• Thumbnail for Spike protein
    In virology, a spike protein or peplomer protein is a protein that forms a large structure known as a spike or peplomer projecting from the surface of...
    11 KB (1,091 words) - 15:33, 5 September 2024
  • Thumbnail for Coronavirus spike protein
    Spike (S) glycoprotein (sometimes also called spike protein, formerly known as E2) is the largest of the four major structural proteins found in coronaviruses...
    76 KB (7,457 words) - 08:55, 7 September 2024
  • Thumbnail for Myeloma protein
    such a protein are monoclonal protein, M protein, M component, M spike, spike protein, or paraprotein. This proliferation of the myeloma protein has several...
    6 KB (693 words) - 17:17, 28 August 2024
  • Thumbnail for Bret Weinstein
    toxicity of spike proteins made from COVID-19 vaccines?". health-desk.org. Retrieved August 28, 2021. False claims about the toxicity of spike proteins from...
    36 KB (3,299 words) - 19:14, 2 September 2024
  • Look up Spike, spike, spikes, spiking, or spiky in Wiktionary, the free dictionary. Spike, spikes, or spiking may refer to: The Spike (novel), a novel...
    6 KB (847 words) - 21:48, 16 September 2024
  • Thumbnail for Coronavirus
    (E) and spike (S) structural proteins are anchored. The molar ratio of E:S:M in the lipid bilayer is approximately 1:20:300. The E and M protein are the...
    96 KB (10,573 words) - 17:35, 11 September 2024
  • Thumbnail for SARS-CoV-2
    SARS-CoV-2 has four structural proteins, known as the S (spike), E (envelope), M (membrane), and N (nucleocapsid) proteins; the N protein holds the RNA genome,...
    122 KB (12,462 words) - 03:40, 15 August 2024
  • Thumbnail for SARS-related coronavirus
    spike (S) proteins are anchored. The spike proteins provide the virus with its bulbous surface projections, known as peplomers. The spike protein's interaction...
    52 KB (5,899 words) - 06:01, 22 August 2024
  • Thumbnail for Variants of SARS-CoV-2
    a category used for variants of the virus where mutations in their spike protein receptor binding domain (RBD) substantially increase binding affinity...
    223 KB (21,637 words) - 17:35, 18 September 2024
  • Thumbnail for Novavax COVID-19 vaccine
    Coalition for Epidemic Preparedness Innovations. It contains a recombinant spike protein from the SARS-CoV-2 Omicron variant lineage JN.1. The Novavax COVID‑19...
    73 KB (5,473 words) - 01:56, 17 September 2024
  • focused on the coronavirus spike protein (S protein) and its variants as the primary antigen of COVID‑19 infection, since the S protein triggers strong B-cell...
    200 KB (22,796 words) - 05:34, 12 September 2024
  • Thumbnail for Viral envelope
    bud particles even in the absence of spike proteins by relying only on viral core components. The spike proteins can occasionally be produced as virus-like...
    15 KB (1,972 words) - 13:47, 24 January 2024
  • Thumbnail for Monoclonal antibody
    the pH at which a protein has no net charge. When the pH > pI, a protein has a net negative charge, and when the pH < pI, a protein has a net positive...
    49 KB (4,964 words) - 04:02, 9 August 2024
  • Thumbnail for Zoonotic origins of COVID-19
    nucleotide identity across the spike protein. The observed binding of N-acetylneuraminic acid by the NTD of the spike protein and loss of that binding through...
    43 KB (5,157 words) - 12:11, 11 September 2024
  • Thumbnail for COVID-19
    structural proteins of SARS-CoV-2 include membrane glycoprotein (M), envelope protein (E), nucleocapsid protein (N), and the spike protein (S). The M protein of...
    288 KB (33,230 words) - 10:14, 12 September 2024
  • Thumbnail for Angiotensin-converting enzyme 2
    Angiotensin-converting enzyme 2 (category Single-pass transmembrane proteins)
    coronaviruses, including HCoV-NL63, SARS-CoV, and SARS-CoV-2. The SARS-CoV-2 spike protein itself is known to damage the endothelium via downregulation of ACE2...
    44 KB (5,225 words) - 03:19, 9 May 2024
  • individuals to shed coronavirus spike protein and affect menstruation and fertility in women exposed to them. However, the spike protein generated by vaccination...
    14 KB (1,408 words) - 16:27, 18 February 2024
  • Thumbnail for Sanger sequencing
    used in efforts for public health initiatives such as sequencing the spike protein from SARS-CoV-2 as well as for the surveillance of norovirus outbreaks...
    28 KB (3,344 words) - 18:55, 9 September 2024
  • that causes COVID-19, HIV has a spike protein. In retroviruses like HIV, the spike protein is formed by two proteins expressed by the Env gene. This viral...
    133 KB (15,784 words) - 05:42, 17 September 2024
  • Thumbnail for Jason McLellan
    Vaccine Research Center to design a stabilized version of the SARS-CoV-2 spike protein, which biotechnology company Moderna used as the basis for the vaccine...
    30 KB (2,822 words) - 17:59, 15 February 2024
  • Thumbnail for Alphacoronavirus
    virions with club-shaped surface projections formed by trimers of the spike protein, and a viral envelope. Alphacoronaviruses are in the subfamily Orthocoronavirinae...
    8 KB (861 words) - 17:21, 27 December 2023
  • Thumbnail for Rotavirus
    Rotavirus (section Proteins)
    A, Breton M, Fontanges P, Trugnan G, Chwetzoff S (2006). "Rotavirus spike protein VP4 binds to and remodels actin bundles of the epithelial brush border...
    86 KB (9,961 words) - 04:05, 4 September 2024
  • in January 2021 Here are some of the common mutations present in the spike protein of lineage B.1.617. Not all sublineages of B.1.617 share the same mutations:...
    10 KB (1,072 words) - 19:24, 23 August 2023
  • Thumbnail for Betacoronavirus
    Several structures of the spike proteins have been resolved. The receptor binding domain in the alpha- and betacoronavirus spike protein is cataloged as InterPro: IPR018548...
    15 KB (1,479 words) - 01:17, 9 March 2024
  • Thumbnail for Membrane fusion protein
    September 2016). "Structure, Function, and Evolution of Coronavirus Spike Proteins". Annual Review of Virology. 3 (1): 237–261. doi:10...
    11 KB (1,132 words) - 05:51, 6 May 2024
  • Thumbnail for Pfizer–BioNTech COVID-19 vaccine
    nucleoside-modified mRNA (modRNA) that encodes a mutated form of the full-length spike protein of SARS-CoV-2, which is encapsulated in lipid nanoparticles. Initial...
    260 KB (22,082 words) - 05:55, 13 September 2024
  • Thumbnail for NDV-HXP-S
    from the terms Newcastle disease virus, HexaPro, and spike protein. The stabilization of the S protein of SARS-CoV-2 (HexaPro) was achieved by Jason McLellan...
    14 KB (1,165 words) - 21:02, 26 August 2024
  • Thumbnail for Oxford–AstraZeneca COVID-19 vaccine
    into mRNA and the translation into spike protein. The approach to use adenovirus as a vector to deliver spike protein is similar to the approach used by...
    214 KB (17,080 words) - 22:39, 12 September 2024
  • Thumbnail for Coronavirus membrane protein
    M protein molecules as well as with the other three structural proteins, the envelope (E), spike (S), and nucleocapsid (N) proteins. The M protein is...
    19 KB (1,900 words) - 05:36, 19 April 2024
  • a recombinant virus type I with spike genes (S protein) replacement from FCoV by the canine coronavirus (CCoV) spikes. More recent research points to...
    31 KB (3,348 words) - 04:56, 15 July 2024