• Thumbnail for Protein kinase B
    Protein kinase B (PKB), also known as Akt, is the collective name of a set of three serine/threonine-specific protein kinases that play key roles in multiple...
    34 KB (3,754 words) - 20:14, 23 April 2024
  • Thumbnail for Protein kinase A
    In cell biology, protein kinase A (PKA) is a family of serine-threonine kinase whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA...
    27 KB (2,665 words) - 17:03, 6 April 2024
  • Thumbnail for Serine/threonine-specific protein kinase
    A serine/threonine protein kinase (EC 2.7.11.-) is a kinase enzyme, in particular a protein kinase, that phosphorylates the OH group of the amino-acid...
    14 KB (1,202 words) - 14:08, 17 January 2024
  • Thumbnail for AMP-activated protein kinase
    5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular...
    64 KB (7,058 words) - 23:58, 14 February 2024
  • In cell biology, Protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling...
    27 KB (2,650 words) - 21:16, 19 March 2024
  • A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of protein kinase that is specific to the amino acids serine and threonine (i.e., a...
    46 KB (5,501 words) - 14:24, 23 February 2024
  • Mitogen-activated protein kinase kinase (also known as MAP2K, MEK, MAPKK) is a dual-specificity kinase enzyme which phosphorylates mitogen-activated protein kinase (MAPK)...
    3 KB (296 words) - 17:06, 14 September 2023
  • Thumbnail for C-Jun N-terminal kinases
    transcriptional activation domain. They belong to the mitogen-activated protein kinase family, and are responsive to stress stimuli, such as cytokines, ultraviolet...
    14 KB (1,626 words) - 23:36, 8 August 2023
  • p38 mitogen-activated protein kinases are a class of mitogen-activated protein kinases (MAPKs) that are responsive to stress stimuli, such as cytokines...
    14 KB (1,385 words) - 10:32, 28 April 2024
  • biology, extracellular signal-regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinase intracellular signalling molecules that...
    11 KB (1,128 words) - 19:03, 18 September 2023
  • Thumbnail for Rho-associated protein kinase
    Rho-associated protein kinase (ROCK) is a kinase belonging to the AGC (PKA/ PKG/PKC) family of serine-threonine specific protein kinases. It is involved...
    19 KB (2,168 words) - 00:36, 9 November 2023
  • Thumbnail for Cyclin-dependent kinase 1
    Cyclin-dependent kinase 1 also known as CDK1 or cell division cycle protein 2 homolog is a highly conserved protein that functions as a serine/threonine protein kinase...
    24 KB (2,875 words) - 23:48, 3 December 2023
  • Thumbnail for Phosphoinositide-dependent kinase-1
    In the field of biochemistry, PDPK1 refers to the protein 3-phosphoinositide-dependent protein kinase-1, an enzyme which is encoded by the PDPK1 gene in...
    18 KB (2,127 words) - 19:11, 8 April 2024
  • Thumbnail for ATM serine/threonine kinase
    ATM serine/threonine kinase or Ataxia-telangiectasia mutated, symbol ATM, is a serine/threonine protein kinase that is recruited and activated by DNA...
    50 KB (5,639 words) - 20:54, 11 March 2024
  • Thumbnail for Ca2+/calmodulin-dependent protein kinase II
    Ca2+ /calmodulin-dependent protein kinase II (CaM kinase II or CaMKII) is a serine/threonine-specific protein kinase that is regulated by the Ca2+ /calmodulin...
    29 KB (3,458 words) - 16:39, 17 March 2024
  • Thumbnail for Myotonin-protein kinase
    Myotonin-protein kinase (MT-PK) also known as myotonic dystrophy protein kinase (MDPK) or dystrophia myotonica protein kinase (DMPK) is an enzyme that...
    19 KB (2,426 words) - 16:47, 30 March 2024
  • Thumbnail for CGMP-dependent protein kinase
    cGMP-dependent protein kinase or protein kinase G (PKG) is a serine/threonine-specific protein kinase that is activated by cGMP. It phosphorylates a number...
    8 KB (825 words) - 21:37, 20 April 2023
  • Thumbnail for Receptor tyrosine kinase
    unique tyrosine kinase genes identified in the human genome, 58 encode receptor tyrosine kinase proteins. Receptor tyrosine kinases have been shown not...
    28 KB (3,078 words) - 16:24, 2 April 2024
  • Thumbnail for Tyrosine kinase
    switch in many cellular functions. Tyrosine kinases belong to a larger class of enzymes known as protein kinases which also attach phosphates to other amino...
    43 KB (5,251 words) - 14:08, 17 January 2024
  • Thumbnail for Tropomyosin receptor kinase B
    Tropomyosin receptor kinase B (TrkB), also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor,...
    40 KB (4,321 words) - 10:20, 23 March 2024
  • Thumbnail for RAF kinase
    RAF kinases are a family of three serine/threonine-specific protein kinases that are related to retroviral oncogenes. The mouse sarcoma virus 3611 contains...
    5 KB (550 words) - 09:18, 11 June 2022
  • Thumbnail for MTOR
    phosphatidylinositol 3-kinase-related kinase family of protein kinases. mTOR links with other proteins and serves as a core component of two distinct protein complexes...
    120 KB (12,710 words) - 11:01, 11 April 2024
  • Thumbnail for Cyclin-dependent kinase
    Cyclin-dependent kinases (CDKs) are a predominant group of serine/threonine protein kinases involved in the regulation of the cell cycle and its progression...
    35 KB (3,829 words) - 23:39, 22 April 2024
  • Thumbnail for P70-S6 Kinase 1
    Ribosomal protein S6 kinase beta-1 (S6K1), also known as p70S6 kinase (p70S6K, p70-S6K), is an enzyme (specifically, a protein kinase) that in humans...
    17 KB (2,127 words) - 02:01, 8 April 2024
  • Activated Protein (MAP) kinase kinase kinase (MAPKKK, MKKK, M3K, or, MAP3K) is a serine/threonine-specific protein kinase which acts upon MAP kinase kinase. Subsequently...
    11 KB (1,345 words) - 09:11, 2 January 2024
  • The IκB kinase enzyme complex is part of the upstream NF-κB signal transduction cascade. The IκBα (inhibitor of nuclear factor kappa B) protein inactivates...
    14 KB (1,447 words) - 09:31, 22 December 2023
  • Thumbnail for Cyclin-dependent kinase 4
    Cyclin-dependent kinase 4 also known as cell division protein kinase 4 is an enzyme that in humans is encoded by the CDK4 gene. CDK4 is a member of the...
    21 KB (2,367 words) - 17:04, 14 September 2023
  • Thumbnail for Proto-oncogene tyrosine-protein kinase Src
    Proto-oncogene tyrosine-protein kinase Src, also known as proto-oncogene c-Src, or simply c-Src (cellular Src; pronounced "sarc", as it is short for sarcoma)...
    22 KB (2,795 words) - 13:19, 2 May 2024
  • Thumbnail for Bruton's tyrosine kinase
    Bruton's tyrosine kinase (abbreviated Btk or BTK), also known as tyrosine-protein kinase BTK, is a tyrosine kinase that is encoded by the BTK gene in humans...
    22 KB (2,389 words) - 06:43, 22 April 2024
  • Thumbnail for Phosphoinositide 3-kinase
    identification of a previously unknown phosphoinositide kinase associated with the polyoma middle T protein. They observed unique substrate specificity and chromatographic...
    32 KB (3,463 words) - 17:34, 20 November 2023