• Thumbnail for Post-transcriptional modification
    Transcriptional modification or co-transcriptional modification is a set of biological processes common to most eukaryotic cells by which an RNA primary...
    11 KB (1,438 words) - 13:16, 13 April 2024
  • considered as a product of an interaction between both transcriptional circuits and non-transcriptional elements such as redox oscillations and protein phosphorylation...
    37 KB (4,473 words) - 19:46, 15 April 2024
  • Thumbnail for Post-translational modification
    In molecular biology, post-translational modification (PTM) is the covalent process of changing proteins following protein biosynthesis. PTMs may involve...
    33 KB (3,189 words) - 03:12, 28 March 2024
  • Thumbnail for Protein biosynthesis
    undergoes post-transcriptional modifications in the nucleus to produce a mature mRNA molecule. However, in prokaryotes post-transcriptional modifications are...
    40 KB (4,342 words) - 18:58, 2 April 2024
  • Splicing, or the removal of introns, is a major aspect of post-transcriptional modification, and takes place only in the nucleus of eukaryotes. U7 snRNA...
    17 KB (2,325 words) - 21:13, 1 February 2024
  • features not found in prokaryotes. Most of these relate to post-transcriptional modification of pre-mRNAs to produce mature mRNA ready for translation...
    19 KB (2,328 words) - 01:53, 15 November 2023
  • Thumbnail for RNA
    these modifications in RNA are not fully understood. However, it is notable that, in ribosomal RNA, many of the post-transcriptional modifications occur...
    64 KB (7,522 words) - 07:46, 20 April 2024
  • Thumbnail for Protein isoform
    variable promoter usage, or other post-transcriptional modifications of a single gene; post-translational modifications are generally not considered. (For...
    17 KB (2,013 words) - 01:16, 4 January 2024
  • Thumbnail for Regulation of gene expression
    expression can be modulated, from transcriptional initiation, to RNA processing, and to the post-translational modification of a protein. Often, one gene...
    45 KB (5,230 words) - 17:06, 6 April 2024
  • Thumbnail for Methylprednisolone
    responsible for repressing genes involved in immune cell activation. Post translational modifications (PTMs) also contribute to methylprednisolone signaling and...
    57 KB (5,140 words) - 04:43, 3 April 2024
  • 5'-end of some primary RNA transcripts as part of the set of post-transcriptional modifications which convert raw transcripts into mature RNA products. The...
    253 KB (22,911 words) - 06:11, 21 April 2024
  • Thumbnail for Gene
    Gene (section Transcription)
    can be regulated at any step: from transcriptional initiation, to RNA processing, to post-translational modification of the protein. The regulation of...
    115 KB (12,719 words) - 03:02, 28 March 2024
  • Thumbnail for RNA polymerase II
    Eukaryotic transcription Post-transcriptional modification RNA polymerase I RNA polymerase II holoenzyme RNA polymerase III Transcription (genetics) Kornberg...
    27 KB (3,100 words) - 17:09, 21 April 2024
  • Thumbnail for RNA-Seq
    ability to look at alternative gene spliced transcripts, post-transcriptional modifications, gene fusion, mutations/SNPs and changes in gene expression...
    100 KB (11,026 words) - 10:04, 29 March 2024
  • Thumbnail for Untranslated region
    plays a critical role in translation termination as well as post-transcriptional modification. These often long sequences were once thought to be useless...
    12 KB (1,454 words) - 21:01, 18 January 2024
  • PMID 12409299. Kiss T (2001). "Small nucleolar RNA-guided post-transcriptional modification of cellular RNAs". The EMBO Journal. 20 (14): 3617–22. doi:10...
    20 KB (1,022 words) - 13:20, 22 February 2024
  • Thumbnail for RNA interference
    degraded, post-transcriptional silencing occurs as protein translation is prevented. Transcription can be inhibited via the pre-transcriptional silencing...
    141 KB (15,437 words) - 06:13, 22 April 2024
  • Thumbnail for Cell nucleus
    occurs co-transcriptionally and is the first step in post-transcriptional modification. The 3' poly-adenine tail is only added after transcription is complete...
    87 KB (9,883 words) - 06:50, 22 February 2024
  • polymerase I RNA polymerase III Post-transcriptional modification Transcription (genetics) Eukaryotic transcription Koleske, A.J.; Young, R.A. (1994)...
    37 KB (4,622 words) - 17:05, 6 April 2024
  • organism to regulate gene expression is at the transcriptional level. CREs function to control transcription by acting nearby or within a gene. The most...
    30 KB (3,472 words) - 02:52, 18 February 2024
  • subsequently processed into a mature mRNA by a series of post-transcriptional modifications. metabolism The complete set of chemical reactions which sustain...
    247 KB (21,288 words) - 05:07, 20 April 2024
  • Thumbnail for TEAD1
    Transcriptional enhancer factor TEF-1 also known as TEA domain family member 1 (TEAD1) and transcription factor 13 (TCF-13) is a protein that in humans...
    33 KB (4,077 words) - 09:00, 28 February 2024
  • Thumbnail for U1 spliceosomal RNA
    Splicing, or the removal of introns, is a major aspect of post-transcriptional modification, and takes place only in the nucleus of eukaryotes. In humans...
    11 KB (1,314 words) - 03:20, 25 November 2023
  • motifs have been shown to be predictive of epigenomic modifications, suggesting that transcription factors play a role in regulating the epigenome. In RNA...
    26 KB (2,836 words) - 13:21, 3 December 2023
  • Thumbnail for Gene expression
    modulated (regulated), including the transcription, RNA splicing, translation, and post-translational modification of a protein. Regulation of gene expression...
    81 KB (9,242 words) - 10:26, 20 April 2024
  • the removal of introns from pre-mRNA, a critical aspect of post-transcriptional modification of RNA, occurring only in the nucleus of eukaryotic cells...
    14 KB (1,819 words) - 12:26, 22 February 2024
  • Thumbnail for Polypyrimidine tract
    specialized for carrying out RNA splicing during the process of post-transcriptional modification. The region is rich with pyrimidine nucleotides, especially...
    3 KB (321 words) - 17:00, 1 April 2020
  • Thumbnail for 2'-O-methylation
    PMID 33104789. Kiss T (July 2001). "Small nucleolar RNA-guided post-transcriptional modification of cellular RNAs". The EMBO Journal. 20 (14): 3617–3622. doi:10...
    6 KB (703 words) - 18:10, 19 April 2024
  • Thumbnail for U6 spliceosomal RNA
    Splicing, or the removal of introns, is a major aspect of post-transcriptional modification and takes place only in the nucleus of eukaryotes. The RNA...
    9 KB (1,076 words) - 01:44, 1 December 2023
  • Thumbnail for Rotavirus
    enzyme that catalyses the formation of the 5' cap in the post-transcriptional modification of mRNA. The cap stabilises viral mRNA by protecting it from...
    86 KB (9,955 words) - 11:30, 26 March 2024