• Platelet-activating factor, also known as PAF, PAF-acether or AGEPC (acetyl-glyceryl-ether-phosphorylcholine), is a potent phospholipid activator and...
    16 KB (1,930 words) - 01:51, 11 December 2023
  • Thumbnail for Platelet-activating factor receptor
    The platelet-activating factor receptor (PAF-R) is a G-protein coupled receptor which binds platelet-activating factor. It is encoded in the human by the...
    9 KB (1,097 words) - 22:30, 27 March 2024
  • Thumbnail for Coagulation
    vessel wall). Activation of platelets and platelet plug formation: Platelet activation: Platelet activators, such as platelet activating factor and thromboxane...
    61 KB (5,960 words) - 15:41, 29 April 2024
  • Thumbnail for Platelet-derived growth factor
    Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In particular, PDGF plays a significant...
    24 KB (2,877 words) - 21:19, 6 April 2024
  • Thumbnail for Platelet factor 4
    Platelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4) . This...
    14 KB (1,637 words) - 02:07, 3 December 2023
  • Thumbnail for Lipoprotein-associated phospholipase A2
    Lipoprotein-associated phospholipase A2 (Lp-PLA2) also known as platelet-activating factor acetylhydrolase (PAF-AH) is a phospholipase A2 enzyme that in...
    12 KB (1,378 words) - 05:49, 12 January 2024
  • In enzymology, a platelet-activating factor acetyltransferase (EC 2.3.1.149) is an enzyme that catalyzes the chemical reaction 1-alkyl-2-acetyl-sn-gly...
    2 KB (199 words) - 15:29, 26 August 2023
  • Thumbnail for Rupatadine
    Rupatadine is a second generation antihistamine and platelet-activating factor antagonist used to treat allergies. It was discovered and developed by Uriach [es]...
    9 KB (632 words) - 05:21, 7 April 2024
  • Thumbnail for Lipid signaling
    primarily by activation of ceramidase by growth-inducing proteins such as platelet-derived growth factor and insulin-like growth factor, is consistent...
    55 KB (5,635 words) - 16:43, 24 March 2024
  • Thumbnail for Platelet
    with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot. Platelets have no cell nucleus;...
    70 KB (8,489 words) - 17:12, 12 April 2024
  • Thumbnail for PAFAH1B1
    Platelet-activating factor acetylhydrolase IB subunit alpha is an enzyme that in humans is encoded by the PAFAH1B1 gene. The protein is often referred...
    13 KB (1,514 words) - 02:13, 8 April 2024
  • as platelet-activating factor. There are multiple enzymes with this function: Lipoprotein-associated phospholipase A2 Platelet-activating factor acetylhydrolase...
    2 KB (217 words) - 12:22, 26 August 2023
  • Thumbnail for PAFAH1B2
    Platelet-activating factor acetylhydrolase IB subunit beta is an enzyme that in humans is encoded by the PAFAH1B2 gene. PAFAH1B2 has been shown to interact...
    6 KB (727 words) - 06:40, 7 January 2024
  • In 1979, he published a well-known paper on the structure of platelet-activating factor and its relationship with histamine. He was head of allergy and...
    29 KB (3,101 words) - 20:59, 17 April 2024
  • Thumbnail for Ether lipid
    (dialkenylphospholipids) also exist. The prototypical plasmalogen is platelet-activating factor. The formation of the ether bond in mammals requires two enzymes...
    13 KB (1,392 words) - 19:36, 23 February 2024
  • Thumbnail for PAFAH1B3
    Platelet-activating factor acetylhydrolase IB subunit gamma is an enzyme that in humans is encoded by the PAFAH1B3 gene. PAFAH1B3 has been shown to interact...
    6 KB (730 words) - 07:59, 18 August 2023
  • (February 2006). "Platelet-activating factor acetylhydrolase activity affects sperm motility and serves as a decapacitation factor". Fertility and Sterility...
    7 KB (869 words) - 07:44, 13 February 2023
  • Thumbnail for Von Willebrand factor
    Von Willebrand factor (VWF) (German: [fɔn ˈvɪləbʁant]) is a blood glycoprotein that promotes hemostasis, specifically, platelet adhesion. It is deficient...
    17 KB (2,069 words) - 05:08, 4 January 2024
  • Thumbnail for Eosinophilia
    cytokines, chemokines, growth factors, lipid mediators (e.g. leukotrienes, prostaglandins, platelet activating factor), and toxic proteins (e.g. metalloproteinases...
    50 KB (5,494 words) - 23:11, 25 April 2024
  • Thumbnail for PAFAH2
    substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both...
    5 KB (583 words) - 19:49, 8 April 2022
  • Thumbnail for Israpafant
    (Y-24180) is a drug which acts as a selective antagonist for the platelet-activating factor receptor, and was originally developed for the treatment of asthma...
    5 KB (479 words) - 13:27, 19 December 2023
  • Thumbnail for Fc receptor
    proteases. Activated mast cells also synthesize and secrete lipid-derived mediators (such as prostaglandins, leukotrienes, and platelet-activating factor) and...
    42 KB (4,735 words) - 03:31, 26 March 2024
  • Thumbnail for Apafant
    a potent and selective inhibitor of the phospholipid mediator platelet-activating factor (PAF). It was developed by structural modification of the...
    3 KB (258 words) - 23:43, 23 August 2023
  • Thumbnail for Platelet-derived growth factor receptor
    Platelet-derived growth factor receptors (PDGF-R) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family...
    13 KB (1,563 words) - 09:00, 13 March 2024
  • Thumbnail for B-cell activating factor
    danger activating thrifty genes in order to store fat and to avoid starvation. BAFF shares many activities with PAF (Platelet Activating Factor) and they...
    25 KB (3,095 words) - 14:05, 12 March 2024
  • Thumbnail for Hexadecane
    and hydrogels, and for positron emission tomography. Hexadecyl platelet-activating factor has profound effects on the lung, and hexadecyl glyceryl ether...
    8 KB (562 words) - 17:41, 5 March 2024
  • neurotrophic factor (BDNF) Nerve growth factor (NGF) Neurotrophin-3 (NT-3) Neurotrophin-4 (NT-4) Placental growth factor (PGF) Platelet-derived growth factor (PDGF)...
    10 KB (1,131 words) - 19:14, 31 March 2024
  • Thumbnail for Vasodilation
    causing degranulation. Granules in these cells contain histamine, platelet-activating factor, and other compounds causing clinical manifestation of anaphylaxis-...
    45 KB (4,136 words) - 17:42, 24 April 2024
  • extension of PortableApps files Paroxysmal atrial fibrillation Platelet-activating factor Population attributable fraction (epidemiology) Pure autonomic...
    2 KB (202 words) - 05:41, 5 December 2023
  • Thumbnail for Nicolas Bazan
    transmission by platelet-activating factor. Neuron 9:1211-1216, 1992 Kato K, Clark GD, Bazan NG, Zorumski CF: Platelet activating factor as a potential...
    31 KB (4,361 words) - 20:35, 12 February 2024