,740 words) - 14:38, 3 December 2023
  • Thumbnail for Glial cell line-derived neurotrophic factor
    Glial cell line-derived neurotrophic factor (GDNF) is a protein that, in humans, is encoded by the GDNF gene. GDNF is a small protein that potently promotes...
    23 KB (2,730 words) - 03:52, 9 July 2023
  • Thumbnail for Lithium (medication)
    phosphoinositide cycle. Various neurotrophic factors such as BDNF and mesencephalic astrocyte-derived neurotrophic factor have been shown to be modulated...
    90 KB (9,543 words) - 09:52, 10 May 2024
  • Thumbnail for Neurotrophin
    synonym for neurotrophic factor, but the term neurotrophin is more generally reserved for four structurally related factors: nerve growth factor (NGF), brain-derived...
    27 KB (3,069 words) - 05:55, 26 February 2024
  • The survival of neurons is regulated by survival factors, called trophic factors. The neurotrophic hypothesis was formulated by Victor Hamburger and...
    57 KB (6,872 words) - 14:44, 26 April 2024
  • Thumbnail for Nerve injury
    important role in not only producing neurotrophic factors such as nerve growth factor (NGF) and ciliary neurotrophic factor (CNTF), which promote growth, of...
    34 KB (4,113 words) - 20:59, 13 February 2024
  • fibroblast growth factors and vascular endothelial growth factors stimulate blood vessel differentiation (angiogenesis). Growth factor is sometimes used...
    10 KB (1,131 words) - 19:14, 31 March 2024
  • Examples of notable neurotrophic factors include: Insulin-like growth factor-1 (IGF-1) Glial cell line-derived neurotrophic factor (GDNF) Vascular endothelial...
    6 KB (596 words) - 17:05, 17 June 2022
  • Thumbnail for Biology of bipolar disorder
    generally more consistent, and observe HPA hyperactivity. Brain derived neurotrophic factor levels are peripherally reduced in both manic and depressive phases...
    97 KB (11,128 words) - 13:42, 1 May 2024
  • in various directions independently of the radial glial fibers. Neurotrophic factors are molecules which promote and regulate neuronal survival in the...
    52 KB (6,411 words) - 14:43, 26 April 2024
  • Thumbnail for Tropomyosin receptor kinase B
    also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type 2 is a protein that in humans...
    40 KB (4,321 words) - 10:20, 23 March 2024
  • neurotrophic factors and only a fraction survive while others die by programmed cell death. Furthermore, the theory states that predetermined factors...
    55 KB (6,757 words) - 08:43, 9 May 2024
  • Thumbnail for Nerve growth factor
    Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival...
    23 KB (2,786 words) - 23:53, 26 April 2024
  • brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), nerve growth factor (NGF), and ciliary neurotrophic factor (CNTF)...
    12 KB (1,049 words) - 10:54, 12 January 2024
  • Thumbnail for Glial scar
    several cytokines, bioactive lipids, coagulation factors, reactive oxygen intermediates, and neurotrophic factors. The expression of these molecules depends...
    23 KB (2,950 words) - 22:34, 18 January 2023
  • Thumbnail for Alpha motor neuron
    spinal cord. In addition to receiving neurotrophic factors from muscles, α-MNs also secrete a number of trophic factors to support the muscle fibers they...
    16 KB (1,982 words) - 06:24, 16 November 2023
  • (MDD) is caused, at least partly, by impaired neurotrophic support. Neurotrophic factors (also known as neurotrophins) are a family of closely related proteins...
    6 KB (635 words) - 22:28, 8 October 2023
  • number of factors in the PNS system. Some factors include Schwann cell characteristics, neurotrophic factors, and nerve branch size. These factors influence...
    19 KB (2,307 words) - 20:04, 26 July 2022
  • which specifically bind to neurotrophins (neurotrophic factors). Two classes of neurotrophic factor receptors are the p75 and the "Trk" families of Tyrosine...
    5 KB (670 words) - 17:28, 23 January 2021
  • depressive disorder is heavily influenced by environmental and genetic factors. These factors include epigenetic modification of the genome which may result in...
    35 KB (4,421 words) - 00:27, 27 January 2024
  • Thumbnail for Insulin-like growth factor 1
    S2CID 24843614. Winston BW, Ni A, Aurora RC (2006). "Insulin-like Growth Factors". In Laurent GJ, Shapiro SD (eds.). Encyclopedia of Respiratory Medicine...
    37 KB (4,461 words) - 19:39, 12 May 2024
  • Thumbnail for Neurotrophin-3
    this gene, NT-3, is a neurotrophic factor in the NGF (Nerve Growth Factor) family of neurotrophins. It is a protein growth factor which has activity on...
    14 KB (1,816 words) - 04:39, 31 October 2023
  • Neuroprotective effects – Reactive astrocytes release neurotrophic factors, such as glial cell-derived neurotrophic factor (GDNF), which protects against programmed...
    30 KB (3,573 words) - 15:14, 3 December 2023
  • specific, VEGF is a sub-family of growth factors, the platelet-derived growth factor family of cystine-knot growth factors. They are important signaling proteins...
    40 KB (4,578 words) - 20:20, 10 March 2024
  • The ciliary neurotrophic factor receptor, also known as CNTFR, binds the ciliary neurotrophic factor. This receptor and its cognate ligand support the...
    2 KB (146 words) - 00:52, 1 December 2023
  • the production of neurotrophic factors (compounds that promote growth or survival of neurons), such as brain-derived neurotrophic factor (BDNF), insulin-like...
    112 KB (12,449 words) - 23:10, 28 April 2024
  • neurotropic and neurotrophic communication between the proximal and distal ends of the nerve gap, block external inhibitory factors, and provide a physical...
    106 KB (14,559 words) - 06:09, 22 January 2024
  • Thumbnail for Regeneron Pharmaceuticals
    New York. The company was founded in 1988. Originally focused on neurotrophic factors and their regenerative capabilities, giving rise to its name, the...
    26 KB (2,237 words) - 08:36, 9 May 2024