 | Tankyrase, also known as tankyrase 1, is an enzyme that in humans is encoded by the TNKS gene. It inhibits the binding of TERF1 to telomeric DNA. Tankyrase... 12 KB (1,493 words) - 17:10, 2 December 2023 |
 | Tankyrase-2 is an enzyme that in humans is encoded by the TNKS2 gene. TNKS2 has been shown to interact with GRB14, TERF1 and Cystinyl aminopeptidase.... 7 KB (822 words) - 06:18, 5 January 2024 |
 | of a tankyrase-binding motif shared by IRAP, TAB182, and human TRF1 but not mouse TRF1. NuMA contains this RXXPDG motif and is a novel tankyrase partner"... 9 KB (1,092 words) - 11:10, 18 August 2023 |
 | tyrosine-protein kinase LCK PCM1, Pericentriolar material 1 protein TNKS, Tankyrase-1 TNKS2, Tankyrase-2 TUBE1, Tubulin epsilon chain PCNT, pericentrin, a matrix scaffold... 3 KB (341 words) - 17:13, 12 February 2023 |
 | structure and function within the cell. PARP1, PARP2, VPARP (PARP4), Tankyrase-1 and -2 (PARP-5a or TNKS, and PARP-5b or TNKS2) have a confirmed PARP... 25 KB (3,085 words) - 15:29, 26 August 2023 |
 | inhibitor 1), TINF2 (TERF1-interacting telomerase nuclear factor), TNKS2 (Tankyrase, an enzyme) and NME1 (nucleoside diphosphate kinase).In conclusion, as... 20 KB (2,474 words) - 11:36, 23 December 2023 |
 | 182 kDa tankyrase-1-binding protein is an enzyme that in humans is encoded by the TNKS1BP1 gene. TNKS1BP1 has been shown to interact with TNKS. GRCh38:... 6 KB (663 words) - 00:53, 4 March 2023 |
 | Immortality Maximum life span Rejuvenation (aging) Senescence, biological aging Tankyrase Telomere-binding protein G-quartet Immortal DNA strand hypothesis During... 43 KB (4,840 words) - 12:55, 29 February 2024 |
| that results in decreased proteasome activity. (ADP-ribosyl)transferase Tankyrase (TNKS) causes ADP-ribosylation of PI31 which in turn increases the proteasome... 29 KB (3,535 words) - 13:23, 4 January 2024 |
 | Importantly, activity in the β-catenin destruction complex can be increased by tankyrase inhibitors and are a potential therapeutic option to reduce the growth... 11 KB (1,422 words) - 12:33, 24 December 2023 |
 | and a C-terminal SH3 domain. This protein binds sorting nexin 2 (SNX2), tankyrase (TNKS), and dynamin; an interaction between this protein and formin has... 9 KB (1,123 words) - 04:56, 29 April 2024 |
 | Importantly, activity in the β-catenin destruction complex can be increased by tankyrase inhibitors and are a potential therapeutic option to reduce the growth... 17 KB (2,157 words) - 03:32, 9 May 2024 |
 | 1074/jbc.M312309200. PMID 14715659. Ye JZ, de Lange T (Jun 2004). "TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex". Nature... 9 KB (1,095 words) - 10:20, 4 January 2024 |
 | Protein 131 yes TMOD3 TMOD3 Tropomodulin-3 TNKS PARP-5a Tankyrase TNKS1BP1 TNKS1BP1 182 kDa tankyrase-1-binding protein yes TNPO1 Transportin-1 Transportin-1/Karyopherin... 184 KB (12,548 words) - 05:28, 27 April 2024 |
 | PMC 1069602. PMID 15798198. Bae J, Donigian JR, Hsueh AJ (February 2003). "Tankyrase 1 interacts with Mcl-1 proteins and inhibits their regulation of apoptosis"... 13 KB (1,490 words) - 19:54, 2 January 2024 |
 | Sutherland G R; Daly R J (May 2001). "Identification of a novel human tankyrase through its interaction with the adaptor protein Grb14". J. Biol. Chem... 10 KB (1,043 words) - 21:05, 3 March 2023 |
Audrey; Meyer, Tobias N.; Lee, Ray M.; Chi, Nai-Wen (August 2005). "Tankyrase-1 overexpression reduces genotoxin-induced cell death by inhibiting PARP1"... 31 KB (3,633 words) - 00:02, 24 April 2024 |
| of a tankyrase-binding motif shared by IRAP, TAB182, and human TRF1 but not mouse TRF1. NuMA contains this RXXPDG motif and is a novel tankyrase partner"... 9 KB (1,140 words) - 23:08, 6 April 2024 |
 | (Transmembrane protein 31), SPAG9 (sperm associated antigen 9) and TNKS (tankyrase-1) are predicted to interact with TMEM44. TMEM44 undergoes threonine,... 9 KB (800 words) - 01:05, 10 March 2024 |
| "The formin-binding protein 17, FBP17, binds via a TNKS binding motif to tankyrase, a protein involved in telomere maintenance". FEBS Letters. 554 (1–2):... 8 KB (1,067 words) - 22:55, 27 March 2024 |
telomere lengthening is required, TRF1 recruits helicases and interacts with tankyrases to facilitate the process. TRF1 is highly expressed in stem cells, and... 21 KB (2,334 words) - 22:51, 9 April 2024 |
neuroscience 2012 December; 15(12): pages 1621–1623. Casaccia P. Anti-TANKyrase weapons promote myelination. Nature neuroscience 2011 August; 14(8): pages... 22 KB (2,607 words) - 01:32, 27 April 2024 |
– poly(adp-ribose) polymerases MeSH D08.811.913.400.725.115.690.840 – tankyrases MeSH D08.811.913.400.725.115.845 – sirtuins MeSH D08.811.913.400.725.130... 158 KB (15,232 words) - 06:41, 8 March 2024 |