• Thumbnail for Silibinin
    Silibinin (INN), also known as silybin (both from Silybum, the generic name of the plant from which it is extracted), is the major active constituent...
    21 KB (2,232 words) - 03:22, 28 March 2024
  • Thumbnail for Silybum marianum
    silychristin, isosilychristin, silydianin) and one flavonoid (taxifolin). Silibinin, a semipurified fraction of silymarin, is primarily a mixture of 2 diastereoisomers...
    15 KB (1,710 words) - 17:11, 22 February 2024
  • Thumbnail for Amanita phalloides
    poisoning. A long-term clinical trial of intravenous silibinin began in the US in 2010. Silibinin prevents the uptake of amatoxins by liver cells, thereby...
    56 KB (6,378 words) - 10:10, 22 April 2024
  • Thumbnail for Amanita virosa
    silibinin, an extract from the blessed milk thistle (Silybum marianum), may be beneficial in reducing the effects of death cap poisoning. Silibinin prevents...
    23 KB (2,575 words) - 23:04, 18 April 2024
  • Thumbnail for Destroying angel
    hemoperfusion in two 8-hour sessions", some with "IV thioctic acid, others IV silibinin" and all received a "special diet". It was concluded that "...intensive...
    8 KB (894 words) - 22:51, 20 April 2024
  • Thumbnail for Α-Amanitin
    generally too late for this to be an option. Chemically modified silibinin, silibinin dihydrogen disuccinate disodium (trade name Legalon SIL) a solution...
    20 KB (2,166 words) - 02:25, 12 April 2024
  • Thumbnail for Thistle
    for seeds that yield vegetable oil and pharmaceutical compounds such as Silibinin. Other thistles that nominally are weeds are important honey plants, both...
    27 KB (2,875 words) - 15:47, 14 May 2024
  • Thumbnail for Amanita ocreata
    intravenous silibinin". Human Toxicology. 2 (2): 183–95. doi:10.1177/096032718300200203. PMID 6862461. S2CID 19805371. Carducci R; et al. (1996). "Silibinin and...
    22 KB (2,404 words) - 17:25, 27 February 2024
  • identified in Silybum marianum (milk thistle) silymarin complex include silibinin, silychristin, silydianin, dehydrosilybin, deoxysilycistin, deoxysilydianin...
    6 KB (644 words) - 01:15, 28 June 2023
  • Thumbnail for Mushroom poisoning
    1983). "Chemotherapy of Amanita phalloides poisoning with intravenous silibinin". Hum Toxicol. 2 (2): 183–95. doi:10.1177/096032718300200203. PMID 6862461...
    50 KB (5,539 words) - 10:34, 7 May 2024
  • Sodium bicarbonate Aspirin, TCAs with a wide QRS[clarification needed] I.V Silibinin Amatoxin ingestion Succimer, chemical name Dimercaptosuccinic acid (DMSA)...
    8 KB (523 words) - 16:40, 17 June 2023
  • Thumbnail for G2 phase
    not to G(2)-M Cell-cycle arrest : commentary re: A. K. Tyagi et al., Silibinin strongly synergizes human prostate carcinoma DU145 cells to doxorubicin-induced...
    22 KB (2,818 words) - 04:30, 7 December 2023
  • overdose; both NAC and milk-thistle (Silybum marianum) or its derivative silibinin are used in liver poisoning from certain mushrooms, notably Amanita phalloides...
    9 KB (886 words) - 21:32, 24 March 2024
  • Thumbnail for Hepatitis C virus
    NSP5A, and host-targeted compounds such as cyclophilin inhibitors and silibinin. Sofosbuvir for use against chronic hepatitis C infection was approved...
    54 KB (6,585 words) - 09:53, 7 March 2024
  • penicillin as well as supportive care in cases of hepatic and renal injury. Silibinin, a product found in milk thistle, is a potential antidote to amatoxin...
    27 KB (3,005 words) - 18:05, 12 March 2024
  • 1;12(19):5859-68. Son YG, Kim EH, Kim JY, Kim SU, Kwon TK, Yoon AR, Yun CO, Choi KS. Silibinin sensitizes human glioma cells to TRAIL-mediated apoptosis via DR5 up-regulation...
    5 KB (443 words) - 17:37, 9 February 2024
  • Silafed Silain silandrone (INN) Sildaflo Sildec sildenafil (INN) Silexin silibinin (INN) silicristin (INN) silidianin (INN) silmitasertib (INN) silperisone...
    4 KB (261 words) - 16:35, 20 March 2022
  • The molecular formula C25H22O10 may refer to: Silibinin, major active constituent of silymarin Umbilicaric acid, an organic polyphenolic carboxylic acid...
    325 bytes (55 words) - 17:37, 3 January 2021
  • delivery method involving the use of thermo-responsive hydrogels loaded with silibinin, a cancer drug for treating melanoma. At low temperatures, these thermo-responsive...
    48 KB (5,059 words) - 08:54, 12 April 2024
  • Thumbnail for Lepiota brunneoincarnata
    identified, and delay specific liver-protective measures. Intravenous silibinin has a role in reducing amanitin uptake. Other specific measures include...
    9 KB (974 words) - 19:44, 15 May 2024
  • Thumbnail for Amanita bisporigera
    serum creatinine levels. List of Amanita species List of deadly fungi Silibinin – a liver-protecting compound used in cases of Amanita mushroom poisoning...
    38 KB (3,967 words) - 22:42, 10 January 2024
  • Thumbnail for INSIG2
    also by REV-ERBalpha, a component of the circadian clockwork circuitry. Silibinin inhibits adipocyte differentiation through a potential up-regulation of...
    12 KB (1,582 words) - 16:02, 22 December 2023
  • Fucoxanthin (increases BDNF production and activates PKA/CREB pathway); Silibinin (Activate hippocampal ROS-BDNF-TrkB patway). Josephy-Hernandez, Sylvia;...
    34 KB (3,766 words) - 00:08, 27 April 2024