• Protein targeting or protein sorting is the biological mechanism by which proteins are transported to their appropriate destinations within or outside...
    52 KB (6,394 words) - 03:48, 19 March 2024
  • Thumbnail for Thylakoid
    thylakoid proteins encoded by a plant's nuclear genome need two targeting signals for proper localization: An N-terminal chloroplast targeting peptide (shown...
    37 KB (4,369 words) - 21:49, 8 May 2024
  • with the PROTAC itself being recycled after the target protein is degraded. The protein targeting warhead, E3 ligase, and linker must all be considered...
    14 KB (1,496 words) - 21:45, 24 April 2024
  • which is referred to as uORFs (upstream open reading frames). Protein targeting Target peptide Topogenic sequence Kapp, Katja; Schrempf, Sabrina; Lemberg...
    15 KB (1,741 words) - 18:05, 31 December 2023
  • Thumbnail for MTOR
    mammalian target of rapamycin (mTOR), also referred to as the mechanistic target of rapamycin, and sometimes called FK506-binding protein 12-rapamycin-associated...
    120 KB (12,710 words) - 11:01, 11 April 2024
  • Thumbnail for Chaperone (protein)
    molecular chaperones are proteins that assist the conformational folding or unfolding of large proteins or macromolecular protein complexes. There are a...
    29 KB (3,499 words) - 07:16, 20 February 2024
  • Target proteins are functional biomolecules that are addressed and controlled by biologically active compounds. They are used in the processes of transduction...
    2 KB (205 words) - 05:46, 29 November 2023
  • Targeting may refer to: Gene targeting Protein targeting Behavioral targeting Targeted advertising Target market Geotargeting, in internet marketing Targeting...
    886 bytes (123 words) - 00:54, 23 July 2021
  • Thumbnail for Protein folding
    Protein folding is the physical process by which a protein, after synthesis by a ribosome as a linear chain of amino acids, changes from an unstable random...
    75 KB (8,663 words) - 11:40, 10 May 2024
  • Thumbnail for Protein
    Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions...
    99 KB (11,235 words) - 04:23, 13 May 2024
  • amphipathic helix. Mitochondrial targeting signals can contain additional signals that subsequently target the protein to different regions of the mitochondria...
    11 KB (1,148 words) - 22:28, 2 April 2024
  • Thumbnail for Ubiquitin ligase
    target protein. The E3, which may be a multi-protein complex, is, in general, responsible for targeting ubiquitination to specific substrate proteins...
    24 KB (2,752 words) - 06:16, 4 March 2024
  • Thumbnail for Chloroplast DNA
    unique protein targeting system to avoid having chloroplast proteins being sent to the wrong organelle. Polypeptides, the precursors of proteins, are chains...
    55 KB (5,829 words) - 08:40, 22 February 2024
  • Thumbnail for Pea protein
    Pea protein is a food product and protein supplement derived and extracted from yellow and green split peas, Pisum sativum. It can be used as a dietary...
    19 KB (2,380 words) - 18:13, 26 March 2024
  • Heat shock proteins (HSPs) are a family of proteins produced by cells in response to exposure to stressful conditions. They were first described in relation...
    49 KB (5,525 words) - 05:03, 26 April 2024
  • Thumbnail for Translocase of the outer membrane
    Translocase of the outer membrane (category Protein pages needing a picture)
    contain internal targeting signals, these signals have an indefinable nature and are inconsistent in their pattern. Proteins targeted to the outer membrane...
    9 KB (1,046 words) - 10:48, 17 March 2024
  • Thumbnail for Protein–protein interaction
    Proteinprotein interactions (PPIs) are physical contacts of high specificity established between two or more protein molecules as a result of biochemical...
    74 KB (8,396 words) - 00:09, 26 April 2024
  • Thumbnail for Eukaryotic ribosome
    cell newly synthesized proteins must be targeted to the appropriate location in the cell, which is achieved by protein targeting and translocation systems...
    40 KB (3,977 words) - 01:19, 21 April 2024
  • Thumbnail for SUMO protein
    Ubiquitin-like Modifier) proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their...
    22 KB (2,753 words) - 18:34, 26 March 2024
  • Bulk movement (category Protein targeting)
    bulk flow. [citation needed] Protein targeting Vesicle (biology) COPI COPII Mass flow 1. Rothman J.E. and Weiland F.T. Protein sorting by transport vesicles...
    1 KB (120 words) - 19:58, 3 October 2023
  • protein complex was a valid identification. If a particular protein can only be recovered by targeting one of the known members but not by targeting other...
    30 KB (4,346 words) - 06:33, 21 December 2023
  • of protein targeting in cells. Prediction of protein subcellular localization is an important component of bioinformatics based prediction of protein function...
    13 KB (1,359 words) - 20:51, 4 January 2024
  • universally conserved ribonucleoprotein (protein-RNA complex) that recognizes and targets specific proteins to the endoplasmic reticulum in eukaryotes...
    13 KB (1,203 words) - 22:07, 23 April 2024
  • Thumbnail for Post-translational modification
    covalent process of changing proteins following protein biosynthesis. PTMs may involve enzymes or occur spontaneously. Proteins are created by ribosomes,...
    33 KB (3,189 words) - 03:12, 28 March 2024
  • Thumbnail for Major prion protein
    prion protein (PrP) is encoded in the human body by the PRNP gene also known as CD230 (cluster of differentiation 230). Expression of the protein is most...
    45 KB (5,228 words) - 07:32, 9 March 2024
  • Translocon (redirect from Sec proteins)
    different proteins have been suggested to be responsible for transport from the ER lumen into the cytosol. SecY protein Sec61 Protein targeting Bacterial...
    13 KB (1,614 words) - 08:59, 7 November 2023
  • Thumbnail for Peripheral membrane protein
    membrane. Binding of a protein to a specific lipid occurs via specific membrane-targeting structural domains that occur within the protein and have specific...
    55 KB (4,391 words) - 16:59, 23 March 2024
  • Thumbnail for Hsp90
    Hsp90 (redirect from Heat shock protein 90)
    shock protein 90) is a chaperone protein that assists other proteins to fold properly, stabilizes proteins against heat stress, and aids in protein degradation...
    51 KB (5,537 words) - 04:59, 26 April 2024
  • Thumbnail for G protein-coupled receptor
    ten global best-selling drugs (Advair Diskus and Abilify) act by targeting G protein-coupled receptors. The exact size of the GPCR superfamily is unknown...
    82 KB (9,376 words) - 08:31, 7 March 2024
  • Thumbnail for Autophagy
    Autophagy (category Pages displaying short descriptions of redirect targets via Module:Annotated link)
    autophagy targeting protein. The autophagy proteins CALCOCO2/NDP52 and MAP1LC3/LC3 may have evolved specifically to target pathogens or pathogenic proteins for...
    75 KB (8,903 words) - 15:38, 17 April 2024