• Thumbnail for Toll-like receptor
    Toll-like receptors (TLRs) are a class of proteins that play a key role in the innate immune system. They are single-spanning receptors usually expressed...
    60 KB (6,685 words) - 09:55, 26 April 2024
  • Thumbnail for Toll-like receptor 9
    Toll-like receptor 9 is a protein that in humans is encoded by the TLR9 gene. TLR9 has also been designated as CD289 (cluster of differentiation 289)....
    20 KB (2,551 words) - 21:43, 4 April 2024
  • Thumbnail for Toll-like receptor 4
    Toll-like receptor 4 (TLR4), also designated as CD284 (cluster of differentiation 284), is a key activator of the innate immune response and plays a central...
    75 KB (9,082 words) - 21:42, 4 April 2024
  • Thumbnail for Toll-like receptor 2
    Toll-like receptor 2 also known as TLR2 is a protein that in humans is encoded by the TLR2 gene. TLR2 has also been designated as CD282 (cluster of differentiation...
    22 KB (2,409 words) - 21:42, 4 April 2024
  • Thumbnail for Toll-like receptor 3
    Toll-like receptor 3 (TLR3) also known as CD283 (cluster of differentiation 283) is a protein that in humans is encoded by the TLR3 gene. TLR3 is a member...
    9 KB (1,057 words) - 21:43, 4 April 2024
  • Thumbnail for Toll-like receptor 7
    Toll-like receptor 7, also known as TLR7, is a protein that in humans is encoded by the TLR7 gene. Orthologs are found in mammals and birds. It is a member...
    11 KB (1,264 words) - 21:43, 4 April 2024
  • Thumbnail for Toll-like receptor 8
    Toll-like receptor 8 is a protein that in humans is encoded by the TLR8 gene. TLR8 has also been designated as CD288 (cluster of differentiation 288)....
    9 KB (1,091 words) - 21:43, 4 April 2024
  • Thumbnail for Toll-like receptor 5
    Toll-like receptor 5, also known as TLR5, is a protein which in humans is encoded by the TLR5 gene. It is a member of the toll-like receptor (TLR) family...
    19 KB (2,255 words) - 05:11, 7 May 2024
  • Thumbnail for Toll-like receptor 6
    Toll-like receptor 6 is a protein that in humans is encoded by the TLR6 gene. TLR6 is a transmembrane protein, member of toll-like receptor family, which...
    8 KB (1,073 words) - 21:43, 4 April 2024
  • Thumbnail for Toll-like receptor 1
    Toll-like receptor 1 (TLR1) is a member of Toll-like receptors (TLRs), which is a family of pattern recognition receptors (PRRs) that form the cornerstone...
    12 KB (1,377 words) - 21:42, 4 April 2024
  • Thumbnail for Toll-like receptor 10
    Toll-like receptor 10 is a protein that in humans is encoded by the TLR10 gene. TLR10 has also been designated as CD290 (cluster of differentiation 290)...
    6 KB (833 words) - 19:32, 7 September 2023
  • include toll like receptors (TLRs) and C-type lectin receptors (CLRs). Cytoplasmic PRRs include NOD-like receptors (NLRs) and RIG-I-like receptors (RLRs)...
    43 KB (5,164 words) - 12:43, 14 April 2024
  • Thumbnail for MYD88
    activation through Toll-like receptors (TLRs), which belong to large group of pattern recognition receptors (PRR). In general, these receptors sense common...
    20 KB (2,250 words) - 09:33, 6 April 2024
  • Thumbnail for Toll-like receptor 11
    pseudogene. TLR11 belongs to the toll-like receptor (TLR) family and the interleukin-1 receptor/toll-like receptor superfamily. In mice, TLR11 has been...
    11 KB (1,460 words) - 08:55, 8 November 2023
  • by pathogens is, in part, due to the presence of immune receptors called toll-like receptors (TLRs) that are expressed on the membranes of leukocytes...
    37 KB (4,220 words) - 10:13, 27 March 2024
  • forwarder Toll Ipec, Australian transportation company Toll Resources & Government Logistics Toll (gene), encode members of the Toll-like receptor class of...
    2 KB (331 words) - 19:54, 19 May 2023
  • present in the host. They are recognized by toll-like receptors (TLRs) and other pattern recognition receptors (PRRs) in both plants and animals. This allows...
    13 KB (1,476 words) - 12:50, 13 January 2024
  • Thumbnail for NOD-like receptor
    recognition receptors (PRRs), and play key roles in the regulation of innate immune response. NLRs can cooperate with toll-like receptors (TLRs) and regulate...
    14 KB (1,532 words) - 23:00, 21 November 2023
  • bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2". Journal of Immunology. 163 (1): 1–5. doi:10.4049/jimmunol.163...
    36 KB (4,020 words) - 03:30, 12 May 2024
  • Thumbnail for Signal transduction
    et al. (August 2003). "Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway". Science. 301 (5633): 640–3. Bibcode:2003Sci.....
    63 KB (7,624 words) - 03:29, 26 January 2024
  • Thumbnail for CD14
    the first described pattern recognition receptor. CD14 acts as a co-receptor (along with the Toll-like receptor TLR 4 and MD-2) for the detection of bacterial...
    7 KB (845 words) - 09:05, 27 March 2024
  • wide interleukin-1 receptor (IL-1R) family are characterized by extracellular immunoglobulin-like domains and intracellular Toll/Interleukin-1R (TIR)...
    13 KB (1,572 words) - 21:44, 19 February 2023
  • components of the Interleukin-1 receptor signaling pathway and some Toll-like receptor signaling pathways. Toll-like receptors (TLRs) detect microorganisms...
    30 KB (3,637 words) - 16:01, 30 March 2024
  • Thumbnail for CD36
    CD36 (category Receptors)
    been shown to promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer. Recently, CD36 was linked to store-operated calcium...
    45 KB (5,216 words) - 03:41, 14 May 2024
  • Thumbnail for TIRAP
    molecule associated with toll-like receptors. The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify...
    1 KB (179 words) - 19:07, 9 June 2023
  • Thumbnail for Fc receptor
    "FcγRIIIa-Syk Co-signal Modulates CD4+ T-cell Response and Up-regulates Toll-like Receptor (TLR) Expression". J. Biol. Chem. 291 (3): 1368–86. doi:10.1074/jbc...
    42 KB (4,735 words) - 03:31, 26 March 2024
  • Thumbnail for IRAK4
    (interleukin-1 receptor-associated kinase 4), in the IRAK family, is a protein kinase involved in signaling innate immune responses from Toll-like receptors. It...
    20 KB (2,530 words) - 07:42, 21 December 2023
  • Thumbnail for Toll-interleukin receptor
    protein-protein interactions between the toll-like receptors (TLRs) and signal-transduction components. TIR-like motifs are also found in plant proteins...
    8 KB (839 words) - 21:44, 4 April 2024
  • Thumbnail for Lymphocyte antigen 96
    binding lipopolysaccharide with Toll-Like Receptor (TLR4). The MD-2 protein appears to associate with toll-like receptor 4 on the cell surface and confers...
    12 KB (1,492 words) - 13:13, 4 April 2024
  • Thumbnail for HMGB1
    form it can bind the inflammatory receptor RAGE (Receptor for Advanced Glycation End-products) and Toll-like receptors (TLRs). Release from cells seems...
    26 KB (3,154 words) - 13:09, 6 March 2024