• Polyadenylation is the addition of a poly(A) tail to an RNA transcript, typically a messenger RNA (mRNA). The poly(A) tail consists of multiple adenosine...
    57 KB (7,095 words) - 12:54, 22 February 2024
  • Thumbnail for Mature messenger RNA
    of a mature mRNA molecule occurs in 3 steps: Capping of the 5' end Polyadenylation of the 3' end RNA Splicing of the introns During capping, a 7-methylguanosine...
    6 KB (596 words) - 00:20, 15 February 2023
  • Cleavage and polyadenylation specificity factor (CPSF) is involved in the cleavage of the 3' signaling region from a newly synthesized pre-messenger RNA...
    15 KB (1,894 words) - 16:46, 28 November 2023
  • Thumbnail for SV40
    SV40 is an abbreviation for simian vacuolating virus 40 or simian virus 40, a polyomavirus that is found in both monkeys and humans. Like other polyomaviruses...
    19 KB (2,241 words) - 16:21, 28 March 2024
  • Thumbnail for Three prime untranslated region
    Regulatory regions within the 3′-untranslated region can influence polyadenylation, translation efficiency, localization, and stability of the mRNA. The...
    20 KB (2,555 words) - 11:24, 22 February 2024
  • Thumbnail for Post-transcriptional modification
    tail. The cleavage and adenylation reactions occur primarily if a polyadenylation signal sequence (5'- AAUAAA-3') is located near the 3' end of the pre-mRNA...
    11 KB (1,438 words) - 13:16, 13 April 2024
  • Thumbnail for Messenger RNA
    early stop codon, which, upon translation, produces a shorter protein. Polyadenylation is the covalent linkage of a polyadenylyl moiety to a messenger RNA...
    49 KB (5,922 words) - 00:21, 9 May 2024
  • Thumbnail for CPEB
    CPEB, or cytoplasmic polyadenylation element binding protein, is a highly conserved RNA-binding protein that promotes the elongation of the polyadenine...
    19 KB (2,234 words) - 18:47, 14 December 2023
  • The cytoplasmic polyadenylation element (CPE) is a sequence element found in the 3' untranslated region of messenger RNA. While several sequence elements...
    9 KB (1,178 words) - 13:13, 22 February 2024
  • Thumbnail for Long terminal repeat
    type 1 provirus, polyadenylation signals present in the 5' long terminal repeat (LTR) are disregarded while the identical polyadenylation signals present...
    11 KB (1,378 words) - 11:06, 3 December 2023
  • Thumbnail for U1A polyadenylation inhibition element (PIE)
    The U1A polyadenylation inhibition element (PIE) is an RNA element which is responsible for the regulation of the length of the polyA tail of the U1A...
    2 KB (175 words) - 17:50, 16 January 2022
  • major role in post-transcriptional control of RNAs, such as: splicing, polyadenylation, mRNA stabilization, mRNA localization and translation. Eukaryotic...
    39 KB (4,589 words) - 13:12, 26 August 2023
  • Thumbnail for Primary transcript
    modified by several processes. These processes include the 5' cap, 3'-polyadenylation, and alternative splicing. In particular, alternative splicing directly...
    23 KB (3,023 words) - 12:36, 22 February 2024
  • Thumbnail for GLD-2
    specific RNAs, forming a poly(A) tail, which is a process known as polyadenylation. For RNA specificity, GLD-2 associates with an RNA-binding protein...
    10 KB (1,396 words) - 10:08, 17 October 2022
  • Thumbnail for Gene expression
    decapping. Another modification is 3′ cleavage and polyadenylation. They occur if polyadenylation signal sequence (5′- AAUAAA-3′) is present in pre-mRNA...
    81 KB (9,242 words) - 18:03, 29 April 2024
  • Thumbnail for Protein biosynthesis
    process of post-transcriptionally modifying pre-mRNA through capping, polyadenylation and splicing to produce a mature mRNA molecule ready for export from...
    40 KB (4,342 words) - 18:58, 2 April 2024
  • Thumbnail for Transcription (biology)
    template-independent addition of adenines at its new 3' end, in a process called polyadenylation. Beyond termination by a terminator sequences (which is a part of a...
    58 KB (6,780 words) - 13:42, 20 April 2024
  • Thumbnail for Alternative splicing
    viral proteins. In addition, the primary transcript contained multiple polyadenylation sites, giving different 3' ends for the processed mRNAs. In 1981, the...
    63 KB (7,867 words) - 18:04, 14 May 2024
  • Thumbnail for CPSF3
    Cleavage and polyadenylation specificity factor subunit 3 is a protein that in humans is encoded by the CPSF3 gene. GRCh38: Ensembl release 89: ENSG00000119203...
    6 KB (781 words) - 15:10, 27 March 2024
  • Thumbnail for Gene
    Finally, the ends of gene transcripts are defined by cleavage and polyadenylation (CPA) sites, where newly produced pre-mRNA gets cleaved and a string...
    112 KB (12,720 words) - 01:27, 2 May 2024
  • called transcription vectors. They may lack the sequences necessary for polyadenylation and termination, therefore may not be used for protein production....
    18 KB (2,167 words) - 16:13, 10 May 2024
  • Thumbnail for Translation (biology)
    RNA polymerase Promoter Post-transcription Precursor mRNA (pre-mRNA / hnRNA) 5' capping Splicing Polyadenylation Histone acetylation and deacetylation...
    34 KB (3,974 words) - 16:41, 3 April 2024
  • Thumbnail for Macular degeneration
    ARMS2 gene though destabilization of its mRNA through deletion of the polyadenylation signal. ARMS2 protein may localize to the mitochondria and participate...
    90 KB (9,795 words) - 00:00, 12 May 2024
  • Thumbnail for Cell nucleus
    protein translation. The three main modifications are 5' capping, 3' polyadenylation, and RNA splicing. While in the nucleus, pre-mRNA is associated with...
    87 KB (9,883 words) - 21:56, 26 April 2024
  • Thumbnail for RNA polymerase
    template-independent addition of adenines at its new 3′ end, in a process called polyadenylation. Given that DNA and RNA polymerases both carry out template-dependent...
    41 KB (4,799 words) - 19:34, 17 April 2024
  • behind another vehicle Surveillance, following someone's movements Polyadenylation, adding a poly(-A) tail to a nucleic acid Tail (disambiguation) This...
    471 bytes (98 words) - 00:11, 15 July 2021
  • para-Chlorophenylalanine (fenclonine), a synthetic amino acid Premature cleavage and polyadenylation para-Chlorophenoxyacetate (pCPA), a pesticide Pacific Conservatory...
    583 bytes (89 words) - 17:08, 9 June 2017
  • functional product". Regulatory elements include: Promoter region TATA box Polyadenylation sequences Enhancers These elements work in combination with the open...
    9 KB (1,183 words) - 13:36, 9 February 2023
  • Thumbnail for CPEB1
    Cytoplasmic polyadenylation element-binding protein 1 is a protein that in humans is encoded by the CPEB1 gene. This gene encodes a member of the cytoplasmic...
    4 KB (554 words) - 17:57, 13 January 2024
  • Thumbnail for XIST
    one. It is processed in a similar way to mRNAs, through splicing and polyadenylation. However, it remains untranslated. It has been suggested that this...
    34 KB (4,229 words) - 03:34, 9 March 2024