• Thumbnail for Spike protein
    In virology, a spike protein or peplomer protein is a protein that forms a large structure known as a spike or peplomer projecting from the surface of...
    11 KB (1,091 words) - 01:27, 23 December 2023
  • Thumbnail for Coronavirus spike protein
    Spike (S) glycoprotein (sometimes also called spike protein, formerly known as E2) is the largest of the four major structural proteins found in coronaviruses...
    75 KB (7,376 words) - 12:14, 21 April 2024
  • Thumbnail for Myeloma protein
    such a protein are monoclonal protein, M protein, M component, M spike, spike protein, or paraprotein. This proliferation of the myeloma protein has several...
    7 KB (749 words) - 00:54, 14 March 2024
  • Look up Spike, spike, spikes, spiking, or spiky in Wiktionary, the free dictionary. Spike, spikes, or spiking may refer to: The Spike (novel), a novel...
    6 KB (838 words) - 20:00, 1 April 2024
  • Thumbnail for Coronavirus
    (E) and spike (S) structural proteins are anchored. The molar ratio of E:S:M in the lipid bilayer is approximately 1:20:300. The E and M protein are the...
    96 KB (10,566 words) - 13:12, 15 April 2024
  • Thumbnail for SARS-CoV-2
    SARS-CoV-2 has four structural proteins, known as the S (spike), E (envelope), M (membrane), and N (nucleocapsid) proteins; the N protein holds the RNA genome,...
    122 KB (12,474 words) - 22:56, 12 April 2024
  • Thumbnail for Bret Weinstein
    toxicity of spike proteins made from COVID-19 vaccines?". health-desk.org. Retrieved August 28, 2021. False claims about the toxicity of spike proteins from...
    36 KB (3,292 words) - 05:55, 13 April 2024
  • Thumbnail for SARS-related coronavirus
    spike (S) proteins are anchored. The spike proteins provide the virus with its bulbous surface projections, known as peplomers. The spike protein's interaction...
    52 KB (5,878 words) - 16:37, 17 January 2024
  • Thumbnail for Sanger sequencing
    used in efforts for public health initiatives such as sequencing the spike protein from SARS-CoV-2 as well as for the surveillance of norovirus outbreaks...
    27 KB (3,257 words) - 15:31, 12 April 2024
  • Thumbnail for Monoclonal antibody
    the pH at which a protein has no net charge. When the pH > pI, a protein has a net negative charge, and when the pH < pI, a protein has a net positive...
    47 KB (4,801 words) - 02:53, 9 April 2024
  • (NRP1) is a second protein that SARS-CoV-2 uses to enter human cells by binding to it with its spike protein next to the protein ACE2. 7 June – News...
    291 KB (28,416 words) - 23:38, 3 April 2024
  • Thumbnail for Variants of SARS-CoV-2
    its spike protein, compared to BA.1, which had already acquired 60 mutations since the ancestral Wuhan strain, including 32 in the spike protein. BA.2...
    228 KB (20,960 words) - 15:33, 22 April 2024
  • Thumbnail for Viral envelope
    bud particles even in the absence of spike proteins by relying only on viral core components. The spike proteins can occasionally be produced as virus-like...
    15 KB (1,972 words) - 13:47, 24 January 2024
  • that causes COVID-19, HIV has a spike protein. In retroviruses like HIV, the spike protein is formed by two proteins expressed by the Env gene. This viral...
    134 KB (15,824 words) - 14:29, 11 April 2024
  • Thumbnail for Rotavirus
    Rotavirus (section Proteins)
    A, Breton M, Fontanges P, Trugnan G, Chwetzoff S (2006). "Rotavirus spike protein VP4 binds to and remodels actin bundles of the epithelial brush border...
    86 KB (9,955 words) - 11:30, 26 March 2024
  • Thumbnail for Angiotensin-converting enzyme 2
    Angiotensin-converting enzyme 2 (category Single-pass transmembrane proteins)
    coronaviruses, including HCoV-NL63, SARS-CoV, and SARS-CoV-2. The SARS-CoV-2 spike protein itself is known to damage the endothelium via downregulation of ACE2...
    43 KB (5,100 words) - 15:32, 19 March 2024
  • structural proteins: major capsid protein F, major spike protein G, a small DNA-binding protein J (25 - 40 amino acids in length) and DNA pilot protein H. Assembly...
    17 KB (2,391 words) - 12:35, 30 January 2023
  • Thumbnail for Human coronavirus OC43
    genus Betacoronavirus, subgenus Embecovirus, an additional shorter spike protein called hemagglutinin-esterase (HE). Four HCoV-OC43 genotypes (A to D)...
    13 KB (1,455 words) - 15:28, 12 April 2024
  • individuals to shed coronavirus spike protein and affect menstruation and fertility in women exposed to them. However, the spike protein generated by vaccination...
    14 KB (1,408 words) - 16:27, 18 February 2024
  • Thumbnail for Oxford–AstraZeneca COVID-19 vaccine
    containing the full‐length codon‐optimised coding sequence of SARS-CoV-2 spike protein along with a tissue plasminogen activator (tPA) leader sequence. The...
    211 KB (16,862 words) - 19:31, 11 March 2024
  • Thumbnail for Betacoronavirus
    Several structures of the spike proteins have been resolved. The receptor binding domain in the alpha- and betacoronavirus spike protein is cataloged as InterPro: IPR018548...
    15 KB (1,479 words) - 01:17, 9 March 2024
  • Thumbnail for Alphacoronavirus
    virions with club-shaped surface projections formed by trimers of the spike protein, and a viral envelope. Alphacoronaviruses are in the subfamily Orthocoronavirinae...
    8 KB (861 words) - 17:21, 27 December 2023
  • Thumbnail for Human coronavirus HKU1
    of HCoV-HKU1 spike (S) and hemagglutinin esterase (HE) proteins have been resolved by Cryo-EM in 2016 and 2020, respectively. The S protein (PDB: 5I08​)...
    14 KB (1,637 words) - 17:55, 2 December 2023
  • Thumbnail for Zoonotic origins of COVID-19
    nucleotide identity across the spike protein. The observed binding of N-acetylneuraminic acid by the NTD of the spike protein and loss of that binding through...
    41 KB (5,118 words) - 22:55, 21 April 2024
  • focused on the coronavirus spike protein (S protein) and its variants as the primary antigen of COVID‑19 infection, since the S protein triggers strong B-cell...
    192 KB (21,930 words) - 19:29, 15 April 2024
  • Thumbnail for Furin
    fever, several filoviruses including ebola and marburg virus, and the spike protein of SARS-CoV-2, must be cleaved by furin or furin-like proteases to become...
    17 KB (2,288 words) - 15:22, 19 March 2024
  • Thumbnail for COVID-19
    structural proteins of SARS-CoV-2 include membrane glycoprotein (M), envelope protein (E), nucleocapsid protein (N), and the spike protein (S). The M protein of...
    285 KB (32,669 words) - 05:08, 20 April 2024
  • Thumbnail for Jason McLellan
    Vaccine Research Center to design a stabilized version of the SARS-CoV-2 spike protein, which biotechnology company Moderna used as the basis for the vaccine...
    30 KB (2,822 words) - 17:59, 15 February 2024
  • a recombinant virus type I with spike genes (S protein) replacement from FCoV by the canine coronavirus (CCoV) spikes. More recent research points to...
    31 KB (3,346 words) - 07:37, 5 April 2024
  • Thumbnail for List of therapeutic monoclonal antibodies
    vedotin mab chimeric/ humanized CD319 cancer Bamlanivimab mab human spike protein receptor binding domain (RBD) of SARS-CoV-2 Emergency Use Authorization...
    133 KB (3,983 words) - 02:16, 19 April 2024