• Thumbnail for Osteoblast
    Osteoblasts (from the Greek combining forms for "bone", ὀστέο-, osteo- and βλαστάνω, blastanō "germinate") are cells with a single nucleus that synthesize...
    34 KB (3,988 words) - 11:31, 24 March 2024
  • Thumbnail for Bone
    Bone (section Osteoblast)
    bone rigidity. Bone tissue is made up of different types of bone cells. Osteoblasts and osteocytes are involved in the formation and mineralisation of bone;...
    76 KB (8,827 words) - 21:44, 29 April 2024
  • Thumbnail for Osteocyte
    some of which differentiate into active osteoblasts (which may further differentiate to osteocytes). Osteoblasts/osteocytes develop in mesenchyme. In mature...
    23 KB (2,520 words) - 19:16, 20 September 2023
  • Thumbnail for RUNX2
    by the RUNX2 gene. RUNX2 is a key transcription factor associated with osteoblast differentiation. It has also been suggested that Runx2 plays a cell proliferation...
    19 KB (2,246 words) - 22:36, 11 April 2024
  • inactive, osteoblast are at peak activity. Likewise, at pH 6.9 osteoblast activity is non-existent. The hormone estrogen is also important for osteoblast regulation...
    17 KB (2,107 words) - 06:03, 4 February 2024
  • Thumbnail for Adrenocorticotropic hormone
    glands, it is also expressed elsewhere in the body, specifically in the osteoblast, which is responsible for making new bone, a continual and highly regulated...
    16 KB (1,707 words) - 01:32, 21 April 2024
  • Thumbnail for Intramembranous ossification
    stem cell, or MSC, is an unspecialized cell that can develop into an osteoblast. Before it begins to develop, the morphological characteristics of a MSC...
    9 KB (965 words) - 19:43, 25 October 2023
  • Thumbnail for Osteoid
    of the bone matrix that forms prior to the maturation of bone tissue. Osteoblasts begin the process of forming bone tissue by secreting the osteoid as...
    3 KB (376 words) - 13:23, 1 February 2024
  • Thumbnail for Ossification
    remodeling is the process of laying down new bone material by cells named osteoblasts. It is synonymous with bone tissue formation. There are two processes...
    7 KB (691 words) - 17:18, 27 November 2023
  • Thumbnail for Cellular differentiation
    performing essentially as stem cells—could then redifferentiate into osteoblasts and adipocytes. Each specialized cell type in an organism expresses a...
    50 KB (6,014 words) - 20:21, 19 February 2024
  • Thumbnail for Mesenchymal stem cell
    cells that can differentiate into a variety of cell types, including osteoblasts (bone cells), chondrocytes (cartilage cells), myocytes (muscle cells)...
    43 KB (4,861 words) - 16:53, 22 February 2024
  • Thumbnail for Hydrochlorothiazide
    promoting calcium retention in the kidney, and by directly stimulating osteoblast differentiation and bone mineral formation. The combination of fixed-dose...
    25 KB (2,187 words) - 19:29, 28 March 2024
  • Thumbnail for Bone healing
    mineralized matrix is penetrated by microvessel and numerous osteoblasts. The osteoblasts form new lamellar bone upon the recently exposed surface of the...
    17 KB (2,052 words) - 21:46, 29 April 2024
  • Thumbnail for Bone remodeling
    events. Two main types of cells are responsible for bone metabolism: osteoblasts (which secrete new bone), and osteoclasts (which break bone down). The...
    5 KB (521 words) - 03:49, 14 April 2024
  • miR-764-5p sequence is upregulated during osteoblast differentiation in both skull-specific calvarial and osteoblast progenitor cells. The channel-forming...
    2 KB (182 words) - 19:15, 28 August 2023
  • Thumbnail for Bistability
    progenitor ( z {\displaystyle z} ), osteoblast ( y {\displaystyle y} ), and chondrocyte ( x {\displaystyle x} ). Pro-osteoblast stimulus promotes P→O transition...
    20 KB (2,447 words) - 18:16, 26 November 2023
  • research on osteoblast (bone-forming cells) response to hydroxyapatite doped with divalent and trivalent cations showed that osteoblast adherence and...
    26 KB (2,259 words) - 12:42, 13 April 2024
  • Thumbnail for Periosteum
    highly cellular containing progenitor cells that develop into osteoblasts. These osteoblasts are responsible for increasing the width of a long bone (the...
    5 KB (497 words) - 05:50, 24 April 2024
  • Thumbnail for Periostin
    Periostin (POSTN, PN, or osteoblast-specific factor OSF-2) is a protein that in humans is encoded by the POSTN gene. Periostin functions as a ligand for...
    19 KB (2,287 words) - 14:40, 8 April 2024
  • Thumbnail for Skeleton
    compression while staying lightweight. Most cells in bones are either osteoblasts, osteoclasts, or osteocytes. Bone tissue is a type of dense connective...
    31 KB (3,602 words) - 00:44, 13 March 2024
  • Osteoblast milk protein (OMP, Chinese: 造骨牛奶蛋白) is the name used by Mengniu, a Chinese dairy company, for a milk protein used as a food additive in their...
    7 KB (677 words) - 15:40, 6 October 2023
  • Thumbnail for Endosteum
    periosteal surface. During bone growth, the width of the bone increases as osteoblasts lay new bone tissue at the periosteum. To prevent the bone from becoming...
    2 KB (172 words) - 00:29, 5 August 2023
  • Thumbnail for Adenosine receptor
    Similarly to A2A receptor, the A2B receptor promotes osteoblast differentiation. The osteoblast cell is derived from the Mesenchymal Stem Cell (MSC) which...
    20 KB (1,954 words) - 16:46, 22 April 2024
  • Thumbnail for Bone resorption
    lysosomes. These are the cells responsible for the resorption of bone. Osteoblasts are generally present on the outer layer of bone, just beneath the periosteum...
    19 KB (2,218 words) - 23:56, 31 October 2023
  • Thumbnail for Parathyroid hormone-related protein
    PTHrP produced by osteoblasts is a physiological regulator of bone formation. Martin and Miao et al. demonstrated that osteoblast-specific ablation of...
    20 KB (2,385 words) - 18:42, 21 August 2023
  • Thumbnail for Osteoclast
    origin was popular, which stated that osteoclasts and osteoblasts are of the same lineage, and osteoblasts fuse together to form osteoclasts. After years of...
    26 KB (2,925 words) - 01:53, 25 March 2024
  • Thumbnail for Extracellular matrix
    Chondrocytes are found in cartilage and produce the cartilaginous matrix. Osteoblasts are responsible for bone formation. The ECM can exist in varying degrees...
    36 KB (4,086 words) - 05:30, 9 March 2024
  • Thumbnail for Osteoprotegerin
    pre-eclampsia and osteoporosis during pregnancy. OPG is largely expressed by osteoblast lineage cells of bone, epithelial cells of the gastrointestinal tract...
    30 KB (3,686 words) - 09:12, 11 December 2023
  • Thumbnail for Sarcoma
    Osteoblast Osteoid osteoma Osteoblastoma Osteoma/osteosarcoma Chondroblast Chondroma/ecchondroma/enchondroma Enchondromatosis Extraskeletal chondroma Chondrosarcoma...
    35 KB (3,903 words) - 02:28, 27 March 2024
  • Thumbnail for Flat bone
    space in the ring of osteoblasts, and eventually fills the bony matrix. After the bone is completely ossified, the osteoblasts retract their calcium...
    4 KB (523 words) - 08:38, 19 March 2024