• Thumbnail for PIEZO1
    PIEZO1 is a mechanosensitive ion channel protein that in humans is encoded by the gene PIEZO1. PIEZO1 and its close homolog PIEZO2 were cloned in 2010...
    13 KB (1,345 words) - 00:15, 24 February 2024
  • Thumbnail for Ardem Patapoutian
    laureate of Armenian descent. He is known for his work in characterizing the PIEZO1, PIEZO2, and TRPM8 receptors that detect pressure, menthol, and temperature...
    32 KB (2,464 words) - 13:51, 19 April 2024
  • Thumbnail for Yoda1
    which is the first agonist developed for the mechanosensitive ion channel PIEZO1. This protein is involved in regulation of blood pressure and red blood...
    5 KB (390 words) - 15:44, 12 April 2024
  • Thumbnail for Epithelium
    2017). "Mechanical stretch triggers rapid epithelial cell division through Piezo1". Nature. 543 (7643): 118–121. Bibcode:2017Natur.543..118G. doi:10.1038/nature21407...
    32 KB (2,885 words) - 09:03, 22 April 2024
  • Thornton, Nicole M (19 September 2022). "Missense mutations in PIEZO1, encoding the Piezo1 mechanosensor protein, define the Er red blood cell antigens"...
    21 KB (1,374 words) - 03:13, 10 February 2024
  • from the Greek πιέζω, which means to squeeze or press, and may refer to: PIEZO1, a mechanosensitive ion protein Piezoelectric pickups for guitars and other...
    1 KB (171 words) - 05:21, 31 January 2023
  • Thumbnail for Hereditary stomatocytosis
    Hereditary xerocytosis is characterized by autosomal dominant mutations in PIEZO1, which encodes a cation channel whose mechanosensitive properties enable...
    12 KB (1,229 words) - 22:12, 20 March 2024
  • lymphatic dysplasia of Fotiou or PIEZO1 disease, is an autosomal recessive genetic disease caused by mutations in the PIEZO1 gene. It results in lymphedema...
    2 KB (153 words) - 12:16, 15 February 2024
  • Jones, B.; Spring, F.A.; et al. (2022). "Missense mutations in PIEZO1, encoding the Piezo1 mechanosensor protein, define the Er red blood cell antigens"...
    3 KB (355 words) - 09:06, 12 February 2024
  • Thumbnail for Serotonin
    deficiency, conditional knockout of Piezo1 increased bone formation. Notably, fecal ssRNA was identified as a natural Piezo1 ligand, and ssRNA-stimulated 5-HT...
    127 KB (13,724 words) - 11:37, 24 March 2024
  • Thumbnail for Chilean rose tarantula
    eye". NBC News. Jan 1, 2010. Retrieved 3 January 2010. "Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular...
    12 KB (1,407 words) - 18:11, 5 January 2024
  • Thumbnail for Jedi2
    compound which acts as an agonist for the mechanosensitive ion channel PIEZO1, and is used in research into the function of touch perception. Yoda1 and...
    2 KB (136 words) - 11:10, 31 October 2023
  • Thumbnail for Baroreflex
    Baroreceptor mechanosensitivity is hypothesised to be linked to the expression of PIEZO1 and PIEZO2 on neurons in the petrosal and nodose ganglia. Baroreceptor action...
    13 KB (1,562 words) - 02:34, 2 January 2024
  • Thumbnail for PIEZO2
    Marden-Walker syndrome and Arthrogryposis (Distal Arthrogryposis Type 5). PIEZO1 GRCh38: Ensembl release 89: ENSG00000154864 – Ensembl, May 2017 GRCm38:...
    9 KB (1,034 words) - 19:53, 8 April 2024
  • Thumbnail for Odontoblast
    controversial It has been shown that odontoblast-neuron signal communication via Piezo1/TRPA1 channels and pannexin-1 in odontoblasts and P2X3 receptors in A-delta...
    10 KB (1,319 words) - 16:19, 3 December 2023
  • Thumbnail for University of California, San Francisco
    Patapoutian, Nobel Prize laureate known for his work in characterizing the PIEZO1, PIEZO2, and TRPM8 receptors William W. Parmley – Former Editor of the Journal...
    90 KB (9,601 words) - 13:49, 19 April 2024
  • Thumbnail for Wolfgang Bernhard Liedtke
    Frederick; Guilak, Farshid; Liedtke, Wolfgang B. (2014-11-25). "Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular...
    22 KB (2,221 words) - 13:34, 22 March 2024
  • Q9HB75 12122 PIERCE1 HGNC:28435 Q5BN46 12123 PIERCE2 HGNC:44654 H3BRN8 12124 PIEZO1 HGNC:28993 Q92508 12125 PIEZO2 HGNC:26270 Q9H5I5 12126 PIF1 HGNC:26220 Q9H611...
    282 KB (17 words) - 22:06, 12 April 2024
  • Thumbnail for Jedi1
    compound which acts as an agonist for the mechanosensitive ion channel PIEZO1, and is used in research into the function of touch perception. Yoda1 and...
    2 KB (145 words) - 11:53, 31 October 2023
  • Thumbnail for Cell extrusion
    by crowding dependent activation of the stretch-activated cation channel Piezo1. Extrusion triggered by replicative stress or by cell competition requires...
    12 KB (1,338 words) - 08:57, 19 March 2024
  • domain channels and the recently cloned cation selective PIEZO family (PIEZO1 and PIEZO2). MSCs can be classified based on the type of ion to which they...
    66 KB (7,817 words) - 13:11, 17 January 2024
  • 2017). "Mechanical stretch triggers rapid epithelial cell division through Piezo1". Nature. 543 (7643): 118–121. doi:10.1038/nature21407. ISSN 1476-4687....
    8 KB (940 words) - 03:22, 3 December 2023
  • Thumbnail for Dipyaman Ganguly
    Ganguly Lab recently discovered a novel regulatory module involving the Piezo1 mechanosensors in human T cells, driven by mechanical cues. They also provided...
    17 KB (1,502 words) - 18:26, 23 April 2024
  • Schmidt M., Earley T.J., Ranade S., Petrus M.J., Dubin A.E., Patapoutian A. Piezo1 and Piezo2 are essential components of distinct mechanically activated cation...
    11 KB (1,109 words) - 20:12, 23 November 2022
  • Thumbnail for GsMTx-4
    targets mechanosensitive channels from the Piezo and TRP families, such as Piezo1 and TRPC6 which are generally bilayer tension-sensitive. This corresponds...
    14 KB (1,193 words) - 08:34, 26 October 2023
  • magnetic field was employed to activate the mechanosensitive cation channel Piezo1. Results of this study show that remote, in vivo manipulation of behavior...
    9 KB (1,024 words) - 00:54, 19 February 2024
  • hereditary stomatocytosis, pseudohyperkalemia, and perinatal edema; 603528; PIEZO1 Dejerine–Sottas disease; 145900; PMP22 Dejerine–Sottas neuropathy; 145900;...
    234 KB (18,877 words) - 12:36, 2 April 2024