• A nuclear localization signal or sequence (NLS) is an amino acid sequence that 'tags' a protein for import into the cell nucleus by nuclear transport...
    15 KB (2,028 words) - 04:35, 26 April 2024
  • nucleus. It does so by binding to specific recognition sequences, called nuclear localization sequences (NLS). Importin has two subunits, importin α and importin...
    18 KB (2,026 words) - 20:24, 2 April 2024
  • Thumbnail for Dishevelled
    the cytoplasm and nucleus, via a conserved nuclear export sequence (NES) and a nuclear localization sequence (NLS), both necessary for proper functioning...
    12 KB (1,374 words) - 15:08, 1 August 2023
  • Look up localization, L10n, or localize in Wiktionary, the free dictionary. Localization or localisation may refer to: Localization of function, locating...
    3 KB (476 words) - 09:58, 14 March 2024
  • dominant role in recognition of the DR sequences in the transposon. The RED subdomain overlaps with the nuclear localization signal, but its function remains...
    29 KB (2,752 words) - 04:58, 1 April 2024
  • Thumbnail for Nucleoplasm
    Nucleoplasm (redirect from Nuclear sap)
    genes (6784 genes) have been found to localize to the nucleoplasm via targeting by a nuclear localization sequence (NLS). Cytosolic proteins, known as importins...
    16 KB (1,925 words) - 22:37, 21 March 2024
  • Thumbnail for Lamin
    Lamin (redirect from Nuclear lamins)
    the type of lamin. However, all C-terminal domains contain a nuclear localization sequence (NLS). Similar to other IF proteins, lamins self-assemble into...
    18 KB (2,198 words) - 13:06, 31 January 2024
  • Thumbnail for FGF1
    FGF1 can also function intracellularly. The protein has a nuclear localization sequence (NLS) but the route that FGF1 takes to get to the nucleus is...
    20 KB (2,307 words) - 17:41, 12 February 2024
  • Thumbnail for SV40 large T antigen
    protein to study nuclear localization signals (NLSs). It is imported into the nucleus by its interaction with importin α. The NLS sequence is PKKKRKV. SV40...
    12 KB (1,413 words) - 20:11, 3 January 2023
  • Thumbnail for NeuN
    adds a C-terminal PY type nuclear localization sequence, which presumably explains why NeuN/Fox-3 protein can be both nuclear and, in some cell types,...
    8 KB (962 words) - 18:11, 22 January 2023
  • Thumbnail for Importin subunit alpha-1
    "Identification of hSRP1 alpha as a functional receptor for nuclear localization sequences". Science. 268 (5213): 1049–53. Bibcode:1995Sci...268.1049W...
    13 KB (1,632 words) - 12:07, 22 December 2023
  • Thumbnail for IκBα
    the NF-κB transcription factor. IκBα inhibits NF-κB by masking the nuclear localization signals (NLS) of NF-κB proteins and keeping them sequestered in an...
    13 KB (1,526 words) - 18:27, 5 February 2024
  • Thumbnail for G2 phase
    accomplished via removal of nuclear localization sequence (NLS)-obscuring phosphates and phosphorylation of the nuclear export signal. It is thought...
    22 KB (2,818 words) - 04:30, 7 December 2023
  • Thumbnail for Major capsid protein VP1
    icosahedral assembly. The C-terminus also contains a basic nuclear localization sequence,: 316  while the N-terminus - which is oriented toward the center...
    11 KB (1,059 words) - 00:01, 3 December 2023
  • the cytoplasm through the nuclear pore complex using nuclear transport. It has the opposite effect of a nuclear localization signal, which targets a protein...
    10 KB (1,282 words) - 02:21, 23 October 2023
  • releasing the catalytic subunit. The catalytic subunit has a nuclear localization sequence which prompts it to go into the nucleus and phosphorylate other...
    42 KB (5,257 words) - 07:51, 8 May 2024
  • Thumbnail for Guanosine diphosphate
    referred to as the Nuclear Import process, cytosolic proteins like alpha and beta importins would bind the nuclear localization sequence that is located...
    7 KB (701 words) - 15:42, 29 April 2024
  • Thumbnail for Archaea
    known life forms List of Archaea genera List of sequenced archaeal genomes Nuclear localization sequence The Surprising Archaea (book) Towards a natural...
    155 KB (16,478 words) - 20:04, 25 April 2024
  • Thumbnail for Chromosome 5 open reading frame 47
    is predicted to be localized in the nucleus. A stretch of five positively charged lysines, indicating a nuclear localization sequence, can be found at positions...
    17 KB (1,178 words) - 16:55, 4 October 2023
  • Thumbnail for Heterogeneous ribonucleoprotein particle
    mRNA in the cytoplasm. However, hnRNPs also have their own nuclear localization sequences (NLS) and are therefore found mainly in the nucleus. Though...
    17 KB (2,026 words) - 14:57, 11 March 2024
  • bipartite nuclear localization sequence which is the major signal for protein entry into the nucleus. Dingwall C, Laskey RA. Nuclear targeting sequences—a consensus...
    2 KB (266 words) - 01:39, 5 January 2024
  • Thumbnail for Nuclear pore
    of which nuclear localization signal (NLS) are best characterized. Several NLS sequences are known, generally containing a conserved sequence with basic...
    24 KB (2,987 words) - 23:09, 6 April 2024
  • referred to as signal sequence, targeting signal, localization signal, localization sequence, transit peptide, leader sequence or leader peptide) is a...
    15 KB (1,741 words) - 18:05, 31 December 2023
  • Thumbnail for Transportin 1
    This protein is a karyopherin which interacts with nuclear localization sequence to target nuclear proteins to the nucleus. The classical karyopherin...
    12 KB (1,531 words) - 13:22, 23 December 2023
  • Thumbnail for Aryl hydrocarbon receptor
    interacts with carboxyl-terminal of Hsp90 and binds to the AhR nuclear localization sequence (NLS) preventing the inappropriate trafficking of the receptor...
    52 KB (5,962 words) - 15:09, 9 May 2024
  • Thumbnail for IPO4
    (2003). "A Nonconventional Nuclear Localization Signal within the UL84 Protein of Human Cytomegalovirus Mediates Nuclear Import via the Importin α/β...
    4 KB (377 words) - 20:20, 3 March 2023
  • nucleus from the cytoplasm carry nuclear localization signals (NLS) that are bound by importins. An NLS is a sequence of amino acids that acts as a tag...
    8 KB (966 words) - 07:52, 11 February 2024
  • Thumbnail for ORF9b
    the protein is localized to the endoplasmic reticulum (ER) and to intracellular vesicles. It does not have a nuclear localization sequence but can enter...
    8 KB (896 words) - 08:22, 27 April 2024
  • Thumbnail for Rel homology domain
    family. The dimerization subdomain is immediately followed by a nuclear localization sequence that also comprises the site for inhibitory interactions with...
    3 KB (303 words) - 09:34, 30 January 2023
  • Thumbnail for Nuclear medicine
    (1985). "Localization of cortical areas activated by thinking". Journal of Neurophysiology. Vol. 53, no. 5. pp. 1219–1243. "What is nuclear medicine"...
    39 KB (4,408 words) - 06:42, 6 May 2024