• Thumbnail for Picrotoxin
    Picrotoxin, also known as cocculin, is a poisonous crystalline plant compound. It was first isolated by the French pharmacist and chemist Pierre François...
    17 KB (1,610 words) - 00:15, 19 May 2024
  • Thumbnail for Pentylenetetrazol
    convulsant potency was strongly correlated to in vitro affinity to the picrotoxin binding site on the GABA-A receptor complex. Many GABA-A ligands, such...
    7 KB (520 words) - 12:43, 14 July 2024
  • Thumbnail for Anamirta cocculus
    Southeast Asian and Indian climbing plant. Its fruit is the source of picrotoxin, a poisonous compound with stimulant properties. The plant is large-stemmed...
    7 KB (610 words) - 15:14, 25 March 2023
  • Thumbnail for Clomethiazole
    Clomethiazole acts as a positive allosteric modulator at the barbiturate/picrotoxin site of the GABAA receptor. It works to enhance the action of the neurotransmitter...
    9 KB (826 words) - 11:08, 25 May 2024
  • Thumbnail for U-93631
    the GABAA receptor. Its binding site seems to be similar to the one of picrotoxin, a potent neurotoxin and convulsant. The binding of U-93631 decreases...
    2 KB (126 words) - 01:21, 7 February 2024
  • Thumbnail for Cocaine
    Convulsants Anatoxin-a Bicuculline DMCM Flurothyl Gabazine Pentetrazol Picrotoxin Strychnine Thujone Eugeroics Adrafinil Armodafinil CRL-40,940 CRL-40,941...
    177 KB (18,917 words) - 11:19, 18 September 2024
  • Thumbnail for Dihydropicrotoxinin
    used in scientific research to study the GABA receptors. Picrotoxin Olsen, R. W (2006). "Picrotoxin-like channel blockers of GABAA receptors". Proceedings...
    1 KB (67 words) - 05:49, 27 August 2021
  • Thumbnail for GABA
    Both inhibition by nerve stimulation and by applied GABA are blocked by picrotoxin. GABA is primarily synthesized from glutamate via the enzyme glutamate...
    51 KB (5,567 words) - 00:03, 9 September 2024
  • Thumbnail for Methamphetamine
    Convulsants Anatoxin-a Bicuculline DMCM Flurothyl Gabazine Pentetrazol Picrotoxin Strychnine Thujone Eugeroics Adrafinil Armodafinil CRL-40,940 CRL-40,941...
    154 KB (15,224 words) - 16:28, 19 September 2024
  • Thumbnail for MDMA
    Convulsants Anatoxin-a Bicuculline DMCM Flurothyl Gabazine Pentetrazol Picrotoxin Strychnine Thujone Eugeroics Adrafinil Armodafinil CRL-40,940 CRL-40,941...
    168 KB (16,136 words) - 05:57, 18 September 2024
  • Thumbnail for Barbiturate
    levomethadone, levorphanol, morphine, oripavine, pethidine, thebaine) Picrotoxin (i.e., picrotin and picrotoxinin) PMBA Riluzole Tropeines (e.g., bemesetron...
    44 KB (4,711 words) - 08:01, 14 September 2024
  • Thumbnail for Potassium permanganate (medical use)
    included as an effort to wash out the stomach in those with strychnine or picrotoxin poisoning. In the United States the FDA requires tablets of the medication...
    13 KB (1,021 words) - 00:57, 23 June 2024
  • Phosphorus trichloride Physostigmine Physostigmine, salicylate (1:1) Picrotoxin Piperidine Pirimifos-ethyl Plutonium Polonium-210 Potassium arsenite Potassium...
    10 KB (825 words) - 19:18, 7 August 2024
  • Thumbnail for Crack cocaine
    Convulsants Anatoxin-a Bicuculline DMCM Flurothyl Gabazine Pentetrazol Picrotoxin Strychnine Thujone Eugeroics Adrafinil Armodafinil CRL-40,940 CRL-40,941...
    35 KB (3,893 words) - 21:34, 19 August 2024
  • Thumbnail for Nitrous oxide
    levomethadone, levorphanol, morphine, oripavine, pethidine, thebaine) Picrotoxin (i.e., picrotin and picrotoxinin) PMBA Riluzole Tropeines (e.g., bemesetron...
    96 KB (10,056 words) - 20:37, 12 September 2024
  • Thumbnail for 2,4-Diaminobutyric acid
    unclear, it has been shown to have anticonvulsant properties against picrotoxin, but over the long term, it could paradoxically cause convulsions. Beart...
    3 KB (225 words) - 17:57, 25 August 2024
  • laudanosine, lindane, oenanthotoxin, pentylenetetrazol, phenylsilatrane, picrotoxin, radequinil, Ro15-4513, sarmazenil, suritozole, terbequinil,...
    8 KB (800 words) - 16:03, 25 May 2024
  • Thumbnail for Nefiracetam
    substances, including: ethanol, chlorodiazepoxide, scopolamine, bicuculline, picrotoxin, and cycloheximide. Unlike other racetams, nefiracetam shows high affinity...
    8 KB (737 words) - 19:13, 31 August 2024
  • Thumbnail for Ichthyothereol
    mice and dogs, producing convulsant effects that are similar to those of picrotoxin. Mukai, Chisato; Miyakoshi, Naoki; Hanaoka, Miyoji (2001). "First Total...
    3 KB (268 words) - 14:31, 3 July 2023
  • Thumbnail for Ginseng
    Convulsants Anatoxin-a Bicuculline DMCM Flurothyl Gabazine Pentetrazol Picrotoxin Strychnine Thujone Eugeroics Adrafinil Armodafinil CRL-40,940 CRL-40,941...
    32 KB (3,103 words) - 21:01, 1 September 2024
  • Thumbnail for Γ-Hydroxybutyric acid
    nilutamide) Oenanthotoxin Pentylenetetrazol (pentetrazol) Phenylsilatrane Picrotoxin (i.e., picrotin, picrotoxinin and dihydropicrotoxinin) Pregnenolone sulfate...
    89 KB (9,446 words) - 22:14, 17 September 2024
  • Thumbnail for Caffeine
    Convulsants Anatoxin-a Bicuculline DMCM Flurothyl Gabazine Pentetrazol Picrotoxin Strychnine Thujone Eugeroics Adrafinil Armodafinil CRL-40,940 CRL-40,941...
    202 KB (20,197 words) - 09:08, 16 September 2024
  • Thumbnail for GABA receptor
    been recognized that, for neurons that are stimulated by bicuculline and picrotoxin, the fast inhibitory response to GABA is due to direct activation of an...
    35 KB (3,892 words) - 05:20, 16 May 2024
  • Thumbnail for Lemon balm
    nilutamide) Oenanthotoxin Pentylenetetrazol (pentetrazol) Phenylsilatrane Picrotoxin (i.e., picrotin, picrotoxinin and dihydropicrotoxinin) Pregnenolone sulfate...
    17 KB (1,695 words) - 10:49, 20 August 2024
  • Thumbnail for Diazepam
    levomethadone, levorphanol, morphine, oripavine, pethidine, thebaine) Picrotoxin (i.e., picrotin and picrotoxinin) PMBA Riluzole Tropeines (e.g., bemesetron...
    102 KB (10,002 words) - 22:27, 3 September 2024
  • Thumbnail for Clonazepam
    levomethadone, levorphanol, morphine, oripavine, pethidine, thebaine) Picrotoxin (i.e., picrotin and picrotoxinin) PMBA Riluzole Tropeines (e.g., bemesetron...
    78 KB (7,585 words) - 19:18, 12 September 2024
  • Thumbnail for Tetramethylenedisulfotetramine
    causing lethal convulsions. Its effect is similar to but stronger than picrotoxin, a GABA-A receptor antagonist widely used in research. As one of the most...
    11 KB (1,065 words) - 02:23, 11 September 2024
  • Selective Brucine Strychnine Tutin Non-selective Bicuculline Caffeine Picrotoxin Pitrazepin Thiocolchicoside Glycine receptor agonist Miyakawa, N; Uchino...
    1 KB (125 words) - 13:14, 15 January 2024
  • Thumbnail for Furosemide
    nilutamide) Oenanthotoxin Pentylenetetrazol (pentetrazol) Phenylsilatrane Picrotoxin (i.e., picrotin, picrotoxinin and dihydropicrotoxinin) Pregnenolone sulfate...
    37 KB (3,619 words) - 01:04, 1 September 2024
  • Thumbnail for Adderall
    Convulsants Anatoxin-a Bicuculline DMCM Flurothyl Gabazine Pentetrazol Picrotoxin Strychnine Thujone Eugeroics Adrafinil Armodafinil CRL-40,940 CRL-40,941...
    57 KB (21,441 words) - 00:10, 17 September 2024