• Thumbnail for Protease
    A protease (also called a peptidase, proteinase, or proteolytic enzyme) is an enzyme that catalyzes proteolysis, breaking down proteins into smaller polypeptides...
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  • Thumbnail for Serine protease
    Serine proteases (or serine endopeptidases) are enzymes that cleave peptide bonds in proteins. Serine serves as the nucleophilic amino acid at the (enzyme's)...
    22 KB (2,331 words) - 22:33, 25 April 2024
  • and COVID-19. These protease inhibitors prevent viral replication by selectively binding to viral proteases (e.g. HIV-1 protease) and blocking proteolytic...
    15 KB (1,168 words) - 04:21, 24 December 2023
  • Thumbnail for Cysteine protease
    Cysteine proteases, also known as thiol proteases, are hydrolase enzymes that degrade proteins. These proteases share a common catalytic mechanism that...
    14 KB (1,278 words) - 22:29, 25 April 2024
  • Protease inhibitor can refer to: Protease inhibitor (pharmacology): a class of medication that inhibits viral protease Protease inhibitor (biology): molecules...
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  • Thumbnail for Catalytic triad
    triads are most commonly found in hydrolase and transferase enzymes (e.g. proteases, amidases, esterases, acylases, lipases and β-lactamases). An acid-base-nucleophile...
    57 KB (5,790 words) - 05:52, 24 February 2024
  • Protease A may refer to one of two enzymes: Streptogrisin A Omptin This disambiguation page lists articles associated with the title Protease A. If an...
    95 bytes (44 words) - 19:59, 29 December 2019
  • Thumbnail for TEV protease
    three proteases: P1 protease (1 cleavage site), helper-component protease (1 cleavage site) and TEV protease (7 cleavage sites). The native TEV protease also...
    15 KB (1,838 words) - 12:13, 26 August 2023
  • Thumbnail for Prion
    Prion (redirect from Protease-resistant PrP)
    in infectious material has a different structure and is resistant to proteases, the enzymes in the body that can normally break down proteins. The normal...
    98 KB (10,631 words) - 18:49, 17 April 2024
  • Thumbnail for 3C-like protease
    3C-like protease (3CLpro) or main protease (Mpro), formally known as C30 endopeptidase or 3-chymotrypsin-like protease, is the main protease found in...
    21 KB (2,048 words) - 12:43, 27 December 2023
  • Thumbnail for Glutamic protease
    sixth catalytic type of protease. Members of this group of protease had been previously assumed to be an aspartate protease, but structural determination...
    8 KB (851 words) - 13:07, 3 December 2023
  • Thumbnail for Proteinase K
    Proteinase K (redirect from Protease K)
    In molecular biology, Proteinase K (EC 3.4.21.64, protease K, endopeptidase K, Tritirachium alkaline proteinase, Tritirachium album serine proteinase,...
    10 KB (1,034 words) - 16:42, 7 November 2023
  • Thumbnail for Variably protease-sensitive prionopathy
    Variably protease-sensitive prionopathy (VPSPr) (formerly known as Protease Sensitive Prionopathy) is a sporadic prion protein disease first described...
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  • Thumbnail for Lon protease family
    In molecular biology, the Lon protease family is a family of enzymes that break peptide bonds in proteins resulting in smaller peptides or amino acids...
    4 KB (397 words) - 12:40, 9 July 2023
  • Thumbnail for Rhomboid protease
    The rhomboid proteases are a family of enzymes that exist in almost all species. They are proteases: they cut the polypeptide chain of other proteins....
    42 KB (4,629 words) - 01:58, 16 December 2023
  • Protease-activated receptors (PAR) are a subfamily of related G protein-coupled receptors that are activated by cleavage of part of their extracellular...
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  • (HIV protease inhibitor) Darunavir (HIV protease inhibitor) Delavirdine (non-nucleoside reverse transcriptase inhibitor) Fosamprenavir (HIV protease inhibitor)...
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  • Thumbnail for Threonine protease
    Threonine proteases are a family of proteolytic enzymes harbouring a threonine (Thr) residue within the active site. The prototype members of this class...
    5 KB (434 words) - 22:58, 25 April 2024
  • Thumbnail for Aspartic protease
    Aspartic proteases (also "aspartyl proteases", "aspartic endopeptidases") are a catalytic type of protease enzymes that use an activated water molecule...
    10 KB (999 words) - 06:14, 23 February 2023
  • Thumbnail for Active site
    produce a favourable interaction. Many enzymes including serine protease, cysteine protease, protein kinase and phosphatase evolved to form transient covalent...
    40 KB (4,839 words) - 23:49, 6 November 2023
  • Thumbnail for HIV-1 protease
    HIV-1 protease or PR is a retroviral aspartyl protease (retropepsin), an enzyme involved with peptide bond hydrolysis in retroviruses, that is essential...
    20 KB (2,197 words) - 00:57, 13 January 2024
  • Thumbnail for Actinidain
    22.14, actinidin, Actinidia anionic protease, proteinase A2 of Actinidia chinensis) is a type of cysteine protease enzyme found in fruits including kiwifruit...
    16 KB (1,922 words) - 15:42, 27 November 2023
  • Protease VII may refer to: Omptin Caspase 1 This disambiguation page lists articles associated with the title Protease VII. If an internal link led you...
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  • Thumbnail for Serpin
    proteins with similar structures that were first identified for their protease inhibition activity and are found in all kingdoms of life. The acronym...
    136 KB (14,251 words) - 02:22, 19 March 2024
  • two classes of acidic proteases: Aspartic proteases - that use a catalytic aspartic acid in their active site Glutamic proteases - that use a catalytic...
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  • Thumbnail for Subtilisin
    Subtilisin (redirect from Protease XXVII)
    is a protease (a protein-digesting enzyme) initially obtained from Bacillus subtilis. Subtilisins belong to subtilases, a group of serine proteases that...
    12 KB (1,202 words) - 16:36, 2 April 2024
  • Thumbnail for Pancreatic enzymes (medication)
    pancrelipase and pancreatin, are commercial mixtures of amylase, lipase, protease and lactase. They are used to treat malabsorption syndrome due to certain...
    16 KB (1,371 words) - 03:56, 29 April 2024
  • Thumbnail for Zingibain
    Zingibain (redirect from Ginger protease)
    Zingibain, zingipain, or ginger protease (EC 3.4.22.67) is a cysteine protease enzyme found in ginger (Zingiber officinale) rhizomes. It catalyses the...
    16 KB (1,872 words) - 00:10, 31 January 2024
  • endopeptidase or Alpha-lytic protease (EC 3.4.21.12, myxobacter alpha-lytic proteinase, alpha-lytic proteinase, alpha-lytic protease, Mycobacterium sorangium...
    4 KB (444 words) - 03:13, 30 March 2024
  • In biology and biochemistry, protease inhibitors, or antiproteases, are molecules that inhibit the function of proteases (enzymes that aid the breakdown...
    19 KB (1,811 words) - 01:19, 29 November 2023