• Thumbnail for Prostaglandin EP4 receptor
    Prostaglandin E2 receptor 4 (EP4) is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the PTGER4 gene in humans; it is one of four identified...
    40 KB (4,808 words) - 02:56, 28 March 2024
  • Thumbnail for Prostaglandin E2
    to G coupled protein prostaglandin E2 (PGE2) receptors (EP1, EP2, EP3, and EP4). The activation of these different EP receptors is dependent on the type...
    34 KB (3,565 words) - 18:38, 24 April 2024
  • Prostaglandin receptors or prostanoid receptors represent a sub-class of cell surface membrane receptors that are regarded as the primary receptors for...
    11 KB (879 words) - 12:45, 14 May 2023
  • Thumbnail for Prostaglandin EP3 receptor
    Prostaglandin EP3 receptor (53kDa), also known as EP3, is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the human gene PTGER3; it is...
    38 KB (4,418 words) - 14:47, 27 January 2024
  • Thumbnail for Prostaglandin EP2 receptor
    Prostaglandin E2 receptor 2, also known as EP2, is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the human gene PTGER2: it is one of...
    32 KB (3,685 words) - 02:56, 10 March 2024
  • E2 receptor 2 (EP2) - PTGER2 Prostaglandin E2 receptor 3 (EP3) - PTGER3 Prostaglandin E2 receptor 4 (EP4) - PTGER4 An antagonist of a prostaglandin E2...
    5 KB (509 words) - 01:31, 17 December 2023
  • Thumbnail for Prostaglandin
    X (September 2016). "Prostaglandin E2 (PGE2) promotes proliferation and invasion by enhancing SUMO-1 activity via EP4 receptor in endometrial cancer"...
    24 KB (2,412 words) - 17:04, 12 March 2024
  • Thumbnail for Prostaglandin EP1 receptor
    Prostaglandin receptors Prostanoid receptors Prostaglandin E2 receptor 2 (EP2) Prostaglandin E2 receptor 3 (EP3) Prostaglandin E2 receptor 4 (EP4) Eicosanoid...
    20 KB (2,365 words) - 02:56, 10 March 2024
  • Thumbnail for Prostaglandin F receptor
    Prostaglandin F receptor (FP) is a receptor belonging to the prostaglandin (PG) group of receptors. FP binds to and mediates the biological actions of...
    31 KB (3,533 words) - 02:57, 10 March 2024
  • Thumbnail for Prostaglandin DP2 receptor
    Prostaglandin D2 receptor 2 (DP2 or CRTH2) is a human protein encoded by the PTGDR2 gene and GPR44. DP2 has also been designated as CD294 (cluster of...
    26 KB (3,216 words) - 20:42, 8 March 2024
  • The prostaglandin D2 (PGD2) receptors are G protein-coupled receptors that bind and are activated by prostaglandin D2. Also known as PTGDR or DP receptors...
    8 KB (869 words) - 17:14, 3 December 2023
  • Thumbnail for Prostaglandin F2alpha
    Prostaglandin F2α (PGF2α in prostanoid nomenclature), pharmaceutically termed dinoprost is a naturally occurring prostaglandin used in medicine to induce...
    12 KB (1,134 words) - 18:55, 24 April 2024
  • Thumbnail for Grapiprant
    the prostaglandin EP4 receptor, one out of the four prostaglandin E2 (PGE2) receptor subgroups. The EP4 receptor then mediates the prostaglandin-E2-elicited...
    11 KB (1,033 words) - 23:56, 28 March 2024
  • Prostaglandin analogues are a class of drugs that bind to a prostaglandin receptor. Wider use of prostaglandin analogues is limited by unwanted side effects...
    3 KB (342 words) - 13:42, 11 October 2023
  • Thumbnail for Prostaglandin DP1 receptor
    The prostaglandin D2 receptor 1 (DP1), a G protein-coupled receptor encoded by the PTGDR1 gene (also termed PTGDR), is primarily a receptor for prostaglandin...
    25 KB (3,084 words) - 03:09, 10 March 2024
  • Thumbnail for Prostaglandin D2
    Prostaglandin D2 (or PGD2) is a prostaglandin that binds to the receptor PTGDR (DP1), as well as CRTH2 (DP2). It is a major prostaglandin produced by...
    11 KB (1,090 words) - 00:21, 17 February 2024
  • Thumbnail for Ankylosing spondylitis
    prostaglandin EP4 receptor, one of four receptors for prostaglandin E2. Activation of EP4 promotes bone remodeling and deposition (see prostaglandin EP4...
    56 KB (5,991 words) - 09:28, 7 April 2024
  • Thumbnail for Prostaglandin E1
    Prostaglandin E1 (PGE1) is a naturally occurring prostaglandin and is also used as a medication (alprostadil). In infants with congenital heart defects...
    13 KB (1,116 words) - 05:55, 18 March 2024
  • Thumbnail for Prostacyclin
    Prostacyclin (also called prostaglandin I2 or PGI2) is a prostaglandin member of the eicosanoid family of lipid molecules. It inhibits platelet activation...
    20 KB (1,639 words) - 08:58, 22 December 2023
  • Thumbnail for Iloprost
    Iloprost (category Prostaglandins)
    receptors for prostaglandin E2 viz., prostaglandin EP1 receptor, prostaglandin EP2 receptor, prostaglandin EP3 receptor, and prostaglandin EP4 receptor. Activation...
    10 KB (694 words) - 01:42, 6 May 2024
  • Thumbnail for Prostaglandin G2
    Prostaglandin G2 is an organic peroxide belonging to the family of prostaglandins. The compound has been isolated as a solid, although it is usually used...
    3 KB (143 words) - 18:37, 24 April 2024
  • Thumbnail for Cyclooxygenase
    Cyclooxygenase (COX), officially known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme (specifically, a family of isozymes, EC 1.14.99.1)...
    15 KB (1,672 words) - 11:53, 28 December 2023
  • Thumbnail for Prostaglandin H2
    Prostaglandin H2 (PGH2), or prostaglandin H2 (PGH2), is a type of prostaglandin and a precursor for many other biologically significant molecules. It...
    6 KB (505 words) - 01:38, 1 March 2024
  • Thumbnail for Sulprostone
    responses to PGE2: prostaglandin EP1 receptor, prostaglandin EP2 receptor, prostaglandin EP3 receptor, and prostaglandin EP4 receptor. Sulprosotone binds...
    6 KB (433 words) - 05:50, 6 May 2024
  • Thumbnail for Carprofen
    administered intravenously to horses. A single dose has been shown to reduce prostaglandin E2 production and inflammatory exudate for up to 15 hours, although...
    18 KB (1,662 words) - 13:46, 31 March 2024
  • Thumbnail for Prostacyclin receptor
    Prostacyclin receptor, also termed the prostaglandin I2 receptor or just IP, is a receptor belonging to the prostaglandin (PG) group of receptors. IP binds...
    31 KB (3,763 words) - 02:54, 10 March 2024
  • Thumbnail for Misoprostol
    Misoprostol (category Prostaglandins)
    and stimulates prostaglandin EP2 receptors, prostaglandin EP3 receptor and prostaglandin EP4 receptor but not prostaglandin EP1 receptor and therefore...
    51 KB (4,740 words) - 06:11, 14 February 2024
  • Thumbnail for Thromboxane
    enzyme found in platelets, converts the arachidonic acid derivative prostaglandin H2 to thromboxane. People with asthma tend to have increased thromboxane...
    10 KB (1,144 words) - 16:24, 28 October 2023
  • effect of grapiprant, a prostaglandin EP4 receptor antagonist, which uses allosteric inhibition to prevent PGE2 to bind to its receptor as opposed to generally...
    6 KB (771 words) - 18:37, 24 April 2024
  • Thumbnail for Aspirin
    of Surgeons in London, showed aspirin suppressed the production of prostaglandins and thromboxanes. For this discovery he was awarded the 1982 Nobel Prize...
    153 KB (16,465 words) - 15:13, 21 April 2024