• In molecular biology, origin recognition complex (ORC) is a multi-subunit DNA binding complex (6 subunits) that binds in all eukaryotes and archaea in...
    21 KB (2,335 words) - 13:22, 16 August 2023
  • Thumbnail for Eukaryotic DNA replication
    assembly of the pre-replication complex (pre-RC) is the binding of the origin recognition complex (ORC) to the replication origin. In late mitosis, the Cdc6...
    119 KB (14,643 words) - 16:04, 26 April 2024
  • Thumbnail for Origin of replication
    Zhao Y, et al. (July 2018). "Structure of the origin recognition complex bound to DNA replication origin". Nature. 559 (7713): 217–222. Bibcode:2018Natur...
    113 KB (12,563 words) - 01:23, 21 April 2024
  • Thumbnail for DNA replication
    associate with the bound origin recognition complex at the origin in order to form a larger complex necessary to load the Mcm complex onto the DNA. In eukaryotes...
    60 KB (7,306 words) - 20:48, 25 March 2024
  • Thumbnail for Pre-replication complex
    simplified model of the eukaryotic pre-RC. It is composed of a single origin recognition complex (ORC) protein, Cdc6/ORC1, and a homohexamer of the minichromosome...
    15 KB (1,928 words) - 17:24, 8 January 2024
  • proteins to disrupt the H-bonding in that area. ORC protein complex (origin recognition complex) is bound at the ARS throughout the cell cycle, allowing...
    2 KB (312 words) - 20:27, 29 January 2023
  • Thumbnail for ORC1
    Origin recognition complex subunit 1 is a protein that in humans is encoded by the ORC1 gene. It is closely related to CDC6, and both are the same protein...
    12 KB (1,433 words) - 06:31, 27 December 2023
  • Thumbnail for ORC2
    Origin recognition complex subunit 2 is a protein that is encoded by the ORC2 (ORC2L) gene in humans. The origin recognition complex (ORC) is a highly...
    13 KB (1,480 words) - 02:27, 29 March 2023
  • Thumbnail for ORC4
    Origin recognition complex subunit 4 is a protein that in humans is encoded by the ORC4 (ORC4L) gene. The origin recognition complex (ORC) is a highly...
    9 KB (1,126 words) - 19:06, 26 April 2024
  • Thumbnail for DNA unwinding element
    by origin recognition complex. DUEs are found in both prokaryotic and eukaryotic organisms, but were first discovered in yeast and bacteria origins, by...
    18 KB (2,303 words) - 14:39, 3 December 2023
  • Thumbnail for Bik Kwoon Tye
    the first high-resolution structures of both the MCM complex and the Origin Recognition Complex (ORC) in 2015 and 2018. Tye is currently a Professor Emeritus...
    17 KB (2,058 words) - 01:54, 3 September 2023
  • Thumbnail for ORC3
    Origin recognition complex subunit 3 is a protein that in humans is encoded by the ORC3 (ORC3L) gene. The origin recognition complex (ORC) is a highly...
    9 KB (974 words) - 23:29, 3 March 2023
  • Thumbnail for ORC6
    Origin recognition complex subunit 6 is a protein that in humans is encoded by the ORC6 (ORC6L) gene. The origin recognition complex (ORC) is a highly...
    9 KB (881 words) - 16:49, 28 October 2022
  • Thumbnail for ORC5
    Origin recognition complex subunit 5 is a protein that in humans is encoded by the ORC5 (ORC5L) gene. The origin recognition complex (ORC) is a highly...
    8 KB (983 words) - 23:58, 3 March 2023
  • independently replicated from a single origin of replication[citation needed]. A bacterial chromosome contains a single origin, and therefore the whole bacterial...
    6 KB (634 words) - 22:52, 2 December 2023
  • union Organic Rankine Cycle Organized retail crime Origin recognition complex, a protein complex Otago Regional Council, New Zealand Ottawa Rowing Club...
    2 KB (264 words) - 16:21, 14 April 2024
  • Thumbnail for DNA replication factor CDT1
    pre-replication complexes (pre-RC), which occurs during the G1 phase of the cell cycle. In the assembly of pre-RCs, origin recognition complexes (ORC1-6) recognize...
    12 KB (1,439 words) - 23:24, 9 May 2024
  • Thumbnail for ChIP-on-chip
    are transcription factors, replication-related proteins, like origin recognition complex protein (ORC), histones, their variants, and histone modifications...
    25 KB (3,057 words) - 05:34, 12 December 2023
  • Thumbnail for Cell cycle
    Cellular model Eukaryotic DNA replication Mitotic catastrophe Origin recognition complex Retinoblastoma protein Synchronous culture – synchronization of...
    77 KB (8,991 words) - 15:41, 30 March 2024
  • Thumbnail for Kinetochore
    Bub1, Bub3, Mad2 and CENP-E. Orc2 (a protein that belongs to the origin recognition complex -ORC- implicated in DNA replication initiation during S phase)...
    65 KB (7,831 words) - 03:32, 6 January 2024
  • Thumbnail for Replisome
    Efficient replisome assembly at origins of replication (origin recognition complexes or specific replication origin sequences in some organisms) Separating...
    32 KB (3,700 words) - 00:38, 1 January 2024
  • Thumbnail for Anaphase-promoting complex
    protein that binds to Cdt1 which prevents its binding to the origin recognition complex (ORC). APCCdh1 targets geminin for ubiquitination throughout G1...
    31 KB (4,181 words) - 06:10, 4 May 2024
  • Thumbnail for Minichromosome maintenance
    Site selection for replication origins is carried out by the Origin Recognition Complex (ORC), a six subunit complex (Orc1-6). During the G1 phase of...
    24 KB (3,042 words) - 22:16, 29 October 2022
  • Thumbnail for BAH domain
    proteins such as eukaryotic DNA (cytosine-5) methyltransferases, the origin recognition complex 1 (Orc1) proteins, Bromo adjacent homology domain containing 1...
    2 KB (146 words) - 21:34, 18 August 2023
  • Thumbnail for Polytene chromosome
    with the active chromatin proteins, nucleosome remodeling, and origin recognition complexes. Their primary functions are: to act as binding sites for RNA...
    16 KB (1,980 words) - 00:24, 31 October 2023
  • Thumbnail for DnaA
    unwinding of origin DNA for precise timing. DnaA recognition sites in Escherichia coli are arranged in OriC to facilitate staged pre-replication complex assembling...
    19 KB (2,272 words) - 01:50, 3 December 2023
  • Thumbnail for CDC6
    of Human Origin Recognition Complex, Cdc6, and Minichromosome Maintenance Proteins during the Cell Cycle: Assembly of Prereplication Complexes in Late...
    11 KB (1,361 words) - 19:13, 13 August 2023
  • Thumbnail for RRM3
    in Rrm3p code for a region that binds to Orc5, a domain in an origin recognition complex. The binding of these two proteins appears to be linked to inappropriate...
    16 KB (2,033 words) - 01:35, 3 December 2023
  • methyltransferase, methyl CpG binding protein MeCP2, and the origin recognition complex protein ORC2. HP1 has a versatile structure with three main components;...
    16 KB (1,880 words) - 20:36, 13 October 2022
  • Thumbnail for Armenian genocide recognition
    Armenian genocide recognition is the formal acceptance that the systematic massacres and forced deportation of Armenians committed by the Ottoman Empire...
    256 KB (24,336 words) - 11:03, 28 April 2024