Thalidomide, sold under the brand names Contergan and Thalomid among others, is an oral medication used to treat a number of cancers (e.g., multiple myeloma)...

In the late 1950s and early 1960s, the use of thalidomide in 46 countries by women who were pregnant or who subsequently became pregnant resulted in the...

appendage. A prominent cause of phocomelia is the mother's use of the drug thalidomide during pregnancy; however, the causes of most cases are to be determined...

considered a side effect. For information regarding birth defects, see thalidomide. Somnolence (drowsiness; ~40%) Edema (~60%) Hypotension (low blood pressure)...

Chemical agents Prescription and recreational drugs (e.g., alcohol, thalidomide) Environmental toxins and contaminants (e.g., heavy metals such as mercury...

immune responses) containing an imide group. The IMiD class includes thalidomide and its analogues (lenalidomide, pomalidomide, mezigdomide and iberdomide)...

the U.S. Food and Drug Administration (FDA), she refused to authorize thalidomide for market because she had concerns about the lack of evidence regarding...

example of the importance of stereochemistry relates to the thalidomide disaster. Thalidomide is a pharmaceutical drug, first prepared in 1957 in Germany...

English rock musician, actor, writer and performance artist. He has thalidomide-induced phocomelia. Between 1980 and 1995 Fraser was a drummer with several...

Wonder Drug: The Secret History of Thalidomide in America and Its Hidden Victims is a nonfiction book authored by Jennifer Vanderbes and published by...

is a Canadian paralympic gold medallist swimmer, thalidomide survivor, and president of the Thalidomide Victims Association of Canada. Lake was born in...

the teratogenic drug thalidomide, marketed as the sleeping pill Contergan and promoted as a morning sickness preventive. Thalidomide caused severe birth...

1962) is an English thalidomide survivor and activist. She is a past chair of the National Advisory Committee of the Thalidomide Trust, the organisation...

a British thalidomide survivor, painter, lace maker, and carriage driver with the RDA. Mercer was a representative of the global thalidomide community...

Australian obstetrician. He published a letter on the teratogenicity of thalidomide following the findings of a midwife named Pat Sparrow, which resulted...

Thalidomide!! A Musical is a British musical written and composed by Mat Fraser, who was born with phocomelia as a result of the drug thalidomide being...

adjusted in people with kidney problems. Lenalidomide is closely related to thalidomide, which is known to cause severe birth defects, so its use during pregnancy...

thalidomide was first made available on 1 October 1957, and it became the second best-selling medication in Germany after Bayer Aspirin. Thalidomide was...

following the thalidomide disaster the development and licensing of drugs changed dramatically. First synthesized in 1953, thalidomide was widely prescribed...

the other enantiomer is harmful, like salbutamol and thalidomide. The (R) enantiomer of thalidomide is effective against morning sickness, while the (S)...

gain support for the survivors of thalidomide. Her efforts resulted in life-time compensation for Canadian "thalidomiders", as well as a special fund for...

deficiency), drugs (e.g. anticancer drugs, tetracyclines, many hormones, thalidomide), and environmental chemicals (e.g. mercury, lead, dioxins, PBDEs, HBCD...

wildly in their pharmacokinetic, pharmacodynamic profile. The tragedy of thalidomide illustrates the potential for extreme consequences resulting from the...

activity of thalidomide in the chick and zebrafish was cast into doubt due to a 2013 report that pomalidomide (a more potent thalidomide analogue) does...

compound of pomalidomide, thalidomide, was originally discovered to inhibit angiogenesis in 1994. Based upon this discovery, thalidomide was taken into clinical...

response to the thalidomide tragedy, in which thousands of children were born with birth defects as a result of their mothers taking thalidomide for morning...

1939) is a London art dealer and Thalidomide parent activist. He is the father of a daughter, Louise, disabled by thalidomide. Mason was educated at Highgate...

The act was introduced following problems with the off-label use of thalidomide. The act established the forerunner to the actual Commission on Human...

are the major side effects of thalidomide and lenalidomide. Lenalidomide causes more myelosuppression, and thalidomide causes more sedation. Chemotherapy-induced...

seek compensation for mothers who had taken the morning sickness drug thalidomide, which led to their children having severely deformed limbs. In 1984...