Regulation of gene expression, or gene regulation, includes a wide range of mechanisms that are used by cells to increase or decrease the production of...

modification of a protein. Regulation of gene expression gives control over the timing, location, and amount of a given gene product (protein or ncRNA)...

In biochemistry, in the biological context of organisms' regulation of gene expression and production of gene products, downregulation is the process by...

the regulation of gene expression. Gene expression can be controlled through the action of repressor proteins that attach to silencer regions of the DNA...

Gene silencing is the regulation of gene expression in a cell to prevent the expression of a certain gene. Gene silencing can occur during either transcription...

List of cis-regulatory RNA elements Polyadenylation signals, mRNA AU-rich element, mRNA Other Regulation of gene expression Cis-trans isomerism Gene regulatory...

segment of a nucleic acid molecule which is capable of increasing or decreasing the expression of specific genes within an organism. Regulation of gene expression...

proliferation. This gene also has a role in the formation of some cancers and in the regulation of gene expression. The H19 gene is expressed exclusively...

increase, or decrease the production or expression of specific gene products, such as RNA or proteins. Gene regulation increases an organism's versatility...

promoter regions of signal-regulated genes. These DSBs allow rapid up-regulation of expression of such signal responsive genes in a number of systems (see...

Its primary mode of action is the regulation of the iron storage hormone hepcidin. It is possible to delete part or all of a gene of interest in mice...

circadian rhythmicity of the gene's expression. CRE/CREB-mediated regulation of the AVP gene is activated through the cAMP activation of Ras signaling pathways...

Post-transcriptional regulation is the control of gene expression at the RNA level. It occurs once the RNA polymerase has been attached to the gene's promoter and...

source of genetic variability. They seem to play a particularly important role in the regulation of gene expression and the creation of RNA genes. This...

modification of heavy metals, regulation of gene expression, regulation of protein function, and RNA processing. In vitro methylation of tissue samples...

MeCP2 has been implicated in regulation of imprinted genes and loci that include UBE3A and DLX5. Reduced expression of MECP2 in Mecp2+/- neural stem...

operon is an example of repressible negative regulation of gene expression. The repressor protein binds to the operator in the presence of tryptophan (repressing...

regulating the expression of adjacent genes; hence these receptors are classified as transcription factors. The regulation of gene expression by nuclear receptors...

However, the amount of gene product produced in a cell is more commonly dependent on regulation of gene expression. The normal gene dosage is dependent on...

of high grade, ductal breast cancers. It has long been noted that loss of BRCA1 activity, either by germ-line mutations or by down-regulation of gene...

including the control of cell growth, cell proliferation, cell differentiation, and apoptosis. In humans, TGF-β1 is encoded by the TGFB1 gene. TGF-β is a multifunctional...

a tumor suppressor gene through the action of its phosphatase protein product. This phosphatase is involved in the regulation of the cell cycle, preventing...

heavily on proper expression of the SHH gene and subsequent sonic hedgehog protein, earning it the distinction of being an essential gene to development...

genetics, a regulator gene, regulator, or regulatory gene is a gene involved in controlling the expression of one or more other genes. Regulatory sequences...

deletion of the kir6.2 or sur2 genes leads to coronary artery vasospasm and death. Upon further exploration of sarcKATP's role in cardiac rhythm regulation, it...

substances in the cell to govern the gene expression levels of mRNA and proteins which, in turn, determine the function of the cell. GRN also play a central...

such as gene transcription, translation, regulation of gene expression and protein–protein interactions, as opposed to the static aspects of the genomic...

There are two gene expression processes: transcription (DNA to RNA) and translation (RNA to protein). The regulation of gene expression by environmental...

involved in regulating gene expression, an important process in synaptic plasticity. Glutamate binding to NMDA upregulates the production of N-cadherin’s intracellular...

Currently, many more functions of bacteria DNA binding proteins have been discovered, including the regulation of gene expression by histone-like nucleoid-structuring...