• The regulatory T cells (Tregs /ˈtiːrɛɡ/ or Treg cells), formerly known as suppressor T cells, are a subpopulation of T cells that modulate the immune system...
    80 KB (9,560 words) - 05:24, 25 March 2024
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    (such as T-helper1, T-helper2, T-helper17, regulatory T-cell), which is distinguished by the types of cytokines they secrete. Regulatory T cells are yet...
    71 KB (9,026 words) - 12:33, 26 April 2024
  • Whether T cells are genetically engineered or not, before re-infusion, lympho-depletion of the recipient is required to eliminate regulatory T cells as well...
    54 KB (5,399 words) - 07:13, 19 April 2024
  • Thumbnail for T helper cell
    The T helper cells (Th cells), also known as CD4+ cells or CD4-positive cells, are a type of T cell that play an important role in the adaptive immune...
    54 KB (6,597 words) - 22:40, 25 April 2024
  • 1 regulatory cells or Tr1 (TR1) cells are a class of regulatory T cells participating in peripheral immunity as a subsets of CD4+ T cells. Tr1 cells regulate...
    15 KB (1,883 words) - 15:45, 3 December 2023
  • These regulatory Th17 cells can be generated by TGF-beta plus IL-6 in vitro. Like conventional regulatory T cells (Treg), induction of regulatory Treg17...
    31 KB (3,564 words) - 14:56, 3 December 2023
  • Regulatory B cells (Bregs or Breg cells) represent a small population of B cells that participates in immunomodulation and in the suppression of immune...
    27 KB (2,952 words) - 15:06, 24 January 2024
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    as a master regulator of the regulatory pathway in the development and function of regulatory T cells. Regulatory T cells generally turn the immune response...
    28 KB (3,448 words) - 17:10, 16 April 2024
  • Gamma delta T cells (γδ T cells) are T cells that have a γδ T-cell receptor (TCR) on their surface. Most T cells are αβ (alpha beta) T cells with TCR composed...
    35 KB (4,473 words) - 22:09, 14 December 2023
  • immunoreceptors, chimeric T cell receptors or artificial T cell receptors—are receptor proteins that have been engineered to give T cells the new ability to...
    76 KB (8,019 words) - 21:29, 13 April 2024
  • Thumbnail for Cytotoxic T cell
    A cytotoxic T cell (also known as TC, cytotoxic T lymphocyte, CTL, T-killer cell, cytolytic T cell, CD8+ T-cell or killer T cell) is a T lymphocyte (a...
    31 KB (3,862 words) - 12:44, 14 February 2024
  • Thumbnail for Cytotoxic T-lymphocyte associated protein 4
    responses. CTLA-4 is constitutively expressed in regulatory T cells but only upregulated in conventional T cells after activation – a phenomenon which is particularly...
    30 KB (3,464 words) - 15:06, 15 March 2024
  • cells are incorporated within the naive T cell phenotype but are a different T cell subset (Treg, regulatory T cells; RTE, Recent Thymic emigrant). It is...
    9 KB (1,147 words) - 07:16, 18 July 2023
  • killer T (NKT) cells are a heterogeneous group of T cells that share properties of both T cells and natural killer cells. Many of these cells recognize...
    14 KB (1,648 words) - 09:58, 18 July 2023
  • of their B cell receptor. Some weakly self-recognizing T cells are alternatively differentiated into natural regulatory T cells (nTreg cells), which act...
    50 KB (6,024 words) - 06:02, 29 April 2024
  • tough Killer T Cell, despite having undergone T Cell training together with him. Regulatory T Cell (制御性T細胞, Seigyosei Tī Saibō) Voiced by: Saori Hayami...
    146 KB (7,254 words) - 19:32, 13 February 2024
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    damage. The role of regulatory T and regulatory B cells is to suppress CMI enough to prevent tissue damage. However, an excessive regulatory response can prevent...
    64 KB (7,880 words) - 03:27, 10 March 2024
  • Thumbnail for T-cell receptor
    The T-cell receptor (TCR) is a protein complex found on the surface of T cells, or T lymphocytes, that is responsible for recognizing fragments of antigen...
    43 KB (5,385 words) - 16:14, 9 April 2024
  • Thumbnail for Butyric acid
    differentiation of regulatory T cells. In particular, circulating butyrate prompts the generation of extrathymic regulatory T cells. The low-levels of...
    64 KB (6,341 words) - 17:09, 12 April 2024
  • Thumbnail for Interleukin 2
    CD4+ T cells and activated CD8+ T cells. Put shortly the function of IL-2 is to stimulate the growth of helper, cytotoxic and regulatory T cells. IL-2...
    43 KB (4,990 words) - 05:37, 29 April 2024
  • Memory T cells are a subset of T lymphocytes that might have some of the same functions as memory B cells. Their lineage is unclear. Antigen-specific memory...
    32 KB (3,781 words) - 12:49, 26 April 2024
  • Thymocyte (redirect from T cell selection)
    thymocyte is an immune cell present in the thymus, before it undergoes transformation into a T cell. Thymocytes are produced as stem cells in the bone marrow...
    21 KB (2,578 words) - 05:12, 7 January 2024
  • Thumbnail for Programmed cell death protein 1
    (programmed cell death) of antigen-specific T-cells in lymph nodes. Second, it reduces apoptosis in regulatory T cells (anti-inflammatory, suppressive T cells)....
    39 KB (5,008 words) - 23:44, 12 April 2024
  • of T cell in quiescence, ignorance of antigen and direct inactivation of effector T cells by either clonal deletion, conversion to regulatory T cells (Tregs)...
    24 KB (2,954 words) - 09:46, 28 April 2024
  • Thumbnail for Medullary thymic epithelial cells
    "autoreactive T cells" which recognize self antigens via their TCRs. Autoreactive T cells must be eliminated from the body or skewed into the T Regulatory cells (TRegs)...
    29 KB (3,544 words) - 07:37, 20 April 2024
  • Thumbnail for Fiona Powrie
    activity while CD4+OX22lo T cells contained regulatory activity and could prevent the pathogenic activity of CD4+OX22hi T cells These were foundational...
    10 KB (1,118 words) - 01:28, 24 December 2023
  • T cells or MHC class II in case of CD4+ T cells) to create proper interaction with antigen-presenting cell. Furthermore, TCRs of regulatory T cells (Treg...
    18 KB (2,157 words) - 09:30, 30 March 2024
  • characteristics of regulatory T cells in lupus patients do not differ from healthy patients. However, depletion of regulatory T cells results in more intense...
    24 KB (2,830 words) - 09:15, 19 March 2024
  • Th3 have been described both in mice and human as CD4+FOXP3− regulatory T cells. Th3 cells were first described in research focusing on oral tolerance...
    11 KB (1,235 words) - 01:34, 11 November 2023
  • Suppressor T cells are also known as CD25+–Foxp3+ regulatory T cells (nTregs), and reduce inflammation. Negoro T, Iinuma F, Watanabe M (February 1996). "Cellular...
    1 KB (163 words) - 14:30, 20 November 2023