• Thumbnail for Sirolimus
    Sirolimus blocks this pathway. The safety and efficacy of sirolimus treatment of LAM were investigated in clinical trials that compared sirolimus treatment...
    68 KB (6,700 words) - 21:46, 24 April 2024
  • currently the only sirolimus-coated balloon globally approved with CE certification. It is the most clinically studied sirolimus-coated balloon for peripheral...
    14 KB (1,375 words) - 21:32, 12 March 2024
  • Thumbnail for Lymphangioma
    systemic medication, or through observation. Sirolimus is used to treat lymphangioma. Treatment with sirolimus can decrease pain and the fullness of venous...
    21 KB (2,399 words) - 07:31, 9 April 2024
  • Thumbnail for Manish Doshi
    Medical developed MagicTouch, the world’s first sirolimus-drug coated balloon (SCB). It is the only sirolimus-coated balloon globally approved with CE certification...
    6 KB (540 words) - 02:14, 12 February 2024
  • Thumbnail for Immunosuppressive drug
    Everolimus is an analog of sirolimus and also is an mTOR inhibitor. Zotarolimus is a semi-synthetic derivative of sirolimus used in drug-eluting stents...
    29 KB (3,309 words) - 04:27, 30 January 2024
  • Thumbnail for Hives
    medications (dapsone, sulfasalazine), immunosuppressants (cyclosporin, sirolimus) or other medications like omalizumab can be used. These options are explained...
    50 KB (5,738 words) - 12:25, 5 May 2024
  • Thumbnail for Everolimus
    needed] It is the 40-O-(2-hydroxyethyl) derivative of sirolimus and works similarly to sirolimus as an inhibitor of mammalian target of rapamycin (mTOR)...
    27 KB (2,534 words) - 23:12, 30 March 2024
  • Thumbnail for Drug-eluting stent
    and Drug Administration (FDA) were sirolimus-eluting stents (SES), which release a natural product called sirolimus, an immunosuppressant drug. SES were...
    136 KB (13,977 words) - 10:43, 5 April 2024
  • Thumbnail for Methylprednisolone
    triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin...
    57 KB (5,140 words) - 04:43, 3 April 2024
  • Thumbnail for MTOR inhibitors
    sites for mTOR and FKBP12. The bacterial natural product rapamycin or sirolimus, a cytostatic agent, has been used in combination therapy with corticosteroids...
    57 KB (6,276 words) - 20:45, 9 May 2024
  • provide a "scaffold" to open the artery. An anti-rejection-type medication, sirolimus, helps to limit the overgrowth of normal cells while the artery heals...
    2 KB (178 words) - 20:25, 12 March 2024
  • Thumbnail for Flucloxacillin
    triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin...
    23 KB (2,055 words) - 07:13, 14 March 2024
  • Thumbnail for Tacrolimus
    hypomagnesemia, hyperglycemia, diabetes mellitus, itching, lung damage (sirolimus also causes lung damage), and various neuropsychiatric problems such as...
    43 KB (4,357 words) - 07:40, 28 March 2024
  • Thumbnail for Leukopenia
    after, in particular, high-dose therapy. Immunosuppressive drugs, such as sirolimus, mycophenolate mofetil, tacrolimus, ciclosporin, leflunomide and TNF inhibitors...
    9 KB (828 words) - 17:16, 9 May 2024
  • Thumbnail for Lymphangioleiomyomatosis
    (mTORC1) led to successful use of rapamycin analog sirolimus in clinical trials and FDA approval of sirolimus for treatment of LAM. TSC1 and TSC2 form a tumor...
    100 KB (11,094 words) - 11:12, 6 March 2024
  • Thumbnail for Nephrology
    cyclophosphamide, ciclosporin, tacrolimus, everolimus, thymoglobulin and sirolimus. Newer, so-called "biologic drugs" or monoclonal antibodies, are also...
    24 KB (2,769 words) - 03:46, 31 March 2024
  • Thumbnail for Graft-versus-host disease
    substances that have been studied for GvHD treatment include, for example: sirolimus, pentostatin, etanercept, and alemtuzumab. In August 2017, the US FDA...
    37 KB (4,234 words) - 23:18, 18 January 2024
  • Thumbnail for Fentanyl
    triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin...
    171 KB (15,828 words) - 01:00, 9 May 2024
  • Thumbnail for Neurofibroma
    Sirolimus, a compound that inhibits mTOR signalling, is being studied to treat plexiform neurofibromas. The combination of erlotinib with sirolimus was...
    30 KB (3,257 words) - 16:02, 28 February 2024
  • Thumbnail for Rifampicin
    triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin...
    47 KB (4,718 words) - 23:03, 17 April 2024
  • Thumbnail for Scleroderma
    cyclophosphamide, mycophenolate, intravenous immunoglobulin, rituximab, sirolimus, alefacept, and the tyrosine kinase inhibitors, imatinib, nilotinib, and...
    38 KB (3,291 words) - 01:18, 9 May 2024
  • 2018). "Targeted therapy with a localised abluminal groove, low-dose sirolimus-eluting, biodegradable polymer coronary stent (TARGET All Comers): a multicentre...
    12 KB (908 words) - 23:10, 16 November 2023
  • Thumbnail for Nicotine
    triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin...
    134 KB (13,937 words) - 19:09, 8 May 2024
  • usually caused by the prolonged use of T cell suppressant drugs, such as sirolimus, tacrolimus, or ciclosporin. The Epstein-Barr virus, which infects >90%...
    7 KB (767 words) - 14:49, 28 March 2024
  • Thumbnail for Streptomyces hygroscopicus
    hygroscopicus can be used to produce several chemical compounds or enzymes. Sirolimus (also known as rapamycin) is an immunosuppressant that has been isolated...
    4 KB (298 words) - 13:29, 17 July 2023
  • Thumbnail for Fenbendazole
    triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin...
    6 KB (467 words) - 01:16, 2 May 2024
  • Thumbnail for Erythromycin
    triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin...
    41 KB (3,748 words) - 08:27, 27 April 2024
  • Thumbnail for Percutaneous coronary intervention
    drug-eluting stents to be utilized were the paclitaxel-eluting stent and the sirolimus-eluting stent, both of which have received approval from the U.S. Food...
    48 KB (5,366 words) - 05:44, 1 April 2024
  • Thumbnail for Rifaximin
    triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine SR-12813 Suberoylanilide Sulfisoxazole Suramin...
    25 KB (2,328 words) - 07:02, 24 March 2024
  • Thumbnail for Cardiac allograft vasculopathy
    after transplantation and on detection of CAV. Medications including sirolimus and everolimus can slow disease progression. A repeat heart transplantation...
    21 KB (1,955 words) - 14:52, 15 September 2023