Polyadenylation is the addition of a poly(A) tail to an RNA transcript, typically a messenger RNA (mRNA). The poly(A) tail consists of multiple adenosine...
57 KB (7,095 words) - 12:54, 22 February 2024
Mature messenger RNA (section Polyadenylation)
of a mature mRNA molecule occurs in 3 steps: Capping of the 5' end Polyadenylation of the 3' end RNA Splicing of the introns During capping, a 7-methylguanosine...
6 KB (596 words) - 00:20, 15 February 2023
Cleavage and polyadenylation specificity factor (CPSF) is involved in the cleavage of the 3' signaling region from a newly synthesized pre-messenger RNA...
15 KB (1,894 words) - 16:46, 28 November 2023
SV40 (redirect from Simian virus 40 late polyadenylation signal (SVLPA))
SV40 is an abbreviation for simian vacuolating virus 40 or simian virus 40, a polyomavirus that is found in both monkeys and humans. Like other polyomaviruses...
19 KB (2,241 words) - 16:21, 28 March 2024
Regulatory regions within the 3′-untranslated region can influence polyadenylation, translation efficiency, localization, and stability of the mRNA. The...
20 KB (2,555 words) - 11:24, 22 February 2024
tail. The cleavage and adenylation reactions occur primarily if a polyadenylation signal sequence (5'- AAUAAA-3') is located near the 3' end of the pre-mRNA...
11 KB (1,438 words) - 13:16, 13 April 2024
Messenger RNA (section Polyadenylation)
early stop codon, which, upon translation, produces a shorter protein. Polyadenylation is the covalent linkage of a polyadenylyl moiety to a messenger RNA...
49 KB (5,922 words) - 00:21, 9 May 2024
CPEB (redirect from Cytoplasmic polyadenylation element binding protein)
CPEB, or cytoplasmic polyadenylation element binding protein, is a highly conserved RNA-binding protein that promotes the elongation of the polyadenine...
19 KB (2,234 words) - 18:47, 14 December 2023
The cytoplasmic polyadenylation element (CPE) is a sequence element found in the 3' untranslated region of messenger RNA. While several sequence elements...
9 KB (1,178 words) - 13:13, 22 February 2024
type 1 provirus, polyadenylation signals present in the 5' long terminal repeat (LTR) are disregarded while the identical polyadenylation signals present...
11 KB (1,378 words) - 11:06, 3 December 2023
The U1A polyadenylation inhibition element (PIE) is an RNA element which is responsible for the regulation of the length of the polyA tail of the U1A...
2 KB (175 words) - 17:50, 16 January 2022
RNA-binding protein (section Polyadenylation)
major role in post-transcriptional control of RNAs, such as: splicing, polyadenylation, mRNA stabilization, mRNA localization and translation. Eukaryotic...
39 KB (4,589 words) - 13:12, 26 August 2023
Primary transcript (section Polyadenylation)
modified by several processes. These processes include the 5' cap, 3'-polyadenylation, and alternative splicing. In particular, alternative splicing directly...
23 KB (3,023 words) - 12:36, 22 February 2024
GLD-2 (section mRNA processing by RNA polyadenylation)
specific RNAs, forming a poly(A) tail, which is a process known as polyadenylation. For RNA specificity, GLD-2 associates with an RNA-binding protein...
10 KB (1,396 words) - 10:08, 17 October 2022
decapping. Another modification is 3′ cleavage and polyadenylation. They occur if polyadenylation signal sequence (5′- AAUAAA-3′) is present in pre-mRNA...
81 KB (9,242 words) - 18:03, 29 April 2024
process of post-transcriptionally modifying pre-mRNA through capping, polyadenylation and splicing to produce a mature mRNA molecule ready for export from...
40 KB (4,342 words) - 18:58, 2 April 2024
template-independent addition of adenines at its new 3' end, in a process called polyadenylation. Beyond termination by a terminator sequences (which is a part of a...
58 KB (6,780 words) - 13:42, 20 April 2024
viral proteins. In addition, the primary transcript contained multiple polyadenylation sites, giving different 3' ends for the processed mRNAs. In 1981, the...
63 KB (7,867 words) - 18:04, 14 May 2024
Cleavage and polyadenylation specificity factor subunit 3 is a protein that in humans is encoded by the CPSF3 gene. GRCh38: Ensembl release 89: ENSG00000119203...
6 KB (781 words) - 15:10, 27 March 2024
Finally, the ends of gene transcripts are defined by cleavage and polyadenylation (CPA) sites, where newly produced pre-mRNA gets cleaved and a string...
112 KB (12,720 words) - 01:27, 2 May 2024
called transcription vectors. They may lack the sequences necessary for polyadenylation and termination, therefore may not be used for protein production....
18 KB (2,167 words) - 16:13, 10 May 2024
RNA polymerase Promoter Post-transcription Precursor mRNA (pre-mRNA / hnRNA) 5' capping Splicing Polyadenylation Histone acetylation and deacetylation...
34 KB (3,974 words) - 16:41, 3 April 2024
ARMS2 gene though destabilization of its mRNA through deletion of the polyadenylation signal. ARMS2 protein may localize to the mitochondria and participate...
90 KB (9,795 words) - 00:00, 12 May 2024
protein translation. The three main modifications are 5' capping, 3' polyadenylation, and RNA splicing. While in the nucleus, pre-mRNA is associated with...
87 KB (9,883 words) - 21:56, 26 April 2024
template-independent addition of adenines at its new 3′ end, in a process called polyadenylation. Given that DNA and RNA polymerases both carry out template-dependent...
41 KB (4,799 words) - 19:34, 17 April 2024
behind another vehicle Surveillance, following someone's movements Polyadenylation, adding a poly(-A) tail to a nucleic acid Tail (disambiguation) This...
471 bytes (98 words) - 00:11, 15 July 2021
para-Chlorophenylalanine (fenclonine), a synthetic amino acid Premature cleavage and polyadenylation para-Chlorophenoxyacetate (pCPA), a pesticide Pacific Conservatory...
583 bytes (89 words) - 17:08, 9 June 2017
functional product". Regulatory elements include: Promoter region TATA box Polyadenylation sequences Enhancers These elements work in combination with the open...
9 KB (1,183 words) - 13:36, 9 February 2023
Cytoplasmic polyadenylation element-binding protein 1 is a protein that in humans is encoded by the CPEB1 gene. This gene encodes a member of the cytoplasmic...
4 KB (554 words) - 17:57, 13 January 2024
one. It is processed in a similar way to mRNAs, through splicing and polyadenylation. However, it remains untranslated. It has been suggested that this...
34 KB (4,229 words) - 03:34, 9 March 2024