• Thumbnail for Plasminogen activator inhibitor-1
    Plasminogen activator inhibitor-1 (PAI-1) also known as endothelial plasminogen activator inhibitor (serpin E1) is a protein that in humans is encoded...
    13 KB (1,603 words) - 02:15, 10 March 2024
  • Thumbnail for Plasminogen activator
    The main inhibitor of tissue plasminogen activator and urokinase is plasminogen activator inhibitor-1 (PAI-1). Plasminogen activator inhibitor-1 is a serine...
    9 KB (1,083 words) - 14:08, 27 January 2024
  • Thumbnail for Plasminogen activator inhibitor-2
    Plasminogen activator inhibitor-2 (placental PAI, SerpinB2, PAI-2), a serine protease inhibitor of the serpin superfamily, is a coagulation factor that...
    23 KB (2,905 words) - 20:12, 3 December 2023
  • Thumbnail for Tissue-type plasminogen activator
    1992). "Complexes of tissue-type plasminogen activator and its serpin inhibitor plasminogen-activator inhibitor type 1 are internalized by means of the...
    28 KB (3,090 words) - 00:55, 10 March 2024
  • Thumbnail for Urokinase
    urokinase are the serpins plasminogen activator inhibitor-1 (PAI-1) and plasminogen activator inhibitor-2 (PAI-2), which inhibit the protease activity irreversibly...
    20 KB (2,290 words) - 08:54, 4 May 2024
  • Thumbnail for Nattokinase
    strong fibrinolytic activity and works by inactivating plasminogen activator inhibitor 1 (PAI-1). Although it should be expected to be digested and inactivated...
    6 KB (620 words) - 11:09, 22 March 2024
  • Thumbnail for Coagulation
    shrinkage of the clot volume. Plasminogen activators, such as tissue plasminogen activator (t-PA), activate plasminogen into plasmin, which promotes lysis of...
    61 KB (5,960 words) - 10:29, 11 May 2024
  • Thumbnail for Protease
    antithrombin (which protects the body from excessive coagulation), plasminogen activator inhibitor-1 (which protects the body from inadequate coagulation by blocking...
    26 KB (2,799 words) - 22:42, 25 April 2024
  • deficiency of alpha-2-antiplasmin (alpha-2-plasmin inhibitor) or plasminogen activator inhibitor type 1 (PAI-1) are very rare. The affected individuals show...
    7 KB (825 words) - 02:30, 14 September 2022
  • themselves inhibited by plasminogen activator inhibitor-1 and plasminogen activator inhibitor-2 (PAI-1 and PAI-2). In contrast, plasminogen further stimulates...
    9 KB (1,045 words) - 02:49, 20 November 2023
  • imaging Plasminogen activator inhibitor-1 (PAI-1), a protein that inhibits fibrinolysis (breakdown of blood clots) Plasminogen activator inhibitor-2 (PAI-2)...
    2 KB (336 words) - 08:16, 14 August 2023
  • Plasminogen activator Pla (EC 3.4.23.48) is an enzyme. This enzyme catalyses the following chemical reaction Converts human Glu-plasminogen to plasmin...
    3 KB (400 words) - 15:28, 26 August 2023
  • interleukin-6 (IL-6) monocyte chemotactic protein-1 (MCP-1) plasminogen activator inhibitor-1 (PAI-1) retinol binding protein 4 (RBP4) tumor necrosis factor...
    4 KB (443 words) - 07:08, 27 April 2024
  • Thumbnail for Plasmin
    Plasmin (redirect from Plasminogen)
    plasminogen activator. Urokinase plasminogen activator receptor (uPAR) is a cofactor for plasminogen activation by urokinase plasminogen activator. The conversion...
    15 KB (1,821 words) - 02:15, 10 March 2024
  • Thumbnail for Vitronectin
    to plasminogen activator inhibitor-1 (PAI-1), and stabilizes it. Thus vitronectin serves to regulate proteolysis initiated by plasminogen activation. In...
    9 KB (1,057 words) - 10:46, 24 December 2023
  • Thumbnail for Livedo reticularis
    complex antibody Livedo vasculopathy associated with plasminogen activator inhibitor-1 promoter homozygosity and prothrombin G20210A heterozygosity...
    25 KB (2,547 words) - 05:54, 8 March 2024
  • Thumbnail for Alteplase
    Activase among others, is a biosynthetic form of human tissue-type plasminogen activator (t-PA). It is a thrombolytic medication used to treat acute ischemic...
    26 KB (2,334 words) - 20:11, 26 January 2024
  • Thumbnail for Serpin
    "Human plasminogen activator inhibitor-1 (PAI-1) deficiency: characterization of a large kindred with a null mutation in the PAI-1 gene". Blood. 90 (1): 204–208...
    136 KB (14,251 words) - 15:12, 4 May 2024
  • Thumbnail for TFE3
    "Both Max and TFE3 cooperate with Smad proteins to bind the plasminogen activator inhibitor-1 promoter, but they have opposite effects on transcriptional...
    11 KB (1,378 words) - 14:21, 5 January 2024
  • Thumbnail for Antithrombin
    Antithrombin (category Genes on human chromosome 1)
    to that of the physiologically latent conformation of plasminogen activator inhibitor-1 (PAI-1). For this reason the conformation of antithrombin in which...
    45 KB (5,331 words) - 23:48, 9 March 2024
  • Thumbnail for Disseminated intravascular coagulation
    TF and plasminogen activator inhibitor-1 (PAI-1), which prevents fibrinolysis. Excess circulating thrombin results from the excess activation of the coagulation...
    23 KB (2,402 words) - 15:31, 15 January 2024
  • Thumbnail for Acute-phase protein
    Eerenberg AJ, et al. (December 1993). "Alpha-2-macroglobulin functions as an inhibitor of fibrinolytic, clotting, and neutrophilic proteinases in sepsis: studies...
    11 KB (1,096 words) - 14:00, 24 December 2023
  • Thumbnail for Urokinase receptor
    The Urokinase receptor, also known as urokinase plasminogen activator surface receptor (uPAR) or CD87 (Cluster of Differentiation 87), is a protein encoded...
    10 KB (1,151 words) - 09:59, 3 December 2023
  • which are deficient for plasminogen activator inhibitor-1 (PAI-1). PAI-1 inhibits plasminogen activators and thus plasmin activation; therefore it could be...
    50 KB (5,423 words) - 11:11, 28 March 2024
  • Thumbnail for Angiotensin
    Angiotensin (category Genes on human chromosome 1)
    Ursi M, Cerullo G (August 1999). "Angiotensin IV stimulates plasminogen activator inhibitor-1 expression in proximal tubular epithelial cells". Kidney International...
    28 KB (3,127 words) - 04:35, 2 May 2024
  • Thumbnail for SERBP1
    SERBP1 (category Genes on human chromosome 1)
    Plasminogen activator inhibitor 1 RNA-binding protein (serbp1) is a protein that in humans is encoded by the SERBP1 gene. SERBP1 has been shown to interact...
    8 KB (1,034 words) - 20:03, 8 April 2022
  • Thumbnail for TM5441
    is a drug which acts as an inhibitor of the serpin protein plasminogen activator inhibitor-1 (PAI-1). By inhibiting PAI-1, it increases activity of the...
    4 KB (265 words) - 14:37, 9 January 2024
  • Thumbnail for Tiplasinin
    an inhibitor of the serpin protein plasminogen activator inhibitor-1 (PAI-1), thereby increasing activity of the enzymes tissue plasminogen activator and...
    3 KB (316 words) - 19:12, 12 August 2023
  • Thumbnail for Adipose tissue
    Adipose derived hormones include: Adiponectin Resistin Plasminogen activator inhibitor-1 (PAI-1) TNFα IL-6 Leptin Estradiol (E2) Adipose tissues also secrete...
    73 KB (8,489 words) - 02:45, 11 May 2024
  • pulmonary arterial hypertension phenylalanine hydroxylase PAI-1 plasminogen activator inhibitor-1 PAL posterior axillary line PALS Pediatric advanced life support...
    15 KB (66 words) - 13:49, 20 November 2023