• Senescence (/sɪˈnɛsəns/) or biological aging is the gradual deterioration of functional characteristics in living organisms. Whole organism senescence...
    57 KB (7,511 words) - 13:29, 12 April 2024
  • Thumbnail for Cellular senescence
    Cellular senescence is a phenomenon characterized by the cessation of cell division. In their experiments during the early 1960s, Leonard Hayflick and...
    57 KB (6,395 words) - 02:55, 28 March 2024
  • Thumbnail for Negligible senescence
    Negligible senescence is a term coined by biogerontologist Caleb Finch to denote organisms that do not exhibit evidence of biological aging (senescence), such...
    14 KB (1,497 words) - 02:08, 15 April 2024
  • Thumbnail for Plant senescence
    Plant senescence is the process of aging in plants. Plants have both stress-induced and age-related developmental aging. Chlorophyll degradation during...
    15 KB (2,074 words) - 17:39, 11 January 2024
  • Thumbnail for Hayflick limit
    will divide between 40 and 60 times in cell culture before entering a senescence phase. This finding refuted the contention by Alexis Carrel that normal...
    16 KB (1,876 words) - 19:40, 20 April 2024
  • Thumbnail for Hydra (genus)
    reproduction is suggestive of senescence in hydra: comment on Martinez, D., "Mortality patterns suggest lack of senescence in hydra." Exp Gerontol 33, 217–25"...
    29 KB (3,310 words) - 18:35, 24 April 2024
  • Lemaître, Jean-François (2016-11-07). "Comparative analyses of longevity and senescence reveal variable survival benefits of living in zoos across mammals". Scientific...
    14 KB (647 words) - 10:52, 6 April 2024
  • Senescence-associated beta-galactosidase (SA-β-gal or SABG) is a hypothetical hydrolase enzyme that catalyzes the hydrolysis of β-galactosides into monosaccharides...
    6 KB (588 words) - 17:13, 6 April 2024
  • Thumbnail for Aubrey de Grey
    likely that cumulative damage to mitochondria is a significant cause of senescence, but not the single dominant cause.[citation needed] In 2005, de Grey...
    39 KB (3,909 words) - 09:09, 27 April 2024
  • Senescence-associated secretory phenotype (SASP) is a phenotype associated with senescent cells wherein those cells secrete high levels of inflammatory...
    36 KB (4,073 words) - 22:51, 9 April 2024
  • Strategies for engineered negligible senescence (SENS) is a range of proposed regenerative medical therapies, either planned or currently in development...
    17 KB (1,882 words) - 17:20, 19 February 2024
  • Biological immortality (category Senescence)
    bio-indefinite mortality) is a state in which the rate of mortality from senescence is stable or decreasing, thus decoupling it from chronological age. Various...
    21 KB (2,239 words) - 13:32, 1 May 2024
  • Bacterial senescence or bacterial aging refers to the gradual decrease in cellular function in individual bacteria as they increase in age. Indicators...
    12 KB (1,332 words) - 11:40, 4 April 2024
  • Thumbnail for Aging-associated diseases
    seen with increasing frequency with increasing senescence. They are essentially complications of senescence, distinguished from the aging process itself...
    24 KB (2,544 words) - 20:03, 9 April 2024
  • The societal effects of negligible senescence considers a scenario where negligible senescence is achieved on a societal wide level in humans. There is...
    7 KB (804 words) - 05:53, 20 September 2023
  • Thumbnail for P16
    protects against cancer while increasing the risks associated with cellular senescence. p16 is an inhibitor of cyclin-dependent kinases (CDK). It slows down...
    36 KB (4,236 words) - 01:25, 8 April 2024
  • 50 years of age have not been determined. A senolytic (from the words senescence and -lytic, "destroying") is among a class of small molecules under basic...
    22 KB (2,866 words) - 21:34, 23 April 2024
  • This timeline lists notable events in the history of research into senescence or biological aging, including the research and development of life extension...
    174 KB (17,253 words) - 16:22, 22 March 2024
  • Thumbnail for Fetal membranes
    concentration. Pathophysiology of the fetal membranes, such as microfractures, senescence of cells in the fetal membrane and inflammation can lead to an increased...
    16 KB (1,893 words) - 02:46, 30 April 2024
  • Senolytic (category Senescence in non-human organisms)
    A senolytic (from the words senescence and -lytic, "destroying") is among a class of small molecules under basic research to determine if they can selectively...
    26 KB (1,986 words) - 22:11, 23 March 2024
  • Thumbnail for Death
    Death (category Senescence)
    biological aging, known in life sciences as "senescence." Some organisms experience negligible senescence, even exhibiting biological immortality. These...
    118 KB (12,343 words) - 19:23, 4 April 2024
  • Hallmarks of aging (category Senescence)
    all living organisms experience a gradual and irreversible increase in senescence and an associated loss of proper function of the bodily systems. As aging...
    40 KB (4,312 words) - 19:06, 19 April 2024
  • Thumbnail for Chlorophyll
    do the mutants with a damaged regulatory system. The process of plant senescence involves the degradation of chlorophyll: for example the enzyme chlorophyllase...
    34 KB (3,446 words) - 22:30, 20 April 2024
  • Biotechnology Computing Palaeontology Quantum computing and communication Senescence research Sustainable energy research Environment Birding and ornithology...
    43 KB (3,806 words) - 18:37, 1 May 2024
  • Thumbnail for Ethylene (plant hormone)
    1935 that ethylene acts similar to auxins in causing plant growth and senescence of vegetative tissues. This established that ethylene is a plant hormone...
    33 KB (3,838 words) - 15:58, 26 April 2024
  • proteostasis, deregulated nutrient sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and altered intercellular communication." Oxidation...
    114 KB (12,498 words) - 03:31, 20 April 2024
  • Thumbnail for Jeanne Calment
    Longevity Ageing Old age Longevity myths Senescence aging-associated diseases degenerative diseases negligible senescence Gerontology biogerontology cognitive...
    46 KB (4,994 words) - 01:47, 30 April 2024
  • on how senescent cells influence aging and cancer — in particular the Senescence Associated Secretory Phenotype (SASP). Campisi was born on March 12, 1948...
    12 KB (1,458 words) - 14:32, 13 March 2024
  • Thumbnail for Red blood cell
    Red blood cells (RBCs), scientific name erythrocytes (from ancient Greek erythros 'red' and kytos 'hollow vessel', with -cyte translated as 'cell' in modern...
    64 KB (7,808 words) - 04:10, 4 April 2024
  • Thumbnail for Melanocytic nevus
    associated with telomere length and represent potential markers of a decreased senescence in vivo". Cancer Epidemiology, Biomarkers & Prevention. 16 (7): 1499–1502...
    28 KB (3,042 words) - 16:29, 27 January 2024