• Thumbnail for Picrotoxin
    Picrotoxin, also known as cocculin, is a poisonous crystalline plant compound. It was first isolated by the French pharmacist and chemist Pierre François...
    17 KB (1,610 words) - 10:18, 11 December 2023
  • Thumbnail for Pentylenetetrazol
    convulsant potency was strongly correlated to in vitro affinity to the picrotoxin binding site on the GABA-A receptor complex. Many GABA-A ligands, such...
    7 KB (520 words) - 05:44, 25 September 2022
  • Thumbnail for U-93631
    the GABAA receptor. Its binding site seems to be similar to the one of picrotoxin, a potent neurotoxin and convulsant. The binding of U-93631 decreases...
    2 KB (126 words) - 01:21, 7 February 2024
  • Thumbnail for Anamirta cocculus
    Southeast Asian and Indian climbing plant. Its fruit is the source of picrotoxin, a poisonous compound with stimulant properties. The plant is large-stemmed...
    7 KB (610 words) - 15:14, 25 March 2023
  • Thumbnail for Cocaine
    Convulsants Anatoxin-a Bicuculline DMCM Flurothyl Gabazine Pentetrazol Picrotoxin Strychnine Thujone Eugeroics Adrafinil Armodafinil CRL-40,940 CRL-40,941...
    162 KB (17,671 words) - 03:29, 28 April 2024
  • Thumbnail for Potassium permanganate (medical use)
    included as an effort to wash out the stomach in those with strychnine or picrotoxin poisoning. In the United States the FDA requires tablets of the medication...
    13 KB (1,034 words) - 18:26, 14 January 2024
  • Thumbnail for Clomethiazole
    Clomethiazole acts as a positive allosteric modulator at the barbiturate/picrotoxin site of the GABAA receptor. It works to enhance the action of the neurotransmitter...
    9 KB (826 words) - 22:58, 24 April 2024
  • Thumbnail for Methamphetamine
    Convulsants Anatoxin-a Bicuculline DMCM Flurothyl Gabazine Pentetrazol Picrotoxin Strychnine Thujone Eugeroics Adrafinil Armodafinil CRL-40,940 CRL-40,941...
    150 KB (14,825 words) - 20:44, 11 March 2024
  • Thumbnail for Tetramethylenedisulfotetramine
    causing lethal convulsions. Its effect is similar to but stronger than picrotoxin, a GABA-A receptor antagonist widely used in research. As one of the most...
    11 KB (1,065 words) - 17:01, 10 January 2024
  • Thumbnail for Nefiracetam
    substances, including: ethanol, chlorodiazepoxide, scopolamine, bicuculline, picrotoxin, and cycloheximide. Unlike other racetams, nefiracetam shows high affinity...
    8 KB (732 words) - 06:00, 7 September 2023
  • Thumbnail for Ginseng
    Convulsants Anatoxin-a Bicuculline DMCM Flurothyl Gabazine Pentetrazol Picrotoxin Strychnine Thujone Eugeroics Adrafinil Armodafinil CRL-40,940 CRL-40,941...
    32 KB (3,104 words) - 16:55, 25 April 2024
  • Thumbnail for MDMA
    Convulsants Anatoxin-a Bicuculline DMCM Flurothyl Gabazine Pentetrazol Picrotoxin Strychnine Thujone Eugeroics Adrafinil Armodafinil CRL-40,940 CRL-40,941...
    165 KB (15,751 words) - 09:43, 28 April 2024
  • Thumbnail for Penicillin
    nilutamide) Oenanthotoxin Pentylenetetrazol (pentetrazol) Phenylsilatrane Picrotoxin (i.e., picrotin, picrotoxinin and dihydropicrotoxinin) Pregnenolone sulfate...
    97 KB (10,473 words) - 13:40, 15 April 2024
  • Thumbnail for Caffeine
    Convulsants Anatoxin-a Bicuculline DMCM Flurothyl Gabazine Pentetrazol Picrotoxin Strychnine Thujone Eugeroics Adrafinil Armodafinil CRL-40,940 CRL-40,941...
    197 KB (19,766 words) - 21:40, 28 April 2024
  • Thumbnail for Γ-Aminobutyric acid
    Both inhibition by nerve stimulation and by applied GABA are blocked by picrotoxin. GABA is primarily synthesized from glutamate via the enzyme glutamate...
    51 KB (5,563 words) - 23:57, 21 March 2024
  • Thumbnail for Zygacine
    atropine to the patient. For animals, treatment consists of atropine, picrotoxin and activated charcoal. Scientists first attempted to determine the toxic...
    12 KB (1,280 words) - 06:10, 14 April 2024
  • Thumbnail for Analeptic
    neurotransmitter glycine. Strychnine is subcategorized as a convulsant along with picrotoxin and bicuculline, though these convulsants inhibit GABA receptors instead...
    14 KB (1,656 words) - 12:52, 24 January 2024
  • Thumbnail for Gamma-Hydroxybutyric acid
    nilutamide) Oenanthotoxin Pentylenetetrazol (pentetrazol) Phenylsilatrane Picrotoxin (i.e., picrotin, picrotoxinin and dihydropicrotoxinin) Pregnenolone sulfate...
    80 KB (8,754 words) - 18:02, 9 April 2024
  • Thumbnail for Lemon balm
    nilutamide) Oenanthotoxin Pentylenetetrazol (pentetrazol) Phenylsilatrane Picrotoxin (i.e., picrotin, picrotoxinin and dihydropicrotoxinin) Pregnenolone sulfate...
    17 KB (1,632 words) - 16:10, 30 March 2024
  • Thumbnail for Glutamine
    nilutamide) Oenanthotoxin Pentylenetetrazol (pentetrazol) Phenylsilatrane Picrotoxin (i.e., picrotin, picrotoxinin and dihydropicrotoxinin) Pregnenolone sulfate...
    27 KB (2,443 words) - 08:45, 27 April 2024
  • Thumbnail for Furosemide
    nilutamide) Oenanthotoxin Pentylenetetrazol (pentetrazol) Phenylsilatrane Picrotoxin (i.e., picrotin, picrotoxinin and dihydropicrotoxinin) Pregnenolone sulfate...
    37 KB (3,648 words) - 20:31, 1 March 2024
  • Thumbnail for Nitrous oxide
    levomethadone, levorphanol, morphine, oripavine, pethidine, thebaine) Picrotoxin (i.e., picrotin and picrotoxinin) PMBA Riluzole Tropeines (e.g., bemesetron...
    96 KB (10,073 words) - 04:52, 11 April 2024
  • Phosphorus trichloride Physostigmine Physostigmine, salicylate (1:1) Picrotoxin Piperidine Pirimifos-ethyl Plutonium Polonium-210 Potassium arsenite Potassium...
    10 KB (825 words) - 05:28, 10 December 2023
  • Thumbnail for RDX
    nilutamide) Oenanthotoxin Pentylenetetrazol (pentetrazol) Phenylsilatrane Picrotoxin (i.e., picrotin, picrotoxinin and dihydropicrotoxinin) Pregnenolone sulfate...
    57 KB (5,907 words) - 17:23, 6 March 2024
  • Thumbnail for Dihydropicrotoxinin
    used in scientific research to study the GABA receptors. Picrotoxin Olsen, R. W (2006). "Picrotoxin-like channel blockers of GABAA receptors". Proceedings...
    1 KB (67 words) - 05:49, 27 August 2021
  • Thumbnail for GABAA receptor
    alcohol (ethanol), inhaled anaesthetics, kavalactones, cicutoxin, and picrotoxin, among others. Much like the GABAA receptor, the GABAB receptor is an...
    54 KB (5,992 words) - 15:58, 28 March 2024
  • Thumbnail for GABA receptor
    been recognized that, for neurons that are stimulated by bicuculline and picrotoxin, the fast inhibitory response to GABA is due to direct activation of an...
    35 KB (3,884 words) - 16:49, 26 April 2024
  • Selective Brucine Strychnine Tutin Non-selective Bicuculline Caffeine Picrotoxin Pitrazepin Thiocolchicoside Glycine receptor agonist Miyakawa, N; Uchino...
    1 KB (125 words) - 13:14, 15 January 2024
  • Thumbnail for Bicuculline
    by IUPHAR as a major criterion in the definition of GABAA receptors  Picrotoxin Hydrastine (very similar in structure) Johnston, Graham AR (2013). "Advantages...
    5 KB (316 words) - 20:39, 11 April 2024
  • G-protein coupled receptors Palytoxin, an extremely poisonous vasoconstrictor Picrotoxin, a poisonous crystalline plant alkaloid Pumiliotoxin, found in dart frogs...
    2 KB (253 words) - 15:47, 14 May 2023