A telomere (/ˈtɛləmɪər, ˈtiːlə-/; from Ancient Greek τέλος (télos) 'end', and μέρος (méros) 'part') is a region of repetitive nucleotide sequences associated...

The relationship between telomeres and longevity and changing the length of telomeres is one of the new fields of research on increasing human lifespan...

ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres. A telomere is a region of repetitive sequences at each...

Telomeres, the caps on the ends of eukaryotic chromosomes, play critical roles in cellular aging and cancer. An important facet to how telomeres function...

A telomere is a region of repetitive nucleotide sequences at each end of a chromosome. Telomere may also refer to: Telomere (insect morphology), a type...

cell undergoes mitosis, the telomeres on the ends of each chromosome shorten slightly. Cell division will cease once telomeres shorten to a critical length...

Telomere-binding proteins (also known as TERF, TRBF, TRF) function to bind telomeric DNA in various species. In particular, telomere-binding protein refers...

of telomeres is now clearly evident: lengthen the telomeres, lengthen the life. However, a study of the comparative biology of mammalian telomeres indicated...

Lengthening of Telomeres (also known as "ALT") is a telomerase-independent mechanism by which cancer cells avoid the degradation of telomeres. At each end...

California, Berkeley. Greider pioneered research on the structure of telomeres, the ends of the chromosomes. She was awarded the 2009 Nobel Prize for...

1984, Blackburn co-discovered telomerase, the enzyme that replenishes the telomere, with Carol W. Greider. For this work, she was awarded the 2009 Nobel Prize...

A telomere (pl.; telomeres or telomeron), literally "end piece", is a term in insect morphology, and refers to a type of "genital clasper"; i.e.: in Mallophaga...

distinct subgroup of RNA-dependent polymerases. Telomerase lengthens telomeres in DNA strands, thereby allowing senescent cells that would otherwise...

complex specialized DNA protective packages called telomeres that prevent DNA repair activities. Telomeres and mitotic DSBs have different functionality,...

chromosomes. Named regions include: Arms (p and q) Centromere Kinetochore Telomere Sub telomere satellite chromosome or trabant. NOR region During cell division...

A mega-telomere (also known as an ultra-long telomere or a class III telomere), is an extremely long telomere sequence that sits on the end of chromosomes...

senescence can be triggered by a DNA damage response due to the shortening of telomeres. Cells can also be induced to senesce by DNA damage in response to elevated...

structure. In addition to these stacked structures, telomeres also form large loop structures called telomere loops, or T-loops. Here, the single-stranded DNA...

His research has focused on the biology of blood-forming stem cells, telomeres and genome analysis. He is also known for developing techniques including...

Telomere resolvase, also known as protelomerase, is an enzyme found in bacteria which contain linear plasmids. In order to prevent exonuclease degradation...

playing structural and replicatory roles, such as scaffolding regions, telomeres, centromeres, and origins of replication, plus large numbers of transposable...

below: Primary hallmarks (causes of damage) Genome instability Telomere shortening (or telomere attrition) Epigenetic alterations Loss of proteostasis Antagonistic...

repeat–containing RNA (TERRA) is a long non-coding RNA transcribed from telomeres - repetitive nucleotide regions found on the ends of chromosomes that...

Ala-Glu-Asp-Gly and the molecular formula C14H22N4O9. Epitalon appears to induce telomere elongation via increased telomerase activity in human somatic cells in...

which both copies of each chromosome are identical led to the first telomere-to-telomere, truly complete sequence of a human chromosome, the X chromosome...

Nr2e3 gene. It has been suggested that L1s may directly contribute to telomere reprogramming at the 2-cell stage of embryo development. In 2021, a study...

presence of vestigial telomeres. These are normally found only at the ends of a chromosome, but in chromosome 2 there are additional telomere sequences in the...

but these components do not always occur. DKC is characterized by short telomeres. Some of the manifestations resemble premature ageing (similar to progeria)...

and telomere length regulation in immune cells and its malignant counterparts. He has worked on potential roles of telomerase activity and telomere length...

G-overhang at human telomere ends, which could inhibit the proper formation of the so-called T-loop, destabilizing the telomere as a whole. Telomere lengthening...