• Thumbnail for PAX7
    Paired box protein Pax-7 is a protein that in humans is encoded by the PAX7 gene. Pax-7 plays a role in neural crest development and gastrulation, and...
    11 KB (1,377 words) - 09:34, 24 December 2023
  • Thumbnail for PAX3
    are present in a subfamily along with the highly homologous human PAX7 and mouse Pax7 genes. The human PAX3 gene is located in the 2q36.1 chromosomal region...
    35 KB (4,371 words) - 10:33, 20 January 2024
  • associated with ARMS, but are not necessary, PAX3-FKHR (now known as FOXO1). and PAX7-FKHR. In children and adolescents ARMS accounts for about 1 percent of all...
    11 KB (1,302 words) - 06:32, 1 December 2023
  • Thumbnail for Myogenesis
    complete absence of forelimb muscles. Associated genetic factors: PAX7 Mutations in Pax7 will prevent the formation of satellite cells and, in turn, prevent...
    23 KB (2,640 words) - 10:26, 17 January 2024
  • activation results in the progressive loss of Pax7 expression as they enter the proliferative stage. However, Pax7 is expressed prominently after satellite...
    28 KB (3,408 words) - 17:26, 22 February 2024
  • Thumbnail for Pax genes
    usually a partial, or in the case of four family members (PAX3, PAX4, PAX6 and PAX7), a complete homeodomain to the C-terminus. An octapeptide as well as a Pro-Ser-Thr-rich...
    10 KB (1,191 words) - 01:21, 10 March 2024
  • Thumbnail for Hard palate
    several genetic risk factors. Six single-nucleotide polymorphisms in the PAX7 gene are implicated in the development of facial features. These variations...
    8 KB (963 words) - 22:08, 2 December 2023
  • Thumbnail for Down syndrome
    liposarcoma t(12 DDIT3; 16 FUS) Desmoplastic small-round-cell tumor t(11 WT1; 22 EWS) Alveolar rhabdomyosarcoma t(2 PAX3; 13 FOXO1) t (1 PAX7; 13 FOXO1)...
    143 KB (14,330 words) - 21:57, 18 April 2024
  • Thumbnail for Birth defect
    liposarcoma t(12 DDIT3; 16 FUS) Desmoplastic small-round-cell tumor t(11 WT1; 22 EWS) Alveolar rhabdomyosarcoma t(2 PAX3; 13 FOXO1) t (1 PAX7; 13 FOXO1)...
    95 KB (10,063 words) - 13:47, 9 March 2024
  • Thumbnail for Turner syndrome
    liposarcoma t(12 DDIT3; 16 FUS) Desmoplastic small-round-cell tumor t(11 WT1; 22 EWS) Alveolar rhabdomyosarcoma t(2 PAX3; 13 FOXO1) t (1 PAX7; 13 FOXO1)...
    77 KB (9,090 words) - 08:13, 28 April 2024
  • Thumbnail for Miscarriage
    liposarcoma t(12 DDIT3; 16 FUS) Desmoplastic small-round-cell tumor t(11 WT1; 22 EWS) Alveolar rhabdomyosarcoma t(2 PAX3; 13 FOXO1) t (1 PAX7; 13 FOXO1)...
    111 KB (10,922 words) - 12:30, 26 March 2024
  • Thumbnail for Rhabdomyosarcoma
    Both involve the translocation of a DNA binding domain of either PAX3 or PAX7, a member of the Paired Box family of transcription factors, to a transactivation...
    50 KB (5,950 words) - 11:58, 30 January 2024
  • Thumbnail for Homeobox
    LEUTX; MIXL1; NOBOX; OTP; OTX1, OTX2, CRX; PAX2, PAX3, PAX4, PAX5, PAX6, PAX7, PAX8; PHOX2A, PHOX2B; PITX1, PITX2, PITX3; PROP1; PRRX1, PRRX2; RAX, RAX2;...
    42 KB (4,469 words) - 17:00, 1 April 2024
  • Thumbnail for Neurula
    functionality. Within chicks, frogs and fish Pax3/Pax7 are activated by Wnt and FGF signaling. Pax3 and Pax7 are also required for neural crest induction after...
    16 KB (1,951 words) - 16:05, 1 November 2023
  • Thumbnail for Gooseberry (gene)
    and PAX7 in clinical settings. This is attributed to the gooseberry genes gsb-proximal and gsb-distal showing similar function to PAX3 and PAX7. Waardenburg...
    16 KB (1,669 words) - 13:57, 31 March 2024
  • Thumbnail for Sonic hedgehog protein
    transcription factors—Nkx2.2, Olig2, Nkx6.1, Nkx6.2, Dbx1, Dbx2, Irx3, Pax6, and Pax7—that is regulated by the SHH gradient. These transcription factors are induced...
    62 KB (7,133 words) - 18:41, 9 March 2024
  • Paired box Known motif – High-throughput in vitro [679] YACGCHYSRNYRMNY PAX7 ENSG00000009709 Homeodomain; Paired box Known motif – High-throughput in...
    374 KB (81 words) - 02:10, 23 September 2023
  • Sarasa M; Domínguez L (August 2005). "Novel expression patterns of Pax3/Pax7 in early trunk neural crest and its melanocyte and non-melanocyte lineages...
    2 KB (271 words) - 11:30, 29 November 2023
  • Thumbnail for Neural plate
    specifiers are induced as a set of transcription factors. Distalless-5, PAX3 and PAX7 prevent the border region from becoming either neural plate or epidermis...
    18 KB (2,459 words) - 15:20, 7 February 2024
  • Thumbnail for Facioscapulohumeral muscular dystrophy
    genes involved in muscle development, including MyoD, myogenin, desmin, and PAX7, and indeed DUX4 expression has shown to reduce muscle cell proliferation...
    174 KB (16,335 words) - 04:50, 29 April 2024
  • HGNC:8618 O43316 11753 PAX5 HGNC:8619 Q02548 11754 PAX6 HGNC:8620 P26367 11755 PAX7 HGNC:8621 P23759 11756 PAX8 HGNC:8622 Q06710 11757 PAX9 HGNC:8623 P55771...
    282 KB (17 words) - 23:17, 27 April 2024
  • notochord, fin, and muscle The blastema that is formed expresses PAX3 and PAX7, which is associated with activation of muscle stem cells.  This specific...
    23 KB (2,692 words) - 23:19, 17 March 2024
  • Embryonal rhabdomyosarcoma can be classified by its lack of PAX3–FOXO1 or PAX7–FOXO1 gene fusions, but approximately 20% of alveolar rhabdomyosarcomas are...
    34 KB (3,763 words) - 20:53, 6 January 2024
  • Thumbnail for Polysomy
    liposarcoma t(12 DDIT3; 16 FUS) Desmoplastic small-round-cell tumor t(11 WT1; 22 EWS) Alveolar rhabdomyosarcoma t(2 PAX3; 13 FOXO1) t (1 PAX7; 13 FOXO1)...
    39 KB (4,295 words) - 19:58, 17 April 2024
  • liposarcoma t(12 DDIT3; 16 FUS) Desmoplastic small-round-cell tumor t(11 WT1; 22 EWS) Alveolar rhabdomyosarcoma t(2 PAX3; 13 FOXO1) t (1 PAX7; 13 FOXO1)...
    21 KB (1,923 words) - 22:34, 2 January 2024
  • liposarcoma t(12 DDIT3; 16 FUS) Desmoplastic small-round-cell tumor t(11 WT1; 22 EWS) Alveolar rhabdomyosarcoma t(2 PAX3; 13 FOXO1) t (1 PAX7; 13 FOXO1)...
    14 KB (1,341 words) - 22:41, 10 April 2024
  • Thumbnail for MyoD
    induce cells in somites that receive these Wnt signals to express Pax3 and Pax7 in addition to myogenic regulatory factors, including Myf5 and MyoD. Specifically...
    27 KB (3,405 words) - 21:56, 6 November 2022
  • onset of myogenesis in the embryo. They discovered a population of Pax3/Pax7-positive progenitors that are essential for foetal muscle development and...
    16 KB (1,578 words) - 21:01, 8 November 2023
  • translocations including translocation of the FOXO1 gene fusing with the PAX3 or PAX7 gene. In the neuroectodermal component of the tumors, neuroblastic neoplasm...
    12 KB (1,313 words) - 00:50, 20 February 2023
  • liposarcoma t(12 DDIT3; 16 FUS) Desmoplastic small-round-cell tumor t(11 WT1; 22 EWS) Alveolar rhabdomyosarcoma t(2 PAX3; 13 FOXO1) t (1 PAX7; 13 FOXO1)...
    11 KB (1,105 words) - 12:55, 17 October 2023