• a selenoprotein is any protein that includes a selenocysteine (Sec, U, Se-Cys) amino acid residue. Among functionally characterized selenoproteins are...
    10 KB (1,101 words) - 16:06, 7 April 2024
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    publications also as Se-Cys) is the 21st proteinogenic amino acid. Selenoproteins contain selenocysteine residues. Selenocysteine is an analogue of the...
    19 KB (1,974 words) - 02:47, 12 April 2024
  • In molecular biology, the protein domain selenoprotein P (SelP) is the only known eukaryotic selenoprotein that contains multiple selenocysteine (Sec)...
    5 KB (513 words) - 12:41, 14 July 2023
  • Thumbnail for Selenoprotein o
    Selenoprotein O is a protein that in humans is encoded by the SELENOO gene. This gene encodes a selenoprotein, pseudokinase selenoprotein-O(SelO), that...
    2 KB (274 words) - 00:02, 20 February 2024
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    prokaryotic selenoprotein families drive the evolution of selenocysteine, an amino acid. Selenium is incorporated into several prokaryotic selenoprotein families...
    95 KB (10,993 words) - 16:33, 1 May 2024
  • Thumbnail for Selenium in biology
    its biological functions through selenoproteins, which contain the amino acid selenocysteine. Twenty-five selenoproteins are encoded in the human genome...
    39 KB (4,442 words) - 22:21, 12 April 2024
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    SECIS elements are thus a fundamental aspect of messenger RNAs encoding selenoproteins, proteins that include one or more selenocysteine residues. In bacteria...
    7 KB (718 words) - 21:57, 14 March 2022
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    Jun; Holmgren, Arne; Khanna, Kum Kum (1 July 2007). "From Selenium to Selenoproteins: Synthesis, Identity, and Their Role in Human Health". Antioxidants...
    97 KB (10,074 words) - 22:06, 12 May 2024
  • Thumbnail for Low-density lipoprotein receptor-related protein 8
    that ApoER2 is involved in many interactions at the surface of cells. Selenoprotein P transports the trace element selenium from the liver to the testes...
    27 KB (3,439 words) - 10:00, 27 March 2024
  • recommendation is based on the full expression of plasma glutathione peroxidase. Selenoprotein P is a better indicator of selenium nutritional status, and full expression...
    14 KB (1,498 words) - 02:51, 1 January 2024
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    In 2003, a landmark paper described the identification of all known selenoproteins in humans: 25 in total. Similar analyses have been run for other organisms...
    30 KB (2,786 words) - 05:16, 27 April 2024
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    SEPP1 (category Selenoproteins)
    Selenoprotein P is a protein that in humans is encoded by the SEPP1 gene. This gene encodes a selenoprotein containing multiple selenocysteine (Sec) residues...
    10 KB (1,127 words) - 01:07, 13 April 2024
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    GPX4 (category Selenoproteins)
    selenium-containing enzymes, whereas GPX6 is a selenoprotein in humans with cysteine-containing homologues in rodents. In selenoproteins, the amino acid selenocysteine...
    18 KB (2,303 words) - 20:32, 27 March 2024
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    have been shown to be selenium-containing enzymes, whereas Gpx6 is a selenoprotein in humans with cysteine-containing homologues in rodents. Amyloid beta...
    6 KB (719 words) - 11:49, 27 February 2024
  • Thumbnail for SELENON
    SELENON (category Selenoproteins)
    Selenoprotein N is a protein that in humans is encoded by the SEPN1 gene. This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue...
    7 KB (884 words) - 12:34, 2 April 2024
  • Salvinorin-A – C23H28O8 Saponin Secretin Selenocysteine Selenomethionine Selenoprotein Serine Serine kinase Serotonin Skatole Signal recognition particle Somatostatin...
    12 KB (933 words) - 20:02, 10 May 2023
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    Mackrill JJ, Gunther D, Crawford T, Flanigan KM, et al. (August 2008). "Selenoprotein N is required for ryanodine receptor calcium release channel activity...
    106 KB (11,535 words) - 09:33, 25 April 2024
  • Thumbnail for Vitamin B6
    hydrogen selenide, which can then be used to incorporate selenium into selenoproteins. PLP is required for the conversion of tryptophan to niacin, so low...
    61 KB (6,858 words) - 22:27, 9 May 2024
  • Thumbnail for Glutathione peroxidase
    Glutathione peroxidase (category Selenoproteins)
    have been shown to be selenium-containing enzymes, whereas GPx6 is a selenoprotein in humans with cysteine-containing homologues in rodents. GPx1, GPx2...
    15 KB (1,577 words) - 08:28, 3 December 2023
  • Thumbnail for SEPW1
    SEPW1 (category Selenoproteins)
    Selenoprotein W is a protein that in humans is encoded by the SEPW1 gene. This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue...
    4 KB (525 words) - 18:06, 12 May 2024
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    specific locations of specific proteins as directed by the genetic code. Selenoprotein Canadian Reference Material of selenomethionine Whanger, P. D. (2002)...
    8 KB (646 words) - 10:44, 26 September 2023
  • structural motif in the selenocysteine insertion element of eukaryotic selenoprotein mRNAs". RNA. 2 (4): 367–379. PMC 1369379. PMID 8634917. Wray GA (March...
    30 KB (3,472 words) - 02:52, 18 February 2024
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    B.; Ryscavage, A.; Gladyshev, V.; Yuspa, S.; Hatfield, D. (2010). "Selenoproteins are essential for proper keratinocyte function and skin development"...
    45 KB (4,658 words) - 07:00, 26 April 2024
  • Thumbnail for Thressa Stadtman
    biochemist, notable for her discovery of selenocysteine, and her research on selenoproteins and bioenergetics. In addition she made significant advances in amino...
    5 KB (398 words) - 22:11, 18 July 2023
  • Thumbnail for Carrimycin
    (April 2023). "Carrimycin, a first in-class anti-cancer agent, targets selenoprotein H to induce nucleolar oxidative stress and inhibit ribosome biogenesis"...
    5 KB (274 words) - 09:52, 9 May 2024
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    beta RHO: rhodopsin visual pigment RIOX2: Ribosomal oxygenase 2 SELT: Selenoprotein T SENP7: Sentrin-specific protease 7 SERP1: Stress-associated endoplasmic...
    34 KB (1,978 words) - 16:11, 20 April 2024
  • Thumbnail for Alain Manceau
    to Hg(Sec)4 and very poorly soluble inorganic HgSe is catalyzed by selenoprotein P (SelP) within which nucleate clusters of Hgx(Sec,Se)y that grow, likely...
    30 KB (2,739 words) - 19:07, 12 May 2024
  • Thumbnail for Non-proteinogenic amino acids
    ISSN 1756-4646. Böck, A.; Forchhammer, K.; Heider, J.; Baron, C. (1991). "Selenoprotein synthesis: An expansion of the genetic code". Trends in Biochemical...
    27 KB (2,862 words) - 14:28, 22 April 2024
  • Thumbnail for Acetylcysteine
    Dikiy A, Kim HY, Gladyshev VN (2009). "Functions and evolution of selenoprotein methionine sulfoxide reductases". Biochimica et Biophysica Acta (BBA)...
    53 KB (5,251 words) - 03:22, 16 May 2024
  • Thumbnail for Tuatara
    tuatara genome has 26 genes that encode selenoproteins and 4 selenocysteine-specific tRNA genes. In humans, selenoproteins have a function of antioxidation,...
    87 KB (9,262 words) - 14:30, 12 May 2024