• Podocin is a protein component of the filtration slits of podocytes. Glomerular capillary endothelial cells, the glomerular basement membrane and the...
    3 KB (317 words) - 18:57, 31 December 2023
  • Thumbnail for Podocyte
    correct function of the slit diaphragm include nephrin, NEPH1, NEPH2, podocin, CD2AP. and FAT1. Small molecules such as water, glucose, and ionic salts...
    17 KB (1,781 words) - 08:50, 19 March 2024
  • Thumbnail for Focal segmental glomerulosclerosis
    contributes to the filtration barrier; NPHS2, which encodes the protein podocin found in podocytes; and INF2, which encodes the actin-binding protein formin...
    20 KB (2,265 words) - 08:29, 26 April 2024
  • Thumbnail for Kidney
    proteins are expressed in the different compartments of the kidney with podocin and nephrin expressed in glomeruli, Solute carrier family protein SLC22A8...
    61 KB (6,896 words) - 17:09, 20 April 2024
  • Thumbnail for Nephrin
    Saleem MA, Faul C, Kriz W, Shaw AS, Holzman LB, Mundel P (Dec 2001). "Podocin, a raft-associated component of the glomerular slit diaphragm, interacts...
    11 KB (1,352 words) - 07:01, 2 May 2023
  • Thumbnail for Glomerulus (kidney)
    spanned by slit diaphragms consisting of a mat of proteins, including podocin and nephrin. In addition, foot processes have a negatively charged coat...
    17 KB (1,802 words) - 18:09, 14 November 2023
  • Thumbnail for NPHS2
    Podocin is a protein that in humans is encoded by the NPHS2 gene. NPHS2 has been shown to interact with Nephrin and CD2AP. Focal segmental glomerulosclerosis...
    8 KB (1,036 words) - 21:47, 27 March 2024
  • accounting for 40-80% of cases. NPHS2: This gene encodes for the protein podocin. Patients with this genetic mutation develop nephrotic syndrome in the...
    13 KB (1,401 words) - 17:52, 2 September 2023
  • Thumbnail for NOX2
    and contributes to their activation by diacylglycerol: essential role of podocin in formation of this complex". American Journal of Physiology. Cell Physiology...
    20 KB (2,434 words) - 00:26, 3 December 2023
  • Thumbnail for CD2AP
    Saleem MA, Faul C, Kriz W, Shaw AS, Holzman LB, Mundel P (Dec 2001). "Podocin, a raft-associated component of the glomerular slit diaphragm, interacts...
    11 KB (1,288 words) - 02:16, 24 December 2023
  • Thumbnail for Galloway–Mowat syndrome
    mutations in podocyte proteins, such as nephrin, alpha-actinin 4, and podocin, are associated with proteinuria and nephrotic syndrome. There is reduced...
    7 KB (768 words) - 18:15, 25 March 2024
  • Thumbnail for LMX1B
    Harendza S, Stahl RA, Schneider A (2009). "The transcriptional regulation of podocin (NPHS2) by Lmx1b and a promoter single nucleotide polymorphism". Cell....
    8 KB (1,074 words) - 19:29, 2 December 2023
  • Thumbnail for KIRREL
    cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2; MIM 604766). NEPH1 is expressed in filtration slits of kidney podocytes...
    6 KB (674 words) - 21:09, 27 March 2024
  • Thumbnail for SYNPO
    (Apr 2007). "Glomerular expression of nephrin and synaptopodin, but not podocin, is decreased in kidney sections from women with preeclampsia". Nephrology...
    8 KB (1,051 words) - 09:14, 17 November 2023
  • Kerjaschki, D., Thiele, C., Walz, G., Chalfie, M., and Benzing, T. 2006. Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels...
    9 KB (856 words) - 07:27, 7 November 2023
  • Thumbnail for PDZK1
    Quack I, Pavenstädt H, Walz G (2003). "NEPH1 defines a novel family of podocin interacting proteins". FASEB J. 17 (1): 115–7. doi:10.1096/fj.02-0242fje...
    10 KB (1,206 words) - 22:12, 27 March 2024
  • Thumbnail for KIRREL3
    Quack I, Pavenstädt H, Walz G (Jan 2003). "NEPH1 defines a novel family of podocin interacting proteins". FASEB Journal. 17 (1): 115–7. doi:10.1096/fj.02-0242fje...
    6 KB (827 words) - 09:13, 29 March 2024
  • spontaneously differentiate into cells expressing markers of podocytes (podocin; ~31%), mesangial cells (megsin; ~13%), and endothelial cells (CD31; ~41%)...
    77 KB (8,811 words) - 16:03, 7 April 2024