• Thumbnail for The Hallmarks of Cancer
    The idea was coined by Douglas Hanahan and Robert Weinberg in their paper "The Hallmarks of Cancer" published January 2000 in Cell. These hallmarks constitute...
    22 KB (2,497 words) - 18:49, 25 February 2024
  • Thumbnail for Metastasis
    Metastasis (redirect from Metastatic cancer)
    secondary) tumor. Metastasis is one of the hallmarks of cancer, distinguishing it from benign tumors. Most cancers can metastasize, although in varying...
    42 KB (4,999 words) - 10:20, 16 February 2024
  • Thumbnail for Douglas Hanahan
    Douglas Hanahan (category Members of the National Academy of Medicine)
    entitled "Hallmarks of cancer: the next generation". In 2022, Professor Hanahan published another updated review article, entitled "Hallmarks of Cancer: New...
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  • Thumbnail for Cancer
    the six hallmarks of cancer. These characteristics are required to produce a malignant tumor. They include: Cell growth and division absent the proper...
    186 KB (20,182 words) - 12:31, 28 April 2024
  • of the hallmarks of cancer (see below), will have a competitive advantage over cells that have not acquired the hallmark. Thus, at the level of the cell...
    87 KB (9,909 words) - 14:08, 16 February 2024
  • implications in the development and persistence of cancers as well as debilitating developmental diseases. One of the hallmarks of cancer formation and...
    12 KB (1,534 words) - 01:12, 29 January 2023
  • proposed further hallmarks or underlying mechanisms that drive multiple of these hallmarks. Each hallmark was chosen to try to fulfill the following criteria:...
    40 KB (4,313 words) - 04:16, 4 May 2024
  • Robert Weinberg (biologist) (category Members of the United States National Academy of Sciences)
    hard to identify the principles that cancers had in common. He and Douglas Hanahan wrote the seminal paper "The Hallmarks of Cancer", published in January...
    17 KB (1,319 words) - 00:45, 27 December 2023
  • alterations in the structure or number of chromosomes in cells. These changes can lead to uncontrolled cell growth, a hallmark of cancer. The theory originated...
    8 KB (844 words) - 18:05, 2 May 2024
  • Thumbnail for Chemotherapy
    PMID 19104514. S2CID 17934366. Hanahan D, Weinberg RA (January 2000). "The hallmarks of cancer". Cell. 100 (1): 57–70. doi:10.1016/S0092-8674(00)81683-9. PMID 10647931...
    154 KB (17,494 words) - 04:15, 13 March 2024
  • Avi Wigderson introduce the zig-zag product. January – Douglas Hanahan and Robert Weinberg publish "The Hallmarks of Cancer". January 31 – English doctor...
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  • Thumbnail for Lung cancer
    Table 73.1: Hallmarks of Cancer. Schabath & Cote 2019, "Introduction". Bade & Dela Cruz 2020, "Tobacco Smoke Carcinogens". "Tobacco and Cancer". Centers...
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  • influential research reports include: The Hallmarks of Cancer, published in 2000, and Hallmarks of Cancer: The Next Generation, published in 2011, by...
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  • tumorigenesis, is the formation of a cancer, whereby normal cells are transformed into cancer cells. The process is characterized by changes at the cellular,...
    115 KB (13,948 words) - 12:58, 26 April 2024
  • (1974–1999) The Hallmarks of Cancer "About Cell". Reed Elsevier. Archived from the original on 2010-03-23. Elsevier: Cell: Home Archived 2012-09-25 at the Wayback...
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  • PMID 6049107. S2CID 4150783. Hanahan, D.; Weinberg, R. (7 January 2000). "The Hallmarks of Cancer" (PDF). Cell. 100 (1): 57–70. doi:10.1016/s0092-8674(00)81683-9...
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  • hallmarks of cancer; however, hair follicle cells also grow and divide quickly. Consequently, the chemotherapy drugs usually inhibit hair growth. The...
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  • Thumbnail for Naked mole-rat
    does. The combination of p16 and p27 in naked mole-rat cells is a double barrier to uncontrolled cell proliferation, one of the hallmarks of cancer. In...
    47 KB (5,402 words) - 16:05, 16 April 2024
  • Thumbnail for Glycolysis
    Glycolysis (section Cancer)
    Schwartz L, Supuran CT, Alfarouk KO (2017). "The Warburg Effect and the Hallmarks of Cancer". Anti-Cancer Agents in Medicinal Chemistry. 17 (2): 164–170...
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  • Cancer is caused by genetic changes leading to uncontrolled cell growth and tumor formation. The basic cause of sporadic (non-familial) cancers is DNA...
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  • Thumbnail for Human papillomavirus infection
    Human papillomavirus infection (category Infectious causes of cancer)
    S2CID 71143679. Hanahan, Douglas; Weinberg, Robert A. (7 January 2000). "The Hallmarks of Cancer". Cell. 100 (1): 57–70. doi:10.1016/S0092-8674(00)81683-9. ISSN 0092-8674...
    145 KB (15,995 words) - 04:34, 14 March 2024
  • Thumbnail for DNA replication
    leading to cancer formation. Increased telomerase activity is one of the hallmarks of cancer. Termination requires that the progress of the DNA replication...
    60 KB (7,306 words) - 20:48, 25 March 2024
  • use of acetic acid bacteria to produce vinegar. One of the hallmarks of cancer is altered metabolism or deregulating cellular energetics. Cancers cells...
    28 KB (3,367 words) - 21:05, 30 November 2023
  • Kuruppu S, Prasongsook N (2016). "Effects of Animal Venoms and Toxins on Hallmarks of Cancer". Journal of Cancer. 7 (11): 1571–1578. doi:10.7150/jca.15309...
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  • Thumbnail for Tumor metabolome
    one of The Hallmarks of Cancer. High amount of aerobic glycolysis (also known as the Warburg effect) distinguishes cancer cells from normal cells. The conversion...
    22 KB (2,576 words) - 03:03, 28 November 2023
  • Paraskeva C, Kaidi A (March 2009). "The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment". Carcinogenesis...
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  • Thumbnail for Pleomorphism (cytology)
    cellular and nuclear pleomorphism is one of the earliest hallmarks of cancer progression and a feature characteristic of malignant neoplasms and dysplasia....
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  • (2000). "The hallmarks of cancer". Cell. 100 (1): 57–70. doi:10.1016/S0092-8674(00)81683-9. PMID 10647931. Fidler, I. J. (1973). "Selection of successive...
    53 KB (5,955 words) - 16:03, 30 March 2024
  • Thumbnail for Follicular dendritic cell sarcoma
    Follicular dendritic cell sarcoma (category Rare cancers)
    mitotic spindle, during cell division. This contributes to many of the hallmarks of cancer, including proliferative signaling, growth activation, and replicative...
    23 KB (2,551 words) - 08:00, 25 March 2024
  • Thumbnail for Cyclin-dependent kinase 6
    control is the first step to developing different hallmarks of cancer; alterations of CDK6 can directly or indirectly affect the following hallmarks; disregulated...
    35 KB (4,042 words) - 05:00, 1 April 2024