• Thumbnail for Nucleosome
    A nucleosome is the basic structural unit of DNA packaging in eukaryotes. The structure of a nucleosome consists of a segment of DNA wound around eight...
    56 KB (6,714 words) - 16:27, 7 May 2024
  • The nucleosome repeat length, (NRL) is the average distance between the centers of neighboring nucleosomes. NRL is an important physical chromatin property...
    5 KB (590 words) - 07:06, 3 December 2023
  • forming nucleosomes and the so-called beads on a string structure (euchromatin). Multiple histones wrap into a 30-nanometer fiber consisting of nucleosome arrays...
    55 KB (5,949 words) - 18:00, 24 March 2024
  • Thumbnail for Histone octamer
    histone octamer is the eight-protein complex found at the center of a nucleosome core particle. It consists of two copies of each of the four core histone...
    19 KB (2,478 words) - 00:36, 26 January 2024
  • Nucleosome Remodeling Factor (NURF) is an ATP-dependent chromatin remodeling complex first discovered in Drosophila melanogaster (fruit fly) that catalyzes...
    5 KB (569 words) - 16:35, 7 May 2024
  • wrapping of DNA around proteins called histones in order to form condensed nucleosomes. The double helix was discovered in 1953 by James Watson and Francis...
    7 KB (857 words) - 10:18, 3 January 2023
  • Thumbnail for Epigenetics
    of the chromatin remodeling protein, ALC1, that can cause nucleosome remodeling. Nucleosome remodeling has been found to cause, for instance, epigenetic...
    161 KB (18,430 words) - 14:53, 15 May 2024
  • Thumbnail for Endurance
    acetylations removed from H3K27 in nucleosomes located at the enhancers that control those genes (see Figure "A nucleosome with histone tails set for transcriptional...
    16 KB (1,520 words) - 15:16, 11 March 2024
  • Thumbnail for S phase
    Labeling experiments indicate that nucleosome duplication is predominantly conservative. The paternal H3-H4 core nucleosome remains completely segregated from...
    15 KB (1,681 words) - 15:45, 29 October 2023
  • Thumbnail for Chromosome
    organism. In most chromosomes, the very long thin DNA fibers are coated with nucleosome-forming packaging proteins; in eukaryotic cells the most important of...
    65 KB (6,604 words) - 13:32, 12 May 2024
  • Thumbnail for NAP1L3
    Nucleosome assembly protein 1 like 3 is a protein that in humans is encoded by the NAP1L3 gene. This gene is intronless and encodes a member of the nucleosome...
    744 bytes (133 words) - 09:05, 27 March 2022
  • Thumbnail for Histone
    spools around which DNA winds to create structural units called nucleosomes. Nucleosomes in turn are wrapped into 30-nanometer fibers that form tightly...
    86 KB (9,575 words) - 18:04, 19 April 2024
  • Thumbnail for Chromatosome
    molecular biology, a chromatosome is a result of histone H1 binding to a nucleosome, which contains a histone octamer and DNA. The chromatosome contains 166...
    2 KB (223 words) - 19:05, 2 December 2023
  • linker DNA is double-stranded DNA (38-53 base pairs long) in between two nucleosome cores that, in association with histone H1, holds the cores together....
    1 KB (191 words) - 10:43, 30 December 2022
  • Thumbnail for Cellular differentiation
    nucleosome is covering a given genomic binding site or not. This can be determined using a chromatin immunoprecipitation (ChIP) assay. DNA-nucleosome...
    50 KB (6,014 words) - 16:51, 15 May 2024
  • fragmentation entropy (PFE), an adjusted Shannon Index for entropy, and nucleosome-depleted region (NDR) score, the depth of sequencing in NDR regions. PFE...
    58 KB (6,303 words) - 04:19, 15 May 2024
  • chromatin remodeling complexes which either move, eject or restructure nucleosomes. Besides actively regulating gene expression, dynamic remodeling of chromatin...
    50 KB (5,523 words) - 09:43, 3 December 2023
  • Thumbnail for Histone acetylation and deacetylation
    residues within the N-terminal tail protruding from the histone core of the nucleosome are acetylated and deacetylated as part of gene regulation. Histone acetylation...
    58 KB (7,036 words) - 21:48, 28 February 2024
  • Thumbnail for Nucleoprotein
    acids (either DNA or RNA). Typical nucleoproteins include ribosomes, nucleosomes and viral nucleocapsid proteins. Nucleoproteins tend to be positively...
    18 KB (1,964 words) - 23:55, 6 March 2024
  • Thumbnail for Euchromatin
    known as nucleosomes, reminiscent of an unfolded set of beads on a string, that are approximately 11 nm in diameter. At the core of these nucleosomes are a...
    17 KB (1,764 words) - 08:04, 26 November 2023
  • Thumbnail for DNA
    proteins are involved. The histones form a disk-shaped complex called a nucleosome, which contains two complete turns of double-stranded DNA wrapped around...
    166 KB (17,845 words) - 19:31, 23 March 2024
  • Thumbnail for Nucleic acid double helix
    advances such as X-ray crystallography of DNA duplexes and later the nucleosome core particle, and the discovery of topoisomerases. Also, the non-double-helical...
    42 KB (5,016 words) - 22:06, 7 April 2024
  • In the field of molecular biology, the Mi-2/NuRD (Nucleosome Remodeling Deacetylase) complex, is a group of associated proteins with both ATP-dependent...
    11 KB (1,242 words) - 15:04, 3 December 2023
  • Thumbnail for Histone H2A
    proteins that package DNA into nucleosomes. Histones are responsible for maintaining the shape and structure of a nucleosome. One chromatin molecule is composed...
    17 KB (2,082 words) - 21:32, 11 April 2024
  • Thumbnail for H2AFX
    histones H2A, H2B, H3 and H4, to form chromatin. H2AX contributes to nucleosome-formation, chromatin-remodeling and DNA repair, and is also used in vitro...
    22 KB (2,775 words) - 09:59, 27 March 2024
  • Thumbnail for Skeletal muscle
    tail) in a structure called a nucleosome and one segment of DNA is connected to an adjacent DNA segment on a nucleosome by linker DNA. When histone tails...
    120 KB (13,876 words) - 17:21, 11 May 2024
  • Thumbnail for SWI/SNF
    subfamily provides crucial nucleosome rearrangement, which is seen as ejection and/or sliding. The movement of nucleosomes provides easier access to the...
    37 KB (3,899 words) - 20:41, 6 April 2024
  • Nucleosome Positioning Region Database (NPRD) is a database of nucleosome formation sites (NFSs).[when?] International Society for Computational Biology...
    1 KB (83 words) - 01:22, 30 April 2022
  • Thumbnail for Solenoid (DNA)
    where DNA enters and exits the nucleosome, wrapping 147 base pairs around the histone core and stabilising the nucleosome, this structure is a chromatosome...
    17 KB (2,057 words) - 03:45, 27 December 2023
  • porosome, photosystem I, ATP synthase large DNA and protein complexes: nucleosome centriole and microtubule-organizing center (MTOC) cytoskeleton flagellum...
    28 KB (2,348 words) - 03:23, 19 February 2024