• Thumbnail for Occludin
    Occludin is a transmembrane protein that regulates the permeability of epithelial and endothelial barriers. It was first identified in epithelial cells...
    24 KB (2,896 words) - 01:50, 26 March 2024
  • Thumbnail for Tight junction
    transmembrane and cytoplasmic proteins. The three major transmembrane proteins are occludin, claudins, and junction adhesion molecule (JAM) proteins. These associate...
    14 KB (1,531 words) - 14:26, 7 May 2024
  • Thumbnail for Tight junction protein 1
    F11 receptor, GJA3, GJA8, Gap junction protein, alpha 1, KIRREL, MLLT4, Occludin, TJP3, and Tight junction protein 2. Tight junction ENSG00000104067 GRCh38:...
    16 KB (2,033 words) - 19:34, 28 January 2023
  • Thumbnail for Claudin
    Claudins are a family of proteins which, along with occludin, are the most important components of the tight junctions (zonulae occludentes). Tight junctions...
    11 KB (1,256 words) - 07:26, 10 February 2024
  • mutant occludin in epithelial cells leads to break down the barrier function of tight junction and changes in a migration of neutrophils. Occludin cooperates...
    14 KB (1,909 words) - 21:56, 31 December 2023
  • Thumbnail for Blood–brain barrier
    which are composed of smaller subunits of transmembrane proteins, such as occludin, claudins (such as Claudin-5), junctional adhesion molecule (such as JAM-A)...
    33 KB (3,699 words) - 22:13, 20 April 2024
  • Thumbnail for Neural crest
    initially anchored to neighboring cells by tight junction proteins such as occludin and cell adhesion molecules such as NCAM and N-Cadherin. Dorsally expressed...
    41 KB (4,584 words) - 16:09, 24 February 2024
  • Thumbnail for MMP3
    mice were shown to have lower claudin-5 and occludin levels than the KO mice after TBI. Claudin and occludin are proteins that are essential for the formation...
    26 KB (3,031 words) - 10:50, 15 January 2024
  • Thumbnail for Cell junction
    targeting. Transmembrane proteins – including junctional adhesion molecule, occludin, and claudin. It is believed that claudin is the protein molecule responsible...
    20 KB (2,248 words) - 17:32, 2 May 2024
  • Thumbnail for Hepatitis C virus
    cell-surface molecules CD81, LDL receptor, SR-BI, DC-SIGN, Claudin-1, and Occludin. The envelope of HCV is similar to very low-density lipoproteins (VLDL)...
    54 KB (6,585 words) - 09:53, 7 March 2024
  • Thumbnail for Tight junction protein 2
    2 has been shown to interact with tight junction protein 1, band 4.1, occludin and USP53. GRCh38: Ensembl release 89: ENSG00000119139 – Ensembl, May 2017...
    10 KB (1,201 words) - 04:08, 22 January 2024
  • epithelial features, by stopping the expression of occludin, a tight junction protein. Loss of occludin causes a loss of the previous tight junction seals...
    18 KB (2,122 words) - 17:09, 23 February 2024
  • Thumbnail for Calu-3
    ERBB2 gene, leading to active ErbB2/Her2. The cells also express CK7, occludin, and E-cadherin. Calu-3 cells also have large amounts of cystic fibrosis...
    3 KB (429 words) - 00:54, 8 November 2023
  • Thumbnail for Cell adhesion
    Tight junction is formed by transmembrane proteins, including claudins, occludins and tricellulins, that bind closely to each other on adjacent membranes...
    32 KB (3,661 words) - 14:55, 18 January 2024
  • Thumbnail for Intestinal epithelium
    function. These complexes, formed primarily of members of the claudin and the occludin families, consist of about 35 different proteins, form a ring shaped continuous...
    27 KB (3,041 words) - 16:01, 7 April 2024
  • permiability and the expression of tightly bound proteins - e-cadherin and occludin. Both of them increase the tight junctions between cells, strengthen the...
    24 KB (2,533 words) - 19:27, 13 February 2024
  • Thumbnail for Primary familial brain calcification
    associated with this condition are Junctional adhesion molecule C (JAM3) and Occludin (OCLN).[citation needed] The most commonly affected region of the brain...
    19 KB (2,148 words) - 11:02, 22 April 2024
  • up of many different proteins. The four main transmembrane proteins are occludin, claudin, junctional adhesion molecules (JAMs) and tricellulins. The extracellular...
    17 KB (2,219 words) - 12:38, 6 February 2024
  • Thumbnail for Actinidain
    of kiwifruit (Actinidia deliciosa) cysteine protease actinidin on the occludin tight junction network in T84 intestinal epithelial cells". Food and Chemical...
    16 KB (1,922 words) - 15:42, 27 November 2023
  • malocclusion, nondisclosure, nonexclusive, noninclusive, nonocclusion, occlude, occludin, occlusion, occlusive, preclude, preclusion, preclusive, predisclose, predisclosure...
    250 KB (126 words) - 12:30, 3 April 2024
  • DNA, microtubules, intermediate filaments, tight junctions (including occludins and claudins), adherens junctions, and cadherins. January 25, 1955: Publication...
    24 KB (2,955 words) - 07:04, 6 March 2024
  • Thumbnail for Catenin beta-1
    Gupta A (December 2002). "Tyrosine phosphorylation and dissociation of occludin-ZO-1 and E-cadherin-beta-catenin complexes from the cytoskeleton by oxidative...
    107 KB (12,345 words) - 09:19, 30 April 2024
  • Thumbnail for SNAI1
    epithelium-mesenchyme transition: direct repression of the gene expression of claudins/occludin by Snail". Journal of Cell Science. 116 (Pt 10): 1959–67. doi:10.1242/jcs...
    15 KB (1,850 words) - 18:01, 23 December 2023
  • Thumbnail for Cingulin
    II and several TJ proteins including ZO-1, ZO-2, ZO-3, paracingulin and occludin. Moreover, cingulin forms a complex with JAM-A, a tight junction membrane...
    17 KB (2,075 words) - 20:25, 26 March 2024
  • Thumbnail for Peripheral myelin protein 22
    or transection. PMP22 has shown association with zonula-occludens 1 and occludin, proteins that are involved in adhesion with other cells and the extracellular...
    12 KB (1,472 words) - 15:34, 9 December 2023
  • Thumbnail for OCEL1
    OCEL1, also called Occludin//ELL Domain Containing 1, is a protein encoding gene located at chromosome 19p13.11 in the human genome. Other aliases for...
    14 KB (1,572 words) - 02:17, 28 March 2024
  • Epithelial-associated genes such as E-cadherin/Cdh1, Cldns −3, −4, −7, −11, Occludin (Ocln), Epithelial cell adhesion molecule (Epcam), and Crumbs homolog 3...
    14 KB (1,600 words) - 04:00, 19 August 2023
  • (2010). Ovarian hormones control the changing expression of claudins and occludin in rat uterine epithelial cells during early pregnancy. Acta histochemica...
    12 KB (1,667 words) - 00:33, 5 November 2021
  • Thumbnail for Aicardi–Goutières syndrome
    "Recessive mutations in the gene encoding the tight junction protein occludin cause band-like calcification with simplified gyration and polymicrogyria"...
    30 KB (3,342 words) - 18:10, 18 April 2024
  • Thumbnail for Pathophysiology of multiple sclerosis
    to normal endothelial cells, the cells lining the BBB are connected by occludin and claudin which form tight junctions in order to create a barrier to...
    76 KB (9,023 words) - 04:22, 25 March 2024