In biology, scaffold proteins are crucial regulators of many key signalling pathways. Although scaffolds are not strictly defined in function, they are...

activate them separately, with the help of a scaffold protein Ste5 that is selectively recruited by the G-proteins of the mating pathway. The trick is that...

carboxysomes do not form. The α-carboxysomal scaffold protein is called CsoS2, and the β-carboxysomal scaffold protein is called CcmM. Though CsoS2 and CcmM...

the chromosome scaffold is the backbone that supports the structure of the chromosomes. It is composed of a group of non-histone proteins that are essential...

for the evolution, function, allostery and folding of protein compexes. A privileged scaffold is a molecular framework or chemical moiety that is statistically...

stored Scaffold (chemistry), the core structure of a compound or a class of compounds Scaffold protein, a regulator of cell signalling pathways Scaffold, a...

interact with one another in one or more larger protein complexes. If one of the components is missing, this protein complex cannot fulfil its function in the...

G proteins, also known as guanine nucleotide-binding proteins, are a family of proteins that act as molecular switches inside cells, and are involved...

discussed with regards to adaptor proteins: Pawson, T. (1997). "Signaling Through Scaffold, Anchoring, and Adaptor Proteins". Science. 278 (5346): 2075–2080...

increases Notch on the surface of the cell that continues as a stem cell. Scaffold protein Biosemiotics Molecular cellular cognition Crosstalk (biology) Bacterial...

membrane fractions. It has a role as a scaffold protein which cross-links and anchors Tight Junction (TJ) strand proteins, which are fibril-like structures...

Fus3 protein (a MAPK protein) and the phosphatase Ptc1. These proteins both attempt to control the 4 phosphorylation sites of Ste5, a scaffold protein with...

conserved. Hpo can bind to and phosphorylate Sav, which may function as a scaffold protein because this Hpo-Sav interaction promotes phosphorylation of Wts. Hpo...

protein IQGAP1 (IQGAP1) also known as p195 is a ubiquitously expressed protein that in humans is encoded by the IQGAP1 gene. IQGAP1 is a scaffold protein...

known as Scribble, SCRIBL, or Scribbled homolog (Drosophila), is a scaffold protein which in humans is encoded by the SCRIB gene. It was originally isolated...

interphase/mitosis transition. Scaffold proteins, DNA polymerase, Heterochromatin Protein 1 and Polycomb are common non-histone proteins. This classification group...

Microtubule associated scaffold protein 2 is a protein that in humans is encoded by the MTUS2 gene. GRCh38: Ensembl release 89: ENSG00000132938 – Ensembl...

the protein and further damage to the nervous system. The aggregation of phosphorylated α-Synuclein can be enhanced if a presynaptic scaffold protein, Sept4...

in Adaptor protein Scaffold protein Biosemiotics Cell signaling Gene regulatory network Hormonal imprinting Metabolic pathway Protein–protein interaction...

motifs of the RTK and recruits p85 via Grb2-associated binding (GAB) scaffold protein. The p110 subunit can also be recruited independently of p85. For example...

subunits: the DEAD-box RNA helicase eIF4A, the cap-binding protein eIF4E, and the large "scaffold" protein eIF4G. The mammalian eIF4F complex was first described...

biochemistry and pharmacology, receptors are chemical structures, composed of protein, that receive and transduce signals that may be integrated into biological...

separate scaffolding proteins, the delta domain of HK97 MCP, which faces toward the inside of the capsid, acts as a scaffold protein. A cylindrical opening...

mitochondrial is a protein that in humans is encoded by the ISCU gene. It encodes an iron-sulfur (Fe-S) cluster scaffold protein involved in [2Fe-2S]...

synthesized and released by neurons. Neuropeptides typically bind to G protein-coupled receptors (GPCRs) to modulate neural activity and other tissues...

of an oxygen-sensitive potassium channel coupled to an oxygen sensory protein in the rabbit lumenal membrane. They are hypothetically involved in regulating...

Pericentriolar material 1 protein TNKS, Tankyrase-1 TNKS2, Tankyrase-2 TUBE1, Tubulin epsilon chain PCNT, pericentrin, a matrix scaffold protein CDK5RAP2, cyclin...

parts of the embryo have different concentrations of hedgehog signaling proteins. The pathway also has roles in the adult. Diseases associated with the...

messengers. In the case of G protein-coupled receptors, the conformation change exposes a binding site for a G-protein. The G-protein (named for the GDP and...

inhibits Bad (a Bcl-2 family member), causing Bad to interact with the 14-3-3 scaffold, resulting in Bcl dissociation and thus cell survival. Akt also activates...