• Thumbnail for OPN1LW
    OPN1LW is a gene on the X chromosome that encodes for long wave sensitive (LWS) opsin, or red cone photopigment. It is responsible for perception of visible...
    19 KB (2,372 words) - 18:31, 3 September 2023
  • Thumbnail for Congenital red–green color blindness
    L-opsins expressed by distinct genes, respectively OPN1SW, OPN1MW or OPN1LW. OPN1MW and OPN1LW are located in a gene cluster (along with a locus control region...
    36 KB (3,276 words) - 13:53, 19 March 2024
  • Thumbnail for Cone cell
    and L-cones. Each type expresses a different opsin: OPN1SW, OPN1MW, and OPN1LW, respectively. These cones are sensitive to visible wavelengths of light...
    16 KB (1,938 words) - 15:11, 29 April 2024
  • Thumbnail for Lysine
    rhodopsin and the visual opsins (encoded by the genes OPN1SW, OPN1MW, and OPN1LW), retinaldehyde forms a Schiff base with a conserved lysine residue, and...
    68 KB (7,502 words) - 20:02, 4 May 2024
  • Thumbnail for Squirrel monkey
    genes for colour vision are found on the X chromosome. Typically, one gene (OPN1LW) produces a pigment that is most sensitive to the 564 nm wavelength, while...
    23 KB (2,653 words) - 02:19, 6 April 2024
  • Thumbnail for Color blindness
    and deuteranopia/deuteranomaly. These conditions are mediated by the OPN1LW and OPN1MW genes, respectively, both on the X chromosome. An 'affected'...
    93 KB (10,128 words) - 18:04, 9 May 2024
  • Thumbnail for Cat senses
    most mammals), cats are dichromats with two types of cone opsins, LWS (OPN1LW) and SWS1 (OPN1SW), somewhat similar to a human with protanopia. Cats can...
    20 KB (2,385 words) - 01:45, 15 March 2024
  • Thumbnail for Myopia
    PMC 3740568. PMID 23396134. Neitz M, Neitz J (August 2021). "Intermixing the OPN1LW and OPN1MW Genes Disrupts the Exonic Splicing Code Causing an Array of Vision...
    88 KB (9,241 words) - 12:43, 6 May 2024
  • Thumbnail for Monochromacy
    [citation needed] A recent study using through PCR analysis of genes OPN1SW, OPN1LW, and PDE6C determined that all mammals in the cohort Xenarthra (representing...
    12 KB (1,452 words) - 20:27, 5 February 2024
  • Thumbnail for Evolution of color vision in primates
    most sensitive to green light L-opsin (long wave sensitive, encoded by OPN1LW gene), the cone most sensitive to red light The taxa Platyrhini includes...
    31 KB (3,830 words) - 09:07, 2 April 2024
  • Thumbnail for Retinal
    cytoplasm of the cell. The opsins in the cone cells are OPN1SW, OPN1MW, and OPN1LW. The cones form incomplete disks that are part of the plasma membrane, so...
    33 KB (3,311 words) - 12:09, 26 April 2024
  • or atypical achromatopsia. BCM stems from mutations or deletions of the OPN1LW and OPN1MW genes, both on the X chromosome. As a recessive x-linked condition...
    26 KB (2,928 words) - 00:54, 8 April 2024
  • Thumbnail for Opsin
    humans with 3 photopsins in 2 classes: SWS1 (OPN1SW) and two forms of LWS (OPN1LW, OPN1MW). Scotopsins - those responsible for scotopic vision (dim light)...
    83 KB (8,995 words) - 09:17, 2 April 2024
  • Thumbnail for Vertebrate visual opsin
    Abbr. Cell λmax (nm) Human variant Long-wave sensitive LWS Cone 500–570 OPN1LW "red" erythrolabe (564nm) OPN1MW "green" chlorolabe (534nm) Short-wave sensitive 1...
    10 KB (1,042 words) - 16:05, 2 May 2024
  • Thumbnail for Color vision
    encoding of these leads to the two most common forms of color blindness. The OPN1LW gene, which encodes the opsin present in the L cones, is highly polymorphic;...
    64 KB (7,831 words) - 19:37, 14 April 2024
  • Thumbnail for Rhodopsin-like receptors
    Opsin 1 (cone pigments), long-wave-sensitive (color blindness, protan) (OPN1LW, OPSR) (red-sensitive opsin) Opsin 3, Panopsin (OPN3) Opsin 4, Melanopsin...
    25 KB (2,172 words) - 01:01, 29 November 2023
  • opsins (LWS or MWS) is expressed exclusively in each cone. LWS opsin 300822 OPN1LW Xq28 Encodes the LWS (red) photopsin protein. MWS opsin 300821 OPN1MW Xq28...
    19 KB (2,153 words) - 11:41, 22 March 2024
  • administration for blue-cone monochromacy by delivering a functional copy of the OPN1LW gene. In September 2022, Adverum announced that its first patient was dosed...
    8 KB (594 words) - 23:34, 13 February 2024
  • Thumbnail for Melanopsin
    brain regions, the pineal gland, and the skin. Paralogs of Opn4 include OPN1LW, OPN1MW, rhodopsin and encephalopsin. Melanopsin, like all other animal...
    39 KB (4,525 words) - 07:01, 5 April 2024
  • Q14982 11079 OPHN1 HGNC:8148 O60890 11080 OPLAH HGNC:8149 O14841 11081 OPN1LW HGNC:9936 P04000 11082 OPN1MW HGNC:4206 P04001 11083 OPN1MW2 HGNC:26952...
    282 KB (17 words) - 23:17, 27 April 2024
  • (adult) There is an opsin LCR (OPSIN-LCR) controlling the expression of OPN1LW and the first copies of OPN1MW on the human X chromosome, upstream of these...
    8 KB (899 words) - 22:05, 3 June 2022
  • carriers of color blindness. Carriers will have one opsin gene (OPN1MW or OPN1LW) with differing alleles thereof on each chromosome, such that the alleles...
    3 KB (342 words) - 10:01, 30 December 2023
  • Blue cone monochromacy; 303700; OPN1MW Blue cone monochromacy; 303700; OPN1LW Boomerang dysplasia; 112310; FLNB Börjeson–Forssman–Lehmann syndrome; 301900;...
    234 KB (18,877 words) - 15:43, 9 May 2024