Pembrolizumab, sold under the brand name Keytruda, is a humanized antibody used in cancer immunotherapy that treats melanoma, lung cancer, head and neck...

As adjuvant therapy, mRNA-4157 monotherapy and in combination with pembrolizumab have been investigated in patients with resected solid tumors (melanoma...

Favezelimab/pembrolizumab is a fixed-dose combination of two monoclonal antibodies developed by Merck to treat various cancers. Timmerman, John; Lavie...

checkpoint inhibitors include antibodies such as ipilimumab, nivolumab, and pembrolizumab. Dendritic cell therapy provokes anti-tumor responses by causing dendritic...

immunotherapy drugs blocking LAG3, B7-H3, KIR, OX40, PARP, CD27, and ICOS. Pembrolizumab (Keytruda, formerly MK-3475 and lambrolizumab) was developed by Merck...

system. Atezolizumab is an anti PD-L1 monoclonal antibody. Nivolumab and Pembrolizumab are anti PD-1 monoclonal antibodies. Ipilimumab is a monoclonal antibody...

It is being tested by itself and in a fixed-dose combination with pembrolizumab. Garralda, E.; Sukari, A.; Lakhani, N. J.; Patnaik, A.; Lou, Y.; Im...

liver, and that he had begun treatment with the immunotherapy drug pembrolizumab and was about to start radiation therapy. His healthcare was managed...

treatment options. Pembrolizumab monotherapy is an appealing approach for these patients, with median OS of 30 months with pembrolizumab single agent compared...

drugs or products, each with over $1 billion in revenue: Keytruda (pembrolizumab), a humanized antibody used in cancer immunotherapy that had $14.3 billion...

quality-assured biosimilars Afatinib and gefitinib are alternatives Pembrolizumab is an alternative, including quality-assured biosimilars Enzalutamide...

often costly. For example, one immune check point inhibitor treatment, pembrolizumab, costs $10,000 to US$12,000 for a single dose administered every 3 weeks...

PD-L1, but are sometimes effective in those that do not. Treatment with pembrolizumab, atezolizumab, or combination nivolumab plus ipilimumab are all superior...

2014 and by the US FDA in December 2014 to treat metastatic melanoma. Pembrolizumab (Keytruda, MK-3475, Merck), which also targets PD-1 receptors, was approved...

repair benefit from treatment with the immune checkpoint inhibitor drug pembrolizumab and PARP inhibitors, namely olaparib, rucaparib, or niraparib. Bone...

for those whose tumors express PD-L1. And the similar immunotherapy pembrolizumab for those whose tumors have mutations in various DNA repair pathways...

better using immunotherapy, undergoing treatment every three weeks with pembrolizumab. Two Sides of If (2005) "Take No Prisoners"/"Killing Time" (1981) "Whiskey...

cytotoxic component MMAE, and the checkpoint inhibitors, Nivolumab and Pembrolizumab. This has been an important step in the treatment for the few, but still...

cancer, bladder cancer, head and neck cancer, and Hodgkin's lymphoma. Pembrolizumab (brand name Keytruda) is another PD-1 inhibitor that was approved by...

malignancies. Ongoing studies are investigating SD-101 in combination with pembrolizumab (Keytruda), an anti-PD-1 therapy developed by Merck. A Phase 1/2 trial...

relative with MS. Several other monoclonal antibodies like adalimumab, pembrolizumab, nivolumab, and infliximab have been reported to trigger MS as an adverse...

pembrolizumab may have only minimal effects on the rate of death resulting from treatment or the rate at which the cancer advances. Pembrolizumab may...

cancer with mismatch repair deficiency and microsatellite instability. Pembrolizumab is approved for advanced CRC tumours that are MMR deficient and have...

accelerated cutaneous chronic wound healing (24 Mar), phase 3 trialed pembrolizumab addition against recurrent endometrial cancer (27 Mar), a phase 3 trialed...

anti-cancer activities. In 2016, the FDA granted accelerated approval to pembrolizumab for the treatment of people with recurrent or metastatic HNSCC with...

metastatic melanoma include the biologic immunotherapy agents ipilimumab, pembrolizumab, and nivolumab; BRAF inhibitors, such as vemurafenib and dabrafenib;...

Pemetrexed is also recommended in combination with carboplatin and pembrolizumab for the first-line treatment of advanced non-small cell lung cancer...

(e.g. sunitinib), checkpoint inhibitors (e.g. ipilimumab, nivolumab, pembrolizumab, atezolizumab) Contrast agent Gadolininum based contrast agent Other...

Immunotherapy: mechanism of action for Durvalumab, Pembrolizumab, Ipilimumab, Atezolizumab . Adapted from: First line Immunotherapy for Non-Small Cell...

chemoresistant MSI-high tumors, studies conducted on dostarlimab and pembrolizumab display promising results of the tumors reacting well to the therapies...