• Thumbnail for RANKL
    Receptor activator of nuclear factor kappa-Β ligand (RANKL), also known as tumor necrosis factor ligand superfamily member 11 (TNFSF11), TNF-related activation-induced...
    28 KB (3,372 words) - 21:06, 8 March 2024
  • Rankl is a surname. Notable people with the surname include: George Rankl (1867–?), American politician Karl Rankl (1898–1968), Austrian-British conductor...
    281 bytes (74 words) - 23:32, 30 December 2020
  • Thumbnail for Denosumab
    joint and muscle pain in the arms or legs. Denosumab is an inhibitor of RANKL (receptor activator of nuclear factor kappa-Β ligand), which works by decreasing...
    25 KB (2,081 words) - 04:39, 30 April 2024
  • Thumbnail for Osteopetrosis
    (December 2012). "Osteopetrosis rescue upon RANKL administration to Rankl(-/-) mice: a new therapy for human RANKL-dependent ARO". Journal of Bone and Mineral...
    26 KB (2,736 words) - 09:45, 18 March 2024
  • George Rankl (February 28, 1867 in Milwaukee, Wisconsin – ?) was a member of the Wisconsin State Assembly Rankl was elected to the Assembly in 1902. He...
    915 bytes (49 words) - 01:43, 19 December 2022
  • Karl Rankl (1 October 1898 – 6 September 1968) was a British conductor and composer who was of Austrian birth. A pupil of the composers Schoenberg and...
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  • Thumbnail for Osteoprotegerin
    decoy receptor for receptor activator of nuclear factor kappa-B ligand (RANKL). OPG also binds to TNF-related apoptosis-inducing ligand (TRAIL) and inhibits...
    30 KB (3,686 words) - 09:12, 11 December 2023
  • Thumbnail for Parathyroid hormone
    expression of RANKL and inhibits their secretion of osteoprotegerin (OPG). Free OPG competitively binds to RANKL as a decoy receptor, preventing RANKL from interacting...
    34 KB (4,158 words) - 03:39, 8 April 2024
  • Thumbnail for RANK
    molecular sub-family. RANK is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation...
    23 KB (3,035 words) - 06:16, 25 December 2023
  • Thumbnail for Osteoclast
    monocyte/macrophage derived cells. RANKL is a member of the tumour necrosis family (TNF), and is essential in osteoclastogenesis. RANKL knockout mice exhibit a phenotype...
    26 KB (2,925 words) - 01:53, 25 March 2024
  • Robert A. Rankl (born c. 1976) is an American college football coach. He is the head football coach for Alfred University; a position he has held since...
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  • Thumbnail for Bone remodeling
    marrow-derived membrane and soluble cytokines and growth factors (e.g. M-CSF, RANKL, VEGF and IL-6 family). It is in this way that the body is able to maintain...
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  • Surface RANKL on osteoblasts as well as secreted RANKL provide necessary signals for osteoclast precursors to differentiate into osteoclasts. RANKL expression...
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  • Thumbnail for Cortisol
    decoy receptor and captures some RANKL before it can activate the osteoclasts through RANK. In other words, when RANKL binds to OPG, no response occurs...
    77 KB (8,516 words) - 23:51, 30 April 2024
  • Thumbnail for Arthritis
    pro-inflammatory cytokines and receptor activator of nuclear factor kappa B ligand (RANKL), a cell surface protein present in Th17 cells and osteoblasts. Osteoclast...
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  • conference on Computer and communications security, pp. 317–329. Wolfgang Rankl, Wolfgang Effing, Smart Card Handbook (2004) T. Welz: Smart cards as methods...
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  • Thumbnail for Tooth resorption
    cartilage and dentin. Receptive activator of nuclear factor kappa-B ligand (RANKL), also called osteoclast differentiation factor (ODF) and osteoprotegerin...
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  • Thumbnail for Tumor necrosis factor
    TNFSF6) GITRL (TNFSF18) LIGHT (HEVML, CD258, TNFSF14) OX40L (CD252, TNFSF4) RANKL (TRANCE, OPGL, ODF, CD254, TNFSF11) Siva (CD27BP) TRAIL (CD253, TNFSF10)...
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  • Thumbnail for Rheumatoid arthritis
    fibroblast-like synoviocytes, in the joint space. By signalling through RANKL and RANK, they eventually trigger osteoclast production, which degrades...
    146 KB (17,069 words) - 23:20, 26 April 2024
  • rescue-phenotype studies, RANKL is shown to be a receptor activator of NF-κB ligand and play a role in differentiation of M cells. RANKL is expressed throughout...
    12 KB (1,494 words) - 01:49, 7 September 2023
  • Thumbnail for Osteolytic lesion
    Denosumab, a monoclonal antibody treatment RANKl inhibitor that targets the osteocyte apoptosis regulatory RANKL gene, is also prescribed to prevent bone...
    6 KB (673 words) - 19:26, 15 September 2022
  • pluripotent cells in osteoblasts and inhibiting the RANKL/RANK pathway and osteoclastogenesis. RANKL is a member of the TNF superfamily of ligands. Through...
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  • Thumbnail for Osteoporosis
    Osteoprotegerin (OPG) binds RANKL before it has an opportunity to bind to RANK, and hence suppresses its ability to increase bone resorption. RANKL, RANK, and OPG...
    120 KB (13,419 words) - 06:33, 21 April 2024
  • Geoffrey Molyneux Palmer, Cecil Gray, Havergal Brian, Healey Wlllan and Karl Rankl. Fritz Hart wrote two operas based on the theme: Deirdre of the Sorrows...
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  • Thumbnail for Multiple myeloma
    overexpression of receptor activator for nuclear factor κ B ligand (RANKL) by bone marrow stroma. RANKL activates osteoclasts, which resorb bone. The resultant bone...
    127 KB (13,052 words) - 04:34, 19 March 2024
  • Thumbnail for The Royal Opera
    stars. Webster appointed a little-known Austrian, Karl Rankl, to the post. Before the war, Rankl had acquired considerable experience in charge of opera...
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  • Thumbnail for Progesterone
    downstream mediator of progesterone-induced lobuloalveolar maturation. RANKL knockout mice show an almost identical mammary phenotype to PR knockout...
    123 KB (11,590 words) - 02:03, 21 April 2024
  • The Lost People (1949) as Guest (uncredited) Golden Salamander (1950) as Rankl Night and the City (1950) as Kristo State Secret (1950) as Karl Theodor...
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  • Thumbnail for NF-κB
    (OPG), which is a decoy receptor homolog for RANK ligand (RANKL), inhibits RANK by binding to RANKL, and, thus, osteoprotegerin is tightly involved in regulating...
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  • Thumbnail for Smart card
    Archived from the original on 7 May 2006. Retrieved 20 December 2007. Rankl, W.; W. Effing (1997). Smart Card Handbook. John Wiley & Sons. ISBN 0-471-96720-3...
    115 KB (12,137 words) - 00:55, 27 April 2024