• Thumbnail for Pyrimidine dimer
    Cyclobutane pyrimidine dimer (CPD) is a dimer which features a four-membered ring formed by the fusion of two double-bonded carbons from adjacent pyrimidines. CPDs...
    16 KB (1,939 words) - 13:32, 25 March 2024
  • Thumbnail for Photolyase
    photolyase, dipyrimidine photolyase (photosensitive), and deoxyribonucleate pyrimidine dimer lyase (photosensitive). This enzyme belongs to the family of lyases...
    15 KB (1,773 words) - 12:32, 2 May 2024
  • Deoxyribonuclease (pyrimidine dimer) (EC 3.1.25.1, endodeoxyribonuclease (pyrimidine dimer), bacteriophage T4 endodeoxyribonuclease V, T4 endonuclease...
    2 KB (148 words) - 13:47, 26 August 2023
  • (BH3) occurs as the dimer diborane (B2H6), due to the high Lewis acidity of the boron center. In the context of polymers, "dimer" also refers to the degree...
    13 KB (1,372 words) - 08:00, 3 May 2024
  • endonucleosidase (EC 3.2.2.17, pyrimidine dimer DNA-glycosylase, endonuclease V, deoxyribonucleate pyrimidine dimer glycosidase, pyrimidine dimer DNA glycosylase, T4-induced...
    2 KB (165 words) - 13:47, 26 August 2023
  • Thumbnail for Germicidal lamp
    ultraviolet light disrupts DNA base pairing, causing formation of pyrimidine dimers, and leads to the inactivation of bacteria, viruses, and protozoans...
    8 KB (984 words) - 09:22, 9 September 2023
  • Thumbnail for Mutation
    replication, mitosis, or meiosis or other types of damage to DNA (such as pyrimidine dimers caused by exposure to ultraviolet radiation), which then may undergo...
    117 KB (13,965 words) - 23:04, 22 April 2024
  • to indicate that either pyrimidine nucleobase – C, T, or U – can be substituted at the indicated position. pyrimidine dimer A type of molecular lesion...
    253 KB (21,825 words) - 17:01, 13 May 2024
  • Thumbnail for Melanoma
    1/3rd the frequencies of UVA-induced thymine dimers, respectively. If unrepaired, cyclobutane pyrimidine dimer (CPD) photoproducts can lead to mutations...
    153 KB (15,963 words) - 11:33, 6 May 2024
  • of these UV-induced thymine dimers. Endonuclease V first cleaves the glycosylic bond on the 5’ side of a pyrimidine dimer and then catalyzes cleavage...
    25 KB (2,688 words) - 21:18, 6 April 2024
  • Thumbnail for DNA repair
    repair pathway to enter the chromatin and repair UV-induced cyclobutane pyrimidine dimer damages. After rapid chromatin remodeling, cell cycle checkpoints are...
    128 KB (15,713 words) - 22:17, 26 April 2024
  • Thumbnail for DDB2
    containing another UV light-induced photoproduct (the cyclobutane pyrimidine dimer), and binds weakly to DNA that has no DNA damage. The DDB2 component...
    16 KB (2,063 words) - 23:44, 9 September 2023
  • Thumbnail for Non-ionizing radiation
    induce cellular damage, and can be carcinogenic. Photochemistry such as pyrimidine dimer formation in DNA can happen through most of the UV band, including...
    22 KB (2,516 words) - 23:32, 16 May 2024
  • light, which introduces cyclobutane pyrimidine dimer damages in DNA, or psoralen-plus-light, which introduces pyrimidine adducts, the rate of mutation increases...
    9 KB (1,064 words) - 22:45, 12 January 2024
  • Thumbnail for Ultraviolet
    covalent bonds to form between adjacent pyrimidine bases, producing a dimer. Most UV-induced pyrimidine dimers in DNA are removed by the process known...
    112 KB (12,375 words) - 02:35, 19 April 2024
  • Copy/Paste Detector, software to find duplicate computer code Cyclobutane pyrimidine dimer, a common UV product Cyclopentadiene, an organic compound Cyproterone...
    2 KB (275 words) - 08:12, 16 May 2024
  • acid to truxillic acid. Many photodimers are now recognized, e.g. pyrimidine dimer, thiophosgene, diamantane. Another example was uncovered by Egbert...
    15 KB (1,891 words) - 02:09, 14 July 2023
  • Thumbnail for Photochemistry
    groups to molecules. DNA: photodimerization leading to cyclobutane pyrimidine dimers. Examples of photochemical organic reactions are electrocyclic reactions...
    26 KB (2,821 words) - 00:51, 14 May 2024
  • DNA photoproducts join two adjacent pyrimidines; the photoproduct is typically the cyclobutane pyrimidine dimer (CPD). Specificity for C>T appears to...
    39 KB (4,037 words) - 23:13, 8 March 2024
  • Thumbnail for Sirtuin 1
    DNA-templated negative regulation of cAMP-dependent protein kinase activity pyrimidine dimer repair by nucleotide-excision repair response to insulin histone H3-K9...
    26 KB (3,126 words) - 21:11, 9 May 2024
  • Thumbnail for William A. Haseltine
    Shaper NL; Grossman L (1980). "Cleavage of Pyrimidine Dimers in Specific DNA Sequences by a Pyrimidine Dimer DNA-Glycosylase of M.luteus". Nature. 285...
    95 KB (12,570 words) - 23:52, 23 March 2024
  • act by causing DNA damage - alterations in DNA structure such as pyrimidine dimers, or breakage of one or both DNA strands. DNA repair processes can...
    18 KB (2,174 words) - 10:58, 7 April 2024
  • photo dimers (CPD) are formed by photochemical reactions that result in the coupling of the C=C double bonds of pyrimidines. Thymine dimers (T-T dimers) formed...
    8 KB (658 words) - 16:57, 5 January 2024
  • Thumbnail for Xiphophorus
    (Gordon, 1932) (swordtail platyfish) Induction of DNA damage (e.g. pyrimidine dimers) by ultraviolet radiation, and the repair of such damage by photoreversal...
    17 KB (1,563 words) - 06:04, 10 February 2024
  • (UV) – Causes pyrimidine (T or C) nucleotide bases on the same strand to covalent join forming a pyrimidine dimer. Thymine-thymine dimers are the most...
    14 KB (1,634 words) - 22:56, 23 March 2024
  • Thumbnail for 5,6-Dihydro-5(α-thyminyl)thymine
    5,6-Dihydro-5(α-thyminyl)thymine (category Dimers (chemistry))
    is a DNA pyrimidine dimer photoproduct produced when DNA in bacterial spores is exposed to ultraviolet light. In bacteria, this DNA base dimer deforms...
    2 KB (198 words) - 07:43, 17 October 2022
  • component of sunlight that damages the DNA of somatic cells. Cyclobutane pyrimidine dimers (CPD) are a type of damage induced by UV-B. In A. thaliana, homologous...
    4 KB (553 words) - 22:21, 15 March 2024
  • light induces the formation of DNA damages including pyrimidine dimers (such as thymine dimers) and 6,4 photoproducts. These types of "bulky" damages...
    79 KB (9,956 words) - 11:19, 14 March 2024
  • Thumbnail for Action spectrum
    Region (385–405 nm) Damages Skin Cells and Induces "dark" Cyclobutane Pyrimidine Dimers in Human Skin in vivo". Scientific Reports. 8 (1): 12722. doi:10...
    6 KB (674 words) - 19:02, 25 April 2024
  • radiation with enough energy to excite certain molecular bonds to form pyrimidine dimers. This energy may be less than ionizing, but near to it. A good example...
    60 KB (6,551 words) - 00:51, 15 May 2024