• Thumbnail for Spätzle (gene)
    laureate Christiane Nüsslein-Volhard after the Spätzle noodle-like form of homozygous mutant fly larvae. Spätzle has a cystine knot structure supported by...
    4 KB (347 words) - 02:57, 31 October 2023
  • Thumbnail for Drosophila melanogaster
    Genetically modified insect Gynandromorphism JETLAG gene List of Drosophila databases Spätzle (gene) Time flies like an arrow; fruit flies like a banana...
    144 KB (16,575 words) - 05:34, 2 May 2024
  • containing pop culture references or puns. In the early days of genomics, genes were often given creative names upon discovery. A nomenclature committee...
    13 KB (792 words) - 22:05, 26 April 2024
  • Thumbnail for Toll-like receptor
    JM, Hoffmann JA (September 1996). "The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila...
    60 KB (6,685 words) - 09:55, 26 April 2024
  • Thumbnail for Drosophila embryogenesis
    follicle cells and the egg which results in the cleavage of the Toll-ligand Spätzle and activation of the Toll signaling cascade on the ventral side. Dorsal...
    21 KB (2,688 words) - 16:06, 23 March 2024
  • Thumbnail for Drosophila
    R-SNARE not normally found in synapses can substitute for synaptobrevin. The Spätzle protein is a ligand of Toll. In addition to melanin's more commonly known...
    61 KB (6,286 words) - 06:12, 28 April 2024
  • Thumbnail for Jules A. Hoffmann
    members in mammals being noted, study "The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila...
    14 KB (1,360 words) - 19:58, 29 April 2024
  • Thumbnail for NF-κB
    NF-κB (category Genes on human chromosome 4)
    JM, Hoffmann JA (September 1996). "The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila...
    89 KB (9,815 words) - 23:46, 26 April 2024
  • JM, Hoffmann JA (September 1996). "The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila...
    19 KB (2,182 words) - 05:09, 22 December 2023
  • dorsal depends on the amount of spätzle protein present. The third step is the regional expression of zygotic genes decapentaplegic (dpp), zerknüllt...
    33 KB (5,170 words) - 23:59, 3 January 2024
  • Thumbnail for Bruce Beutler
    Hoffmann, J. A. (September 20, 1996). "The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila...
    112 KB (12,100 words) - 21:52, 30 April 2024
  • Thumbnail for Drosomycin
    JM, Hoffmann JA (September 1996). "The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila...
    11 KB (1,251 words) - 18:37, 22 March 2024
  • Swiss chef, Mr. Smythe filled the menu with Germanic specialties like spatzle, beef and chocolate cake. For the Thais, he added country-style specialties...
    195 KB (19,067 words) - 09:35, 7 May 2024
  • Thumbnail for Imd pathway
    Imd pathway (category Genes)
    JM, Hoffmann JA (September 1996). "The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila...
    23 KB (2,455 words) - 19:21, 2 April 2024
  • Thumbnail for Bruno Lemaitre
    Jean-Marc; Hoffmann, Jules A. (1996-09-20). "The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila...
    16 KB (1,351 words) - 23:59, 8 May 2024
  • Reichhart JM, Hoffmann JA (1996). "The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila...
    75 KB (9,634 words) - 15:14, 28 February 2024
  • Thumbnail for Pamela Ronald
    Hoffmann, Jules A (September 1996). "The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila...
    45 KB (4,285 words) - 05:23, 22 April 2024
  • Thumbnail for Serpin
    and thus controls dorsoventral patterning. Easter functions to cleave Spätzle (a chemokine-type ligand), which results in toll-mediated signaling. As...
    136 KB (14,251 words) - 15:12, 4 May 2024
  • Thumbnail for Peptidoglycan recognition protein
    and activate a proteolytic cascade that generates an endogenous ligand Spätzle that activates cell-surface Toll-1 receptor. Toll-1 in turn triggers a...
    110 KB (11,846 words) - 05:41, 6 May 2024