The PHLPP isoforms (PH domain and Leucine rich repeat Protein Phosphatases) are a pair of protein phosphatases, PHLPP1 and PHLPP2, that are important...
12 KB (1,431 words) - 17:47, 28 October 2022
repeat protein phosphatase, also known as PHLPP, is an enzyme which in humans is encoded by the PHLPP gene. PHLPP GRCh38: Ensembl release 89: ENSG00000081913...
4 KB (490 words) - 08:58, 8 January 2024
phosphatases dephosphorylate PIP3 to form PIP2. The phosphatases in the PHLPP family, PHLPP1 and PHLPP2 have been shown to directly de-phosphorylate,...
34 KB (3,754 words) - 20:14, 23 April 2024
phosphatase 2A (PP2A), which dephosphorylates Akt at Thr308 and phosphatase PHLPP dephosphorylates Akt at Ser473. Another protein important in Akt attenuation...
37 KB (4,116 words) - 05:18, 11 December 2023
important discoveries in the protein phosphatase field, discovering and naming PHLPP (PH domain and Leucine rich repeat Protein Phosphatases), which regulate...
12 KB (1,196 words) - 10:56, 20 June 2023
as PHLPPL, is an enzyme which in humans is encoded by the PHLPPL gene. PHLPP GRCh38: Ensembl release 89: ENSG00000040199 – Ensembl, May 2017 GRCm38:...
4 KB (514 words) - 15:24, 28 October 2022
OSBPL5, OSBPL6, OSBPL7, OSBPL8, OSBPL9, PHLDA2, PHLDA3, PHLDB1, PHLDB2, PHLPP, PIP3-E, PLCD1, PLCD4, PLCG1, PLCG2, PLCH1, PLCH2, PLCL1, PLCL2, PLD1, PLD2...
14 KB (1,434 words) - 21:33, 2 February 2024
Castranova V, Shi X, Chen F (October 2011). "miR-190-mediated downregulation of PHLPP contributes to arsenic-induced Akt activation and carcinogenesis". Toxicological...
5 KB (521 words) - 00:30, 3 December 2023