Rofecoxib is a COX-2-selective nonsteroidal anti-inflammatory drug (NSAID). It was marketed by Merck & Co. to treat osteoarthritis, rheumatoid arthritis...
76 KB (8,141 words) - 21:10, 2 February 2024
reduces the risk of peptic ulceration and is the main feature of celecoxib, rofecoxib, and other members of this drug class. After several COX-2–inhibiting...
42 KB (4,944 words) - 11:56, 4 April 2024
heart attack. As a result, certain COX-2 selective inhibitors—such as rofecoxib—are no longer used due to the high risk of undiagnosed vascular disease...
104 KB (11,179 words) - 06:50, 16 May 2024
complicated upper gastrointestinal events are similar between two groups. Like rofecoxib's VIGOR trial, the MEDAL Program was also criticized, this time due to...
13 KB (1,155 words) - 22:44, 30 March 2024
became the building-block for synthesis of COX-2 inhibitors. Celecoxib and rofecoxib, the first COX-2 inhibitors to reach market, were based on DuP-697. It...
37 KB (4,463 words) - 13:48, 4 June 2023
(traditional NSAIDs block both versions in general). These drugs (such as rofecoxib, celecoxib, and etoricoxib) are equally effective analgesics when compared...
109 KB (5,952 words) - 21:22, 20 April 2024
advice to physicians regarding celecoxib's safety. The COX-2 inhibitor rofecoxib (Vioxx) was removed from the market in 2004 due to its risk. Like all...
60 KB (6,032 words) - 04:21, 7 February 2024
the dosage and its effects are comparable to human medications such as rofecoxib and piroxicam. Grapiprant has also been tested in humans, and was researched to...
11 KB (1,033 words) - 23:56, 28 March 2024
COX-2 inhibitors Celecoxib (+tramadol) Etoricoxib Lumiracoxib ‡ Parecoxib Rofecoxib ‡ Valdecoxib ‡ Fenamates Flufenamic acid Meclofenamic acid Mefenamic acid...
164 KB (17,150 words) - 02:53, 7 May 2024
of increased risks of heart attacks with the selective COX-2 inhibitor rofecoxib in 2004, attention has focused on all the other members of the NSAIDs...
55 KB (5,351 words) - 12:05, 16 May 2024
double-blind, clinical trial comparing the efficacy of nimesulide, celecoxib and rofecoxib in osteoarthritis of the knee". Drugs. 63 (Suppl 1): 37–46. doi:10...
18 KB (1,751 words) - 01:31, 31 January 2024
COX-2 inhibitors Celecoxib (+tramadol) Etoricoxib Lumiracoxib ‡ Parecoxib Rofecoxib ‡ Valdecoxib ‡ Fenamates Flufenamic acid Meclofenamic acid Mefenamic acid...
118 KB (11,403 words) - 06:45, 15 May 2024
effective for a small number of people. The COX-2 selective inhibitor rofecoxib was removed from the market in 2004, as cardiovascular events were associated...
130 KB (13,577 words) - 18:02, 21 April 2024
thromboxane unbalanced by prostacyclin (which is reduced by COX-2 inhibition). Rofecoxib (brand name Vioxx) was withdrawn in 2004 because of such concerns. Some...
15 KB (1,672 words) - 11:53, 28 December 2023
COX-2 inhibitors Celecoxib (+tramadol) Etoricoxib Lumiracoxib ‡ Parecoxib Rofecoxib ‡ Valdecoxib ‡ Fenamates Flufenamic acid Meclofenamic acid Mefenamic acid...
173 KB (16,045 words) - 18:38, 15 May 2024
COX-2 inhibitors Celecoxib (+tramadol) Etoricoxib Lumiracoxib ‡ Parecoxib Rofecoxib ‡ Valdecoxib ‡ Fenamates Flufenamic acid Meclofenamic acid Mefenamic acid...
123 KB (12,173 words) - 16:08, 13 May 2024
COX-2 inhibitors Celecoxib (+tramadol) Etoricoxib Lumiracoxib ‡ Parecoxib Rofecoxib ‡ Valdecoxib ‡ Fenamates Flufenamic acid Meclofenamic acid Mefenamic acid...
218 KB (22,181 words) - 04:20, 17 May 2024
A.; et al. (2000). "Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis". New England Journal...
35 KB (3,591 words) - 04:52, 5 April 2024
Tanaka W, et al. (October 2000). "Comparative inhibitory activity of rofecoxib, meloxicam, diclofenac, ibuprofen, and naproxen on COX-2 versus COX-1...
34 KB (3,082 words) - 09:40, 20 April 2024
Ramelteon Rasagiline Reboxetine Ribavirin Rimonabant Risperidone Rivastigmine Rofecoxib Ropinirole Rotigotine Rufinamide Selegiline Sertraline Sevoflurane Sulpiride...
26 KB (1,685 words) - 02:08, 21 February 2024
COX-2 inhibitors Celecoxib (+tramadol) Etoricoxib Lumiracoxib ‡ Parecoxib Rofecoxib ‡ Valdecoxib ‡ Fenamates Flufenamic acid Meclofenamic acid Mefenamic acid...
140 KB (13,643 words) - 21:49, 17 May 2024
COX-2 inhibitors Celecoxib (+tramadol) Etoricoxib Lumiracoxib ‡ Parecoxib Rofecoxib ‡ Valdecoxib ‡ Fenamates Flufenamic acid Meclofenamic acid Mefenamic acid...
117 KB (11,931 words) - 16:20, 21 April 2024
2017. Bresalier, RS (March 2005). "Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial". N. Engl. J. Med. 352 (11):...
117 KB (11,643 words) - 17:54, 9 May 2024
COX-2 inhibitors Celecoxib (+tramadol) Etoricoxib Lumiracoxib ‡ Parecoxib Rofecoxib ‡ Valdecoxib ‡ Fenamates Flufenamic acid Meclofenamic acid Mefenamic acid...
38 KB (3,439 words) - 07:03, 5 May 2024
COX-2 inhibitors Celecoxib (+tramadol) Etoricoxib Lumiracoxib ‡ Parecoxib Rofecoxib ‡ Valdecoxib ‡ Fenamates Flufenamic acid Meclofenamic acid Mefenamic acid...
80 KB (7,311 words) - 06:54, 15 May 2024
Etoricoxib Firocoxib Lumiracoxib Mavacoxib Parecoxib Polmacoxib Robenacoxib Rofecoxib Tilmacoxib Valdecoxib; Others/unsorted: Anitrazafen Clobuzarit Curcumin...
27 KB (2,425 words) - 09:25, 2 May 2024
Etoricoxib Firocoxib Lumiracoxib Mavacoxib Parecoxib Polmacoxib Robenacoxib Rofecoxib Tilmacoxib Valdecoxib; Others/unsorted: Anitrazafen Clobuzarit Curcumin...
18 KB (1,662 words) - 13:46, 31 March 2024
COX-2 inhibitors Celecoxib (+tramadol) Etoricoxib Lumiracoxib ‡ Parecoxib Rofecoxib ‡ Valdecoxib ‡ Fenamates Flufenamic acid Meclofenamic acid Mefenamic acid...
96 KB (10,073 words) - 04:52, 11 April 2024
COX-2 inhibitors Celecoxib (+tramadol) Etoricoxib Lumiracoxib ‡ Parecoxib Rofecoxib ‡ Valdecoxib ‡ Fenamates Flufenamic acid Meclofenamic acid Mefenamic acid...
25 KB (2,264 words) - 00:13, 31 March 2024
COX-2 inhibitors Celecoxib (+tramadol) Etoricoxib Lumiracoxib ‡ Parecoxib Rofecoxib ‡ Valdecoxib ‡ Fenamates Flufenamic acid Meclofenamic acid Mefenamic acid...
10 KB (632 words) - 06:14, 14 April 2024