A radiosensitizer is an agent that makes tumor cells more sensitive to radiation therapy. It is sometimes also known as a radiation sensitizer or radio-enhancer...

Hilaris BS, Jones WB, Lewis JL (August 1983). "Metronidazole as a radiosensitizer and high-dose radiation in advanced vulvovaginal malignancies, a pilot...

437-438 (limited preview in Google Book Search). W. Rhomberg, J. Dunst: Radiosensitizer. In: H. J. Schmoll, K. Höffken, K. Possinger (Ed.): Kompendium Internistische...

Misonidazole is a radiosensitizer that was investigated in clinical trials. It was used in these trials for radiation therapy to cause normally resistant...

study cell proliferation in living tissues and has been studied as a radiosensitizer and diagnostic tool in people with cancer. During the S phase of the...

Thymidine is listed as a chemical teratogen. Iododeoxyuridine is a radiosensitizer and increases the amount of DNA damage received from ionizing radiation...

treating rhabdomyosarcoma and Ewing's sarcoma. It is also used as a radiosensitizer in adjunct to radiotherapies, since it can increase the radiosensitivity...

NVX-108 NuvOx Pharma In a Phase Ib/II clinical trial where it raises tumor oxygen levels prior to radiation therapy in order to radiosensitize them....

supply, causing a low-oxygen state known as hypoxia. Oxygen is a potent radiosensitizer, increasing the effectiveness of a given dose of radiation by forming...

Cell Cycle in Epidermal Growth Factor Receptor Inhibitor-Mediated Radiosensitization". Cancer Research. 69 (12): 5108–5114. doi:10.1158/0008-5472.CAN-09-0466...

poisons, but they act in different ways. Taxanes are also thought to be radiosensitizing. Hongdoushans A–C are oxygenated taxane diterpenes, isolated from the...

is a derivative of caffeine (a xanthine class), which is used as a radiosensitizer in the radiotherapy of tumors to increase the sensitivity of tumor...

needed] As of April 2022[update], nelfinavir is being studied as a radiosensitizing agent as part of treatment of advanced cervical cancer. "Viracept (nelfinavir...

highly resistant to radiotherapy. Various approaches to chemotherapy radiosensitizers have been pursued, with limited success as of 2016[update]. As of 2010[update]...

leaving the G1/S phase of the cell cycle. This agent also exhibits radiosensitizing activity by maintaining cells in the radiation-sensitive G1 phase and...

with established indications (malaria and auto-immune diseases). The radiosensitizing and chemosensitizing properties of chloroquine are being evaluated...

image-guided and intensity-modulated radiotherapy, radioprotectors, radiosensitizers, altered fractionation, combination chemoradiotherapy as well as combining...

KAN0438757) as a potent and highly selective PFKFB3 inhibitor and a radiosensitizer. Enhanced activity of PFKFB3 accelerates ROS production as an end product...

Screening Platform to Discover Associations of Molecular Targeted Radiosensitizers with Genomic Biomarkers". Molecular Cancer Research. 13 (4): 713–720...

Ater J, Mehta MP (January 2003). "A phase I study of topotecan as a radiosensitizer for brainstem glioma of childhood: first report of the Children's Cancer...

chemotherapy and other drugs. Drugs that increase the effect of radiotherapy (radiosensitizers) have shown no added benefit, but promising new agents are under investigation...

support. Thematic health programme. Radiotherapy Clinical application of radiosensitizers in cancer radiotherapy in Pakistan. Randomized clinical trial of radiotherapy...

and lonidamine could reduce the dose of temozolomide required for radiosensitization of brain tumours. A derivative of lonidamine, gamendazole, is in testing...

by drug developer Diffusion Pharmaceuticals for potential use as a radiosensitizer, increasing the susceptibility of hypoxic cancer cells to radiation...

(September 1999). "Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine". Cancer Research. 59 (17): 4375–4382. PMID 10485486...

repair, the relationship between impaired XRCC4 function and the radiosensitization of tumor cells has been investigated. For instance, it has been reported...

fractionation. Molecular targeting of the DNA repair pathway can lead to radiosensitization or radioprotection. Examples are direct and indirect inhibitors on...

preference in fixing double-strand breaks, then it may serve as a radiosensitizer, a molecule that increases the sensitivity of cells to radiation damage...

"Taselisib (GDC-0032), a Potent β-Sparing Small Molecule Inhibitor of PI3K, Radiosensitizes Head and Neck Squamous Carcinomas Containing Activating PIK3CA Alterations"...

have different RBE values. The presence of oxygen in a cell acts as a radiosensitizer, making the effects of the radiation more damaging. Tumor cells typically...