Protein–protein interactions (PPIs) are physical contacts of high specificity established between two or more protein molecules as a result of biochemical...

contributed an understanding of protein folding and structure mediated by hydrophobic interactions. The first protein to be sequenced was insulin, by...

Protein–protein interaction prediction is a field combining bioinformatics and structural biology in an attempt to identify and catalog physical interactions...

chain. Protein complexes are a form of quaternary structure. Proteins in a protein complex are linked by non-covalent protein–protein interactions. These...

native structure of a protein. Tertiary structure of a protein involves a single polypeptide chain; however, additional interactions of folded polypeptide...

of skin penetration. Protein A can inflame lung tissue by binding to tumor necrosis factor 1 (TNFR-1) receptors. This interaction has been shown to play...

non-covalent interactions, such as hydrogen bonding, ionic interactions, Van der Waals forces, and hydrophobic packing. To understand the functions of proteins at...

Protein–protein interaction screening refers to the identification of Protein–protein interaction with high-throughput screening methods such as computer-...

activator like effectors. Structural proteins that bind DNA are well-understood examples of non-specific DNA-protein interactions. Within chromosomes, DNA is held...

Protein biosynthesis (or protein synthesis) is a core biological process, occurring inside cells, balancing the loss of cellular proteins (via degradation...

affects a large portion of proteins. Even if a protein is not phosphorylated itself, its interactions with other proteins may be regulated by phosphorylation...

Motor proteins are a class of molecular motors that can move along the cytoskeleton of cells. They convert chemical energy into mechanical work by the...

to investigate protein–protein interactions which are the physical contacts of high specificity established between two or more protein molecules involving...

G-protein activation. However, the possibility for interaction does allow for G-protein-independent signaling to occur. There are three main G-protein-mediated...

biology research in order to track protein interactions in real time. The first fluorescent tag, green fluorescent protein (GFP), was isolated from Aequorea...

In molecular biology, a protein domain is a region of a protein's polypeptide chain that is self-stabilizing and that folds independently from the rest...

or whole organisms. Protein purification is vital for the specification of the function, structure and interactions of the protein of interest. The purification...

chromosome stability, its interaction with the cellular transcriptome, its interaction with other cytoskeletal or synaptic proteins, its involvement in myelination...

In biochemistry, a protein dimer is a macromolecular complex or multimer formed by two protein monomers, or single proteins, which are usually non-covalently...

Membrane proteins are common proteins that are part of, or interact with, biological membranes. Membrane proteins fall into several broad categories depending...

SNARE proteins – "SNAP REceptors" – are a large protein family consisting of at least 24 members in yeasts, more than 60 members in mammalian cells, and...

Protein–protein interactions can be designed using protein design algorithms because the principles that rule protein stability also rule protein–protein binding...

A protein kinase is a kinase which selectively modifies other proteins by covalently adding phosphates to them (phosphorylation) as opposed to kinases...

website. Biology portal Protein design Protein function prediction Protein–protein interaction prediction Gene prediction Protein structure prediction software...

between a protein and a functional, proteinaceous unit was difficult to elucidate. More recently, people refer to protein–protein interaction when discussing...

precipitate a protein. Addition of a neutral salt, such as ammonium sulfate, compresses the solvation layer and increases protein–protein interactions. As the...

Protein targeting or protein sorting is the biological mechanism by which proteins are transported to their appropriate destinations within or outside...

enhance signaling specificity by preventing unnecessary interactions between signaling proteins, and enhance signaling efficiency by increasing the proximity...

pathway DNA-binding protein STAT Inhibitors Key steps of the JAK-STAT pathway Structure of the amino-terminal protein interaction domain of STAT-4. Vinkemeier...

outwards, allowing dipole–dipole interactions with the solvent, which explains the molecule's solubility. Globular proteins are only marginally stable because...