Transforming growth factor beta (redirect from TGF-β) (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes three different mammalian isoforms (TGF-β 1... 72 KB (8,680 words) - 21:20, 6 April 2024 |
transforming growth factor receptor 3 (TGFBR3) is the most abundant of the TGF-β receptors yet, it has no known signaling domain. It however may serve to... 20 KB (2,098 words) - 00:36, 28 November 2023 |
affinity for TGFβ2. TGFβR3 (β-glycan) has a high affinity for both homodimeric TGFβ1 and TGFβ2 and in addition the heterodimer TGF-β1.2. The TGFβ receptors... 4 KB (334 words) - 01:11, 14 December 2022 |
Upstream and downstream (transduction) (section TGF-β) type II and type I kinase receptors binding to the TGF-β ligands. Transforming growth factor-β (TGF-β) is a superfamily of cytokines that play a significant... 7 KB (826 words) - 05:06, 28 November 2023 |
Paracrine signaling (section TGF-β superfamily) fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective receptor initiates... 46 KB (4,940 words) - 22:55, 3 December 2023 |
primarily located in the cytoplasm, but accumulate in the nucleus following TGF-β signaling, where they can bind to DNA and regulate transcription. However... 35 KB (4,581 words) - 08:50, 23 March 2024 |
fibrillin-1 results in elevated TGF-β levels that directly correlate to MFS. Transforming growth factor beta (TGF-β) is a paracrine regulatory protein... 29 KB (3,707 words) - 23:15, 8 January 2024 |
Transforming growth factor beta (TGF-β) is a potent cell regulatory polypeptide homodimer of 25kD. It is a multifunctional signaling molecule with more... 20 KB (2,412 words) - 15:51, 5 October 2022 |
Transforming growth factor beta superfamily (redirect from TGF β superfamily) factor beta (TGF-β) superfamily is a large group of structurally related cell regulatory proteins that was named after its first member, TGF-β1, originally... 7 KB (595 words) - 14:53, 18 November 2022 |
gene forms a heteromeric complex with type II TGF-β receptors when bound to TGF-β, transducing the TGF-β signal from the cell surface to the cytoplasm... 14 KB (1,618 words) - 02:37, 2 April 2024 |
are involved in promoting metastatic events. Several signaling pathways (TGF-β, FGF, EGF, HGF, Wnt/beta-catenin and Notch) and hypoxia may induce EMT.... 59 KB (6,831 words) - 04:21, 1 April 2024 |
Osteochondroprogenitor cell (section TGF-β) the proximal region. TGF-β is important for cell proliferation and differentiation during skeletogenesis. During this process, TGF-β can stimulate differentiation... 14 KB (1,506 words) - 18:01, 3 November 2023 |
domain binds TGF-beta family ligands and its heparan sulfate chains bind bFGF. It acts as a reservoir of ligand for TGF-beta receptors. TGFβR3 (β-glycan) "Prosite... 5 KB (468 words) - 03:56, 29 November 2023 |
secretion of anti-inflammatory cytokine transforming growth factor beta (TGF-β). Th3 have been described both in mice and human as CD4+FOXP3− regulatory... 11 KB (1,235 words) - 01:34, 11 November 2023 |
growth factor, either of two classes of polypeptide growth factors (TGF-α and TGF-β) Terrestrial gamma-ray flash, a burst of gamma rays produced in the... 912 bytes (164 words) - 03:45, 22 May 2023 |
Death-associated protein 6 (section TGF-β regulated) Daxx interacts with the TGF-β type II receptor by binding of C-terminal domain of the protein. When the cell is treated with TGF-β, HIPK2, a nuclear kinase... 11 KB (1,528 words) - 20:53, 21 December 2023 |
Transforming growth factor beta (TGF-β) plays an important role in MFS. Fibrillin-1 directly binds a latent form of TGF-β, keeping it sequestered and unable... 73 KB (6,826 words) - 12:29, 4 May 2024 |
MECOM (section TGF-β and cell cycle progression) downstream signaling pathway of transforming growth factor beta (TGF-β). TGF-β, along with other TGF-β family ligands such as bone morphogenic protein (BMP) and... 37 KB (4,864 words) - 12:57, 5 January 2024 |
preventing the inappropriate trafficking of the receptor into the nucleus. TGF-β cytokines are members of a signaling protein family that includes activin... 52 KB (5,962 words) - 10:06, 3 May 2024 |
Transforming growth factor, beta 3 (redirect from TGF beta 3) which includes the TGF-β family, Bone morphogenetic proteins (BMPs), growth and differentiation factors (GDFs), inhibins and activins. TGF-β3 is believed... 15 KB (1,815 words) - 23:18, 18 August 2023 |
Research has found that the cytokine transforming growth factor beta (TGF-β) is essential for Treg cells to differentiate from naïve CD4+ cells and... 80 KB (9,560 words) - 05:24, 25 March 2024 |
liver regeneration process is completed, TGF-β puts an end to the proliferation phase by inducing apoptosis. TGF-β is the most important anti-proliferative... 22 KB (2,472 words) - 01:46, 10 April 2024 |
cytoplasm upon TGF-β stimulation. SMAD7 inhibits TGF-β signaling by preventing formation of Smad2/Smad4 complexes which initiate the TGF-β signaling. It... 23 KB (2,851 words) - 04:18, 25 March 2024 |
and the proliferation of tendon cells. The three isoforms of TGF-β (TGF-β1, TGF-β2, TGF-β3) are known to play a role in wound healing and scar formation... 45 KB (5,121 words) - 23:41, 29 March 2024 |